fimD:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

FimD

Synonyms

outer membrane usher protein, type 1 fimbrial synthesis[1], B4317[2][1], FimD_1[2][1], FimD[2][1], FimD_2[2][1] , ECK4308, JW5780, b4317

Product description

outer membrane protein; export and assembly of type 1 fimbriae[2][3]

Outer membrane fimbrial subunit export usher protein; involved in export and assembly of type 1 fimbrial subunits; FimCD chaperone-usher transport[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005215

transporter activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000015

F

Seeded from EcoCyc (v14.0)

complete

GO:0005886

plasma membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-1003

C

Seeded from EcoCyc (v14.0)

complete

GO:0006810

transport

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000015

P

Seeded from EcoCyc (v14.0)

complete

GO:0006810

transport

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0813

P

Seeded from EcoCyc (v14.0)

complete

GO:0009279

cell outer membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0998

C

Seeded from EcoCyc (v14.0)

complete

GO:0016020

membrane

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000015

C

Seeded from EcoCyc (v14.0)

complete

GO:0016020

membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-9909

C

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

groL

PMID:16606699[5]

Experiment(s):EBI-1139991

Protein

ygeY

PMID:16606699[5]

Experiment(s):EBI-1139991

Protein

mtlD

PMID:16606699[5]

Experiment(s):EBI-1139991

Protein

pepB

PMID:16606699[5]

Experiment(s):EBI-1139991

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

Outer Membrane

PMID:12842468

EchoLocation:fimD

outer membrane

From EcoCyc[3]


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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MSYLNLRLYQ RNTQCLHIRK HRLAGFFVRL VVACAFAAQA PLSSADLYFN PRFLADDPQA
VADLSRFENG QELPPGTYRV DIYLNNGYMA TRDVTFNTGD SEQGIVPCLT RAQLASMGLN
TASVAGMNLL ADDACVPLTT MVQDATAHLD VGQQRLNLTI PQAFMSNRAR GYIPPELWDP
GINAGLLNYN FSGNSVQNRI GGNSHYAYLN LQSGLNIGAW RLRDNTTWSY NSSDRSSGSK
NKWQHINTWL ERDIIPLRSR LTLGDGYTQG DIFDGINFRG AQLASDDNML PDSQRGFAPV
IHGIARGTAQ VTIKQNGYDI YNSTVPPGPF TINDIYAAGN SGDLQVTIKE ADGSTQIFTV
PYSSVPLLQR EGHTRYSITA GEYRSGNAQQ EKTRFFQSTL LHGLPAGWTI YGGTQLADRY
RAFNFGIGKN MGALGALSVD MTQANSTLPD DSQHDGQSVR FLYNKSLNES GTNIQLVGYR
YSTSGYFNFA DTTYSRMNGY NIETQDGVIQ VKPKFTDYYN LAYNKRGKLQ LTVTQQLGRT
STLYLSGSHQ TYWGTSNVDE QFQAGLNTAF EDINWTLSYS LTKNAWQKGR DQMLALNVNI
PFSHWLRSDS KSQWRHASAS YSMSHDLNGR MTNLAGVYGT LLEDNNLSYS VQTGYAGGGD
GNSGSTGYAT LNYRGGYGNA NIGYSHSDDI KQLYYGVSGG VLAHANGVTL GQPLNDTVVL
VKAPGAKDAK VENQTGVRTD WRGYAVLPYA TEYRENRVAL DTNTLADNVD LDNAVANVVP
TRGAIVRAEF KARVGIKLLM TLTHNNKPLP FGAMVTSESS QSSGIVADNG QVYLSGMPLA
GKVQVKWGEE ENAHCVANYQ LPPESQQQLL TQLSAECR
Length

878

Mol. Wt

96.483 kDa

pI

7.1 (calculated)

Extinction coefficient

141,530 - 142,280 (calc based on 47 Y, 13 W, and 6 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

motif

1-45

UniProt Manual:Signal Peptides

UniProt:P30130

Domain

47..862

PF00577 Fimbrial Usher protein

PMID:19920124[6]

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Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=fimD taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16132138

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:948844

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0014151

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P30130

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG10311

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10311

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:948844

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000305

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0307

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. 5.0 5.1 5.2 5.3 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  6. Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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