dtpB:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

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Standard name

DtpB

Synonyms

predicted transporter[1], B3496[2][1], YhiP[2][1] , ECK3481, JW3463, yhiP, b3496

Product description

YhiP peptide POT transporter[2][3]

EC number (for enzymes)
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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki. See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005886

plasma membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0997

C

Seeded from EcoCyc (v14.0)

complete

GO:0005886

plasma membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-1003

C

Seeded from EcoCyc (v14.0)

complete

GO:0006857

oligopeptide transport

PMID:18485005[4]

IDA: Inferred from Direct Assay

P

Seeded from EcoCyc (v14.0)

complete

GO:0015293

symporter activity

PMID:18485005[4]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-9909

C

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

PMID:18485005[4]

IDA: Inferred from Direct Assay

C

Seeded from EcoCyc (v14.0)

complete

GO:0042936

dipeptide transporter activity

PMID:18485005[4]

IMP: Inferred from Mutant Phenotype

F

Seeded from EcoCyc (v14.0)

complete

GO:0042937

tripeptide transporter activity

PMID:18485005[4]

IMP: Inferred from Mutant Phenotype

F

Seeded from EcoCyc (v14.0)

complete

GO:0042938

dipeptide transport

PMID:18485005[4]

IMP: Inferred from Mutant Phenotype

P

Seeded from EcoCyc (v14.0)

complete

GO:0042939

tripeptide transport

PMID:18485005[4]

IMP: Inferred from Mutant Phenotype

P

Seeded from EcoCyc (v14.0)

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence
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Notes

Localization

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Compartment Description Evidence Reference/Source Notes

plasma membrane

C-terminus localized in the cytoplasm with 14 predicted transmembrane domains

Daley et al. (2005) [5]

plasma membrane

From EcoCyc[3]


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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MNTTTPMGML QQPRPFFMIF FVELWERFGY YGVQGVLAVF FVKQLGFSQE QAFVTFGAFA
ALVYGLISIG GYVGDHLLGT KRTIVLGALV LAIGYFMTGM SLLKPDLIFI ALGTIAVGNG
LFKANPASLL SKCYPPKDPR LDGAFTLFYM SINIGSLIAL SLAPVIADRF GYSVTYNLCG
AGLIIALLVY IACRGMVKDI GSEPDFRPMS FSKLLYVLLG SVVMIFVCAW LMHNVEVANL
VLIVLSIVVT IIFFRQAFKL DKTGRNKMFV AFVLMLEAVV FYILYAQMPT SLNFFAINNV
HHEILGFSIN PVSFQALNPF WVVLASPILA GIYTHLGNKG KDLSMPMKFT LGMFMCSLGF
LTAAAAGMWF ADAQGLTSPW FIVLVYLFQS LGELFISALG LAMIAALVPQ HLMGFILGMW
FLTQAAAFLL GGYVATFTAV PDNITDPLET LPVYTNVFGK IGLVTLGVAV VMLLMVPWLK
RMIATPESH
Length

489

Mol. Wt

53.577 kDa

pI

8.6 (calculated)

Extinction coefficient

63,830 - 64,455 (calc based on 17 Y, 7 W, and 5 C residues)

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Domains/Motifs/Modification Sites

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Type Residues Description Notes References

Domain

81..428

PF00854 POT family

PMID:19920124[6]

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<motif_map/>

tmhmm.php?gene=yhiP&show=pic&.jpg
Click the image to view raw output from TMHMM.

Structure
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Structures

<beststructure> gene=dtpB taxon=562,83333 </beststructure>

Models

View models at:

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</protect>

Structure figures

<protect>

</protect>

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16131368

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:948006

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0011417

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P36837

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG12232

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG12232

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:948006

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120002116

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB2144

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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  1. ↑ 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 Harder, D et al. (2008) DtpB (YhiP) and DtpA (TppB, YdgR) are prototypical proton-dependent peptide transporters of Escherichia coli. FEBS J. 275 3290-8 PubMed
  5. ↑ Daley, DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308 1321-3 PubMed
  6. ↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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