cspD:Gene Product(s)
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| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
| Standard name |
CspD |
|---|---|
| Synonyms |
cold shock protein homolog[1], B0880[2][1], YbjA[2][1], CspD[2][1] , cspH, ECK0871, JW0864, ybjA, b0880 |
| Product description |
DNA replication inhibitor[2][3]; Component of cold shock protein homolog[3] Inhibitor of DNA replication; cold shock protein homolog, not cold shock inducible; stationary phase and starvation inducible; lethal when overproduced[4] |
| EC number (for enzymes) |
|
| edit table |
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Notes
Function
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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003676 |
nucleic acid binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003676 |
nucleic acid binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003676 |
nucleic acid binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003677 |
DNA binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003677 |
DNA binding |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003723 |
RNA binding |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005737 |
cytoplasm |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005737 |
cytoplasm |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005737 |
cytoplasm |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0086 |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006355 |
regulation of transcription, DNA-dependent |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006355 |
regulation of transcription, DNA-dependent |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006950 |
response to stress |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0008156 |
negative regulation of DNA replication |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003697 |
single-stranded DNA binding |
IDA: Inferred from Direct Assay |
F |
Figure 4 |
complete | |||
| GO:0042594 |
response to starvation |
IDA: Inferred from Direct Assay |
P |
Figure 4 |
complete | |||
| edit table |
Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
| Partner Type | Partner | Notes | References | Evidence |
|---|---|---|---|---|
|
Protein |
Subunits of cold shock protein homolog |
could be indirect |
||
|
Protein |
aceE |
Experiment(s):EBI-879539 | ||
|
Protein |
cspC |
Experiment(s):EBI-879539, EBI-883767, EBI-883980 | ||
|
Protein |
cspE |
Experiment(s):EBI-879539 | ||
|
Protein |
deaD |
Experiment(s):EBI-879539 | ||
|
Protein |
pnp |
Experiment(s):EBI-879539 | ||
|
Protein |
rho |
Experiment(s):EBI-879539 | ||
|
Protein |
rplA |
Experiment(s):EBI-879539 | ||
|
Protein |
rplB |
Experiment(s):EBI-879539 | ||
|
Protein |
rplC |
Experiment(s):EBI-879539, EBI-883767 | ||
|
Protein |
rpsA |
Experiment(s):EBI-879539 | ||
|
Protein |
rpsB |
Experiment(s):EBI-879539, EBI-883767 | ||
|
Protein |
rpsC |
Experiment(s):EBI-879539 | ||
|
Protein |
rpsE |
Experiment(s):EBI-879539, EBI-883767 | ||
|
Protein |
rpsG |
Experiment(s):EBI-879539, EBI-883767 | ||
|
Protein