fdhE:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

FdhE

Synonyms

formate dehydrogenase formation protein[1], B3891[2][1], FdhE[2][1] , ECK3884, JW3862, b3891

Product description

protein that affects formate dehydrogenase-N activity[2][3]

Redox enzyme maturation protein (REMP) for FdnG/FdoG; required for formate dehydrogenase activity; probable cytoplasmic protein[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005515

protein binding

PMID:18716757[5]

IPI: Inferred from Physical Interaction

UniProtKB:P24183

F

Seeded from EcoCyc (v14.0)

complete

GO:0005515

protein binding

PMID:18716757[5]

IPI: Inferred from Physical Interaction

UniProtKB:P32176

F

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00611

C

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006452

C

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0963

C

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0086

C

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

dnaE

PMID:16606699[6]

Experiment(s):EBI-1146889

Protein

rpsI

PMID:16606699[6]

Experiment(s):EBI-1146889

Protein

fdoG

PMID:16606699[6]

Experiment(s):EBI-1146889

Protein

gltJ

PMID:16606699[6]

Experiment(s):EBI-1146889

Protein

cmoA

PMID:16606699[6]

Experiment(s):EBI-1146889

Protein

htrB

PMID:16606699[6]

Experiment(s):EBI-1146889

Protein

gmhB

PMID:16606699[6]

Experiment(s):EBI-1146889

Protein

rplN

PMID:16606699[6]

Experiment(s):EBI-1146889

Protein

rpsG

PMID:16606699[6]

Experiment(s):EBI-1146889

Protein

gyrA

PMID:16606699[6]

Experiment(s):EBI-1146889

Protein

can

PMID:16606699[6]

Experiment(s):EBI-1146889

Protein

nadE

PMID:16606699[6]

Experiment(s):EBI-1146889

Protein

rplQ

PMID:16606699[6]

Experiment(s):EBI-1146889

Protein

slyD

PMID:16606699[6]

Experiment(s):EBI-1146889

Protein

rplE

PMID:16606699[6]

Experiment(s):EBI-1146889

Protein

kdsD

PMID:16606699[6]

Experiment(s):EBI-1146889

Protein

rplV

PMID:16606699[6]

Experiment(s):EBI-1146889

Protein

rplF

PMID:16606699[6]

Experiment(s):EBI-1146889

Protein

groS

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):2.155644

Protein

rplD

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

iscR

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

aroG

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

fdnG

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):39.196044

Protein

fdoG

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):18.717783

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MSIRIIPQDE LGSSEKRTAD MIPPLLFPRL KNLYNRRAER LRELAENNPL GDYLRFAALI
AHAQEVVLYD HPLEMDLTAR IKEASAQGKP PLDIHVLPRD KHWQKLLMAL IAELKPEMSG
PALAVIENLE KASTQELEDM ASALFASDFS SVSSDKAPFI WAALSLYWAQ MANLIPGKAR
AEYGEQRQYC PVCGSMPVSS MVQIGTTQGL RYLHCNLCET EWHVVRVKCS NCEQSGKLHY
WSLDDEQAAI KAESCDDCDT YLKILYQEKD PKIEAVADDL ASLVLDARME QEGYARSSIN
PFLFPGEGE
Length

309

Mol. Wt

34.747 kDa

pI

4.9 (calculated)

Extinction coefficient

43,890 - 44,890 (calc based on 11 Y, 5 W, and 8 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

9..304

PF04216 Protein involved in formate dehydrogenase formation

PMID:19920124[8]

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=fdhE taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16131731

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:948384

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0012703

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P13024

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG10284

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10284

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:948384

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000278

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0280

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. 5.0 5.1 Lüke, I et al. (2008) Biosynthesis of the respiratory formate dehydrogenases from Escherichia coli: characterization of the FdhE protein. Arch. Microbiol. 190 685-96 PubMed
  6. 6.00 6.01 6.02 6.03 6.04 6.05 6.06 6.07 6.08 6.09 6.10 6.11 6.12 6.13 6.14 6.15 6.16 6.17 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  7. 7.0 7.1 7.2 7.3 7.4 7.5 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  8. Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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