ftsX:Gene Product(s)

From EcoliWiki
Jump to: navigation, search

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

FtsX

Synonyms

predicted transporter subunit: membrane component of ABC superfamily[1], B3462[2][1], FtsS[2][1], FtsX[2][1] , ECK3446, ftsS, JW3427, b3462

Product description

cell division protein FtsX[2][3];

Component of FtsE/FtsX ABC transporter[2][3]

Integral membrane protein invoved in cell division; binds FtsE to the inner membrane[4]

EC number (for enzymes)


edit table

<protect></protect>

Notes

Function

[back to top]


<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005515

protein binding

PMID:10048040[5]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc (v14.0)

complete

GO:0005886

plasma membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0997

C

Seeded from EcoCyc (v14.0)

complete

GO:0005886

plasma membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-1003

C

Seeded from EcoCyc (v14.0)

complete

GO:0007049

cell cycle

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004513

P

Seeded from EcoCyc (v14.0)

complete

GO:0007049

cell cycle

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0131

P

Seeded from EcoCyc (v14.0)

complete

GO:0016020

membrane

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003838

C

Seeded from EcoCyc (v14.0)

complete

GO:0005515

protein binding

PMID:10048040[5]

IDA: Inferred from Direct Assay

F

EcoliWiki:ftsE

complete

GO:0016020

membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

PMID:10048040[5]

IDA: Inferred from Direct Assay

C

complete

GO:0016021

integral to membrane

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004513

C

Seeded from EcoCyc (v14.0)

complete

GO:0051301

cell division

PMID:14729705[6]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0016021

integral to membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

Seeded from EcoCyc (v14.0)

complete

GO:0000910

cytokinesis

PMID:14729705[6]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0016021

integral to membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-9909

C

Seeded from EcoCyc (v14.0)

complete

GO:0032155

cell division site part

PMID:14729705[6]

IDA: Inferred from Direct Assay

C

complete

edit table

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of FtsE/FtsX ABC transporter

could be indirect

Protein

rplK

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rpsT

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rpsN

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rpsJ

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

acpP

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

cspC

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

atpF

PMID:19402753[7]

LCMS(ID Probability):99.4

Protein

rplL

PMID:19402753[7]

LCMS(ID Probability):99.6

edit table

</protect>

Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

plasma membrane

C-terminus localized in the cytoplasm with 4 predicted transmembrane domains

Daley et al. (2005) [8]

plasma membrane

From EcoCyc[3]


edit table

<protect></protect>

Notes

Structure and Physical Properties

[back to top]


<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MNKRDAINHI RQFGGRLDRF RKSVGGSGDG GRNAPKRAKS SPKPVNRKTN VFNEQVRYAF
HGALQDLKSK PFATFLTVMV IAISLTLPSV CYMVYKNVNQ AATQYYPSPQ ITVYLQKTLD
DDAAAGVVAQ LQAEQGVEKV NYLSREDALG EFRNWSGFGG ALDMLEENPL PAVAVVIPKL
DFQGTESLNT LRDRITQING IDEVRMDDSW FARLAALTGL VGRVSAMIGV LMVAAVFLVI
GNSVRLSIFA RRDSINVQKL IGATDGFILR PFLYGGALLG FSGALLSLIL SEILVLRLSS
AVAEVAQVFG TKFDINGLSF DECLLLLLVC SMIGWVAAWL ATVQHLRHFT PE
Length

352

Mol. Wt

38.544 kDa

pI

9.3 (calculated)

Extinction coefficient

33,920 - 34,295 (calc based on 8 Y, 4 W, and 3 C residues)

edit table


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

173..346

PF02687 Predicted permease

PMID:19920124[9]

edit table

<motif_map/>

tmhmm.php?gene=ftsX&show=pic&.jpg
Click the image to view raw output from TMHMM.

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=ftsX taxon=562,83333 </beststructure>

Models

View models at:

edit table
</protect>

Structure figures

<protect>

</protect>

Notes

Gene Product Resources

[back to top]


See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
edit table

<protect></protect>

Notes

Accessions in Other Databases

[back to top]


See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16131334

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:947969

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0011311

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P0AC30

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG10345

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10345

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:947969

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000339

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0341

Escherichia coli str. K-12 substr. MG1655

edit table

<protect></protect>

Notes

Links

[back to top]




References

[back to top]


See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 5.2 de Leeuw, E et al. (1999) Molecular characterization of Escherichia coli FtsE and FtsX. Mol. Microbiol. 31 983-93 PubMed
  6. ↑ 6.0 6.1 6.2 Schmidt, KL et al. (2004) A predicted ABC transporter, FtsEX, is needed for cell division in Escherichia coli. J. Bacteriol. 186 785-93 PubMed
  7. ↑ 7.0 7.1 7.2 7.3 7.4 7.5 7.6 7.7 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  8. ↑ Daley, DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308 1321-3 PubMed
  9. ↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

[back to top]


Retrieved from "https://ecoliwiki.org/colipedia/index.php?title=ftsX:Gene_Product(s)&oldid=1495246"