fadE:Gene Product(s)

From EcoliWiki
Jump to: navigation, search

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

FadE

Synonyms

acyl coenzyme A dehydrogenase[1], B0221[2][1], FadE[2][1], YafH[2][1], FadF[2][1] , ECK0222, fadF, JW5020, yafH, b0221

Product description

Medium-long-chain fatty acyl-CoA dehydrogenase[3]

EC number (for enzymes)

<protect></protect>

Notes

Function

[back to top]


<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0016021

integral to membrane

C

Seeded from Riley et al 2006 [1].

Missing: evidence, reference

GO:0003995

acyl-CoA dehydrogenase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006091

F

Seeded from EcoCyc (v14.0)

complete

GO:0003995

acyl-CoA dehydrogenase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006092

F

Seeded from EcoCyc (v14.0)

complete

GO:0003995

acyl-CoA dehydrogenase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR015396

F

Seeded from EcoCyc (v14.0)

complete

GO:0006629

lipid metabolic process

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0443

P

Seeded from EcoCyc (v14.0)

complete

GO:0006631

fatty acid metabolic process

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0276

P

Seeded from EcoCyc (v14.0)

complete

GO:0016491

oxidoreductase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR013764

F

Seeded from EcoCyc (v14.0)

complete

GO:0016491

oxidoreductase activity

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0560

F

Seeded from EcoCyc (v14.0)

complete

GO:0016627

oxidoreductase activity, acting on the CH-CH group of donors

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006090

F

Seeded from EcoCyc (v14.0)

complete

GO:0016627

oxidoreductase activity, acting on the CH-CH group of donors

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR009075

F

Seeded from EcoCyc (v14.0)

complete

GO:0016627

oxidoreductase activity, acting on the CH-CH group of donors

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR009100

F

Seeded from EcoCyc (v14.0)

complete

GO:0016627

oxidoreductase activity, acting on the CH-CH group of donors

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR013786

F

Seeded from EcoCyc (v14.0)

complete

GO:0033539

fatty acid beta-oxidation using acyl-CoA dehydrogenase

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR015396

P

Seeded from EcoCyc (v14.0)

complete

GO:0050660

FAD binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR013786

F

Seeded from EcoCyc (v14.0)

complete

GO:0055114

oxidation reduction

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006090

P

Seeded from EcoCyc (v14.0)

complete

GO:0055114

oxidation reduction

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006091

P

Seeded from EcoCyc (v14.0)

complete

GO:0055114

oxidation reduction

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006092

P

Seeded from EcoCyc (v14.0)

complete

GO:0055114

oxidation reduction

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR009075

P

Seeded from EcoCyc (v14.0)

complete

GO:0055114

oxidation reduction

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR009100

P

Seeded from EcoCyc (v14.0)

complete

GO:0055114

oxidation reduction

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR013764

P

Seeded from EcoCyc (v14.0)

complete

GO:0055114

oxidation reduction

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR013786

P

Seeded from EcoCyc (v14.0)

complete

GO:0055114

oxidation reduction

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR015396

P

Seeded from EcoCyc (v14.0)

complete

GO:0055114

oxidation reduction

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0560

P

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

</protect>

Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

<protect></protect>

Notes

Structure and Physical Properties

[back to top]


<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MVRPPTSKGL FVMMILSILA TVVLLGALFY HRVSLFISSL ILLAWTAALG VAGLWSAWVL
VPLAIILVPF NFAPMRKSMI SAPVFRGFRK VMPPMSRTEK EAIDAGTTWW EGDLFQGKPD
WKKLHNYPQP RLTAEEQAFL DGPVEEACRM ANDFQITHEL ADLPPELWAY LKEHRFFAMI
IKKEYGGLEF SAYAQSRVLQ KLSGVSGILA ITVGVPNSLG PGELLQHYGT DEQKDHYLPR
LARGQEIPCF ALTSPEAGSD AGAIPDTGIV CMGEWQGQQV LGMRLTWNKR YITLAPIATV
LGLAFKLSDP EKLLGGAEDL GITCALIPTT TPGVEIGRRH FPLNVPFQNG PTRGKDVFVP
IDYIIGGPKM AGQGWRMLVE CLSVGRGITL PSNSTGGVKS VALATGAYAH IRRQFKISIG
KMEGIEEPLA RIAGNAYVMD AAASLITYGI MLGEKPAVLS AIVKYHCTHR GQQSIIDAMD
ITGGKGIMLG QSNFLARAYQ GAPIAITVEG ANILTRSMMI FGQGAIRCHP YVLEEMEAAK
NNDVNAFDKL LFKHIGHVGS NKVRSFWLGL TRGLTSSTPT GDATKRYYQH LNRLSANLAL
LSDVSMAVLG GSLKRRERIS ARLGDILSQL YLASAVLKRY DDEGRNEADL PLVHWGVQDA
LYQAEQAMDD LLQNFPNRVV AGLLNVVIFP TGRHYLAPSD KLDHKVAKIL QVPNATRSRI
GRGQYLTPSE HNPVGLLEEA LVDVIAADPI HQRICKELGK NLPFTRLDEL AHNALVKGLI
DKDEAAILVK AEESRLRSIN VDDFDPEELA TKPVKLPEKV RKVEAA
Length

826

Mol. Wt

90.54 kDa

pI

8.5 (calculated)

Extinction coefficient

98,780 - 99,780 (calc based on 22 Y, 12 W, and 8 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

360..508

PF00441 Acyl-CoA dehydrogenase, C-terminal domain

PMID:19920124[4]

Domain

237..297

PF02770 Acyl-CoA dehydrogenase, middle domain

PMID:19920124[4]

Domain

121..233

PF02771 Acyl-CoA dehydrogenase, N-terminal domain

PMID:19920124[4]

Domain

514..792

PF09317 Domain of unknown function (DUF1974)

PMID:19920124[4]

<motif_map/>

tmhmm.php?gene=fadE&show=pic&.jpg
Click the image to view raw output from TMHMM.

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=fadE taxon=562,83333 </beststructure>

Models

View models at:

</protect>

Structure figures

<protect>

</protect>

Notes

Gene Product Resources

[back to top]


See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

<protect></protect>

Notes

Accessions in Other Databases

[back to top]


See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:90111100

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:949007

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0000743

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:Q47146

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:G6105

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG13145

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:949007

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120002725

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB2939

Escherichia coli str. K-12 substr. MG1655

<protect></protect>

Notes

Links

[back to top]




References

[back to top]


See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  4. 4.0 4.1 4.2 4.3 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

[back to top]