dmlR:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

DmlR

Synonyms

predicted DNA-binding transcriptional regulator[1], B1799[2][1], YeaT[2][1] DmlR[3], DmlR, ECK1797, JW1788, yeaT, b1799

Product description

predicted DNA-binding transcriptional regulator[2][4]

Positive transcriptional regulator for yeaU[5]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003677

DNA binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0238

F

Seeded from EcoCyc (v14.0)

complete

GO:0003700

transcription factor activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000847

F

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

rtcB

PMID:16606699[6]

Experiment(s):EBI-1140853

Protein

rplF

PMID:16606699[6]

Experiment(s):EBI-1140853

Protein

groL

PMID:16606699[6]

Experiment(s):EBI-1140853

Protein

ftsZ

PMID:16606699[6]

Experiment(s):EBI-1140853

Protein

ydeH

PMID:16606699[6]

Experiment(s):EBI-1140853

Protein

recA

PMID:16606699[6]

Experiment(s):EBI-1140853

Protein

mqo

PMID:16606699[6]

Experiment(s):EBI-1140853

Protein

rplE

PMID:16606699[6]

Experiment(s):EBI-1140853

Protein

glpK

PMID:16606699[6]

Experiment(s):EBI-1140853

Protein

tusE

PMID:16606699[6]

Experiment(s):EBI-1140853

Protein

rpsB

PMID:16606699[6]

Experiment(s):EBI-1140853

Protein

rsuA

PMID:16606699[6]

Experiment(s):EBI-1140853

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MKHKTRIMNN LPLLNDLRVF MLVARRAGFA AVAEELGVSP AFVSKRIALL EQTLNVVLLH
RTTRRVTITE EGERIYEWAQ RILQDVGQMM DELSDVRQVP QGMLRIISSF GFGRQVVAPA
LLALAKAYPQ LELRFDVEDR LVDLVNEGVD LDIRIGDDIA PNLIARKLAT NYRILCASPE
FIAQHGAPKH LTDLSALPCL VIKERDHPFG VWQLRNKEGP HAIKVTGPLS SNHGEIVHQW
CLDGQGIALR SWWDVSENIA SGHLVQVLPE YYQPANVWAV YVSRLATSAK VRITVEFLRQ
YFAEHYPNFS LEHA
Length

314

Mol. Wt

35.525 kDa

pI

7.4 (calculated)

Extinction coefficient

44,920 - 45,295 (calc based on 8 Y, 6 W, and 3 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

90..296

PF03466 LysR substrate binding domain

PMID:19920124[7]

Domain

7..66

PF00126 Bacterial regulatory helix-turn-helix protein, lysR family

PMID:19920124[7]

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=yeaT taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:90111335

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:946316

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0005987

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P76250

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:G6985

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG13506

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:946316

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120003572

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB3279

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. Lukas, H et al. (2010) Regulation of aerobic and anaerobic D-malate metabolism of Escherichia coli by the LysR-type regulator DmlR (YeaT). J. Bacteriol. 192 2503-11 PubMed
  4. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  5. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  6. 6.00 6.01 6.02 6.03 6.04 6.05 6.06 6.07 6.08 6.09 6.10 6.11 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  7. 7.0 7.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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