dmsA:Gene Product(s)

From EcoliWiki
Jump to: navigation, search

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

DmsA

Synonyms

dimethyl sulfoxide reductase, anaerobic, subunit A[1], B0894[2][1], DmsA[2][1] , ECK0885, JW5118, b0894

Product description

dimethyl sulfoxide reductase, chain A[2][3];

Component of dimethyl sulfoxide reductase[2][3]

DMSO reductase subunit A, anaerobic, periplasmic[4]

EC number (for enzymes)
edit table

<protect></protect>

Notes

Function

[back to top]


<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0030288

outer membrane-bounded periplasmic space

C

Seeded from Riley et al 2006 [1].

Missing: evidence, reference

GO:0005506

iron ion binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0408

F

Seeded from EcoCyc (v14.0)

complete

GO:0005506

iron ion binding

PMID:1653010[5]

IMP: Inferred from Mutant Phenotype

F

Seeded from EcoCyc (v14.0)

complete

GO:0005886

plasma membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-1003

C

Seeded from EcoCyc (v14.0)

complete

GO:0006810

transport

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:3062312

P

Seeded from EcoCyc (v14.0)

complete

GO:0009055

electron carrier activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006655

F

Seeded from EcoCyc (v14.0)

complete

GO:0009055

electron carrier activity

PMID:8125918[6]

IMP: Inferred from Mutant Phenotype

F

Seeded from EcoCyc (v14.0)

complete

GO:0009061

anaerobic respiration

PMID:2544558[7]

IEP: Inferred from Expression Pattern

P

Seeded from EcoCyc (v14.0)

complete

GO:0009389

dimethyl sulfoxide reductase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011888

F

Seeded from EcoCyc (v14.0)

complete

GO:0009390

dimethyl sulfoxide reductase complex

PMID:3280546[8]

IDA: Inferred from Direct Assay

C

Seeded from EcoCyc (v14.0)

complete

GO:0016020

membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

Seeded from EcoCyc (v14.0)

complete

GO:0016491

oxidoreductase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006655

F

Seeded from EcoCyc (v14.0)

complete

GO:0016491

oxidoreductase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006656

F

Seeded from EcoCyc (v14.0)

complete

GO:0016491

oxidoreductase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006657

F

Seeded from EcoCyc (v14.0)

complete

GO:0016491

oxidoreductase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006963

F

Seeded from EcoCyc (v14.0)

complete

GO:0016491

oxidoreductase activity

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0560

F

Seeded from EcoCyc (v14.0)

complete

GO:0030151

molybdenum ion binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006657

F

Seeded from EcoCyc (v14.0)

complete

GO:0030151

molybdenum ion binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011888

F

Seeded from EcoCyc (v14.0)

complete

GO:0030151

molybdenum ion binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0500

F

Seeded from EcoCyc (v14.0)

complete

GO:0030151

molybdenum ion binding

PMID:1653010[5]

IMP: Inferred from Mutant Phenotype

F

Seeded from EcoCyc (v14.0)

complete

GO:0051539

4 iron, 4 sulfur cluster binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011888

F

Seeded from EcoCyc (v14.0)

complete

GO:0051539

4 iron, 4 sulfur cluster binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0004

F

Seeded from EcoCyc (v14.0)

complete

GO:0051539

4 iron, 4 sulfur cluster binding

PMID:1653010[5]

IMP: Inferred from Mutant Phenotype

F

Seeded from EcoCyc (v14.0)

complete

GO:0055114

oxidation reduction

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011888

P

Seeded from EcoCyc (v14.0)

complete

GO:0055114

oxidation reduction

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0560

P

Seeded from EcoCyc (v14.0)

complete

edit table

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of dimethyl sulfoxide reductase

could be indirect


edit table

</protect>

Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

cytoplasm

Periplasm

PMID:3062312[9]

EchoLocation:dmsA


edit table

<protect></protect>

Notes

Structure and Physical Properties

[back to top]


