fecR:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

FecR

Synonyms

KpLE2 phage-like element; transmembrane signal transducer for ferric citrate transport[1], B4292[2][1], FecR[2][1] , ECK4282, JW4252, b4292

Product description

regulator for fec operon, periplasmic[2][3];

Component of FecAR Signal Transduction System[2][3]

Transmembrane signal transducer for ferric citrate transport; recognizes FecA:ferric citrate complex in periplasm and activates FecI sigma factor in cytoplasm[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005506

iron ion binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0408

F

Seeded from EcoCyc (v14.0)

complete

GO:0006810

transport

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0813

P

Seeded from EcoCyc (v14.0)

complete

GO:0006811

ion transport

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0406

P

Seeded from EcoCyc (v14.0)

complete

GO:0006826

iron ion transport

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0410

P

Seeded from EcoCyc (v14.0)

complete

GO:0042597

periplasmic space

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0574

C

Seeded from EcoCyc (v14.0)

complete

GO:0042597

periplasmic space

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0200

C

Seeded from EcoCyc (v14.0)

complete

GO:0050896

response to stimulus

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0716

P

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of FecAR Signal Transduction System

could be indirect

Protein

groL

PMID:16606699[5]

Experiment(s):EBI-1147814

Protein

insC1

PMID:16606699[5]

Experiment(s):EBI-1147814

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MNPLLTDSRR QALRSASHWY AVLSGERVSP QQEARWQQWY EQDQDNQWAW QQVENLRNQL
GGVPGDVASR ALHDTRLTRR HVMKGLLLLL GAGGGWQLWQ SETGEGLRAD YRTAKGTVSR
QQLEDGSLLT LNTQSAADVR FDAHQRTVRL WYGEIAITTA KDALQRPFRV LTRQGQLTAL
GTEFTVRQQD NFTQLDVQQH AVEVLLASAP AQKRIVNAGE SLQFSASEFG AVKPLDDEST
SWTKDILSFS DKPLGEVIAT LTRYRNGVLR CDPAVAGLRL SGTFPLKNTD AILNVIAQTL
PVKIQSITRY WINISPL
Length

317

Mol. Wt

35.531 kDa

pI

9.3 (calculated)

Extinction coefficient

63,940 - 64,065 (calc based on 6 Y, 10 W, and 1 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

109..203

PF04773 FecR protein

PMID:19920124[6]

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Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=fecR taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16132113

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:949104

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0014070

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P23485

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG10292

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10292

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:949104

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000286

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0288

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. 5.0 5.1 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  6. Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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