<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MASSALTLPF SRIAHAVDSA IPTKSDEKVI WSACTVNCGS RCPLRMHVVD GEIKYVETDN
TGDDNYDGLH QVRACLRGRS MRRRVYNPDR LKYPMKRVGA RGEGKFERIS WEEAYDIIAT
NMQRLIKEYG NESIYLNYGT GTLGGTMTRS WPPGNTLVAR LMNCCGGYLN HYGDYSSAQI
AEGLNYTYGG WADGNSPSDI ENSKLVVLFG NNPGETRMSG GGVTYYLEQA RQKSNARMII
IDPRYTDTGA GREDEWIPIR PGTDAALVNG LAYVMITENL VDQAFLDKYC VGYDEKTLPA
SAPKNGHYKA YILGEGPDGV AKTPEWASQI TGVPADKIIK LAREIGSTKP AFISQGWGPQ
RHANGEIATR AISMLAILTG NVGINGGNSG AREGSYSLPF VRMPTLENPI QTSISMFMWT
DAIERGPEMT ALRDGVRGKD KLDVPIKMIW NYAGNCLINQ HSEINRTHEI LQDDKKCELI
VVIDCHMTSS AKYADILLPD CTASEQMDFA LDASCGNMSY VIFNDQVIKP RFECKTIYEM
TSELAKRLGV EQQFTEGRTQ EEWMRHLYAQ SREAIPELPT FEEFRKQGIF KKRDPQGHHV
AYKAFREDPQ ANPLTTPSGK IEIYSQALAD IAATWELPEG DVIDPLPIYT PGFESYQDPL
NKQYPLQLTG FHYKSRVHST YGNVDVLKAA CRQEMWINPL DAQKRGIHNG DKVRIFNDRG
EVHIEAKVTP RMMPGVVALG EGAWYDPDAK RVDKGGCINV LTTQRPSPLA KGNPSHTNLV
QVEKV
Length

785

Mol. Wt

87.45 kDa

pI

6.6 (calculated)

Extinction coefficient

123,650 - 125,525 (calc based on 35 Y, 13 W, and 15 C residues)

edit table


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

motif

1-45

UniProt Manual:Signal Peptides

UniProt:P18775

Domain

56..116

PF04879 Molybdopterin oxidoreductase Fe4S4 domain

PMID:19920124[10]

Domain

119..576

PF00384 Molybdopterin oxidoreductase

PMID:19920124[10]

Domain

695..808

PF01568 Molydopterin dinucleotide binding domain

PMID:19920124[10]

edit table

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=dmsA taxon=562,83333 </beststructure>

Models

View models at:

edit table
</protect>

Structure figures

<protect>

</protect>

Notes

Gene Product Resources

[back to top]


See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
edit table

<protect></protect>

Notes

Accessions in Other Databases

[back to top]


See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:90111183

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:945508

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0003044

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P18775

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG10232

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10232

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:945508

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000226

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0228

Escherichia coli str. K-12 substr. MG1655

edit table

<protect></protect>

Notes

Links

[back to top]




References

[back to top]


See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 5.2 Rothery, RA & Weiner, JH (1991) Alteration of the iron-sulfur cluster composition of Escherichia coli dimethyl sulfoxide reductase by site-directed mutagenesis. Biochemistry 30 8296-305 PubMed
  6. ↑ Trieber, CA et al. (1994) Multiple pathways of electron transfer in dimethyl sulfoxide reductase of Escherichia coli. J. Biol. Chem. 269 7103-9 PubMed
  7. ↑ Cotter, PA & Gunsalus, RP (1989) Oxygen, nitrate, and molybdenum regulation of dmsABC gene expression in Escherichia coli. J. Bacteriol. 171 3817-23 PubMed
  8. ↑ Weiner, JH et al. (1988) Purification and properties of Escherichia coli dimethyl sulfoxide reductase, an iron-sulfur molybdoenzyme with broad substrate specificity. J. Bacteriol. 170 1505-10 PubMed
  9. ↑ Bilous, PT et al. (1988) Nucleotide sequence of the dmsABC operon encoding the anaerobic dimethylsulphoxide reductase of Escherichia coli. Mol. Microbiol. 2 785-95 PubMed
  10. ↑ 10.0 10.1 10.2 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

[back to top]


Retrieved from "https://ecoliwiki.org/colipedia/index.php?title=dmsA:Gene_Product(s)&oldid=1492876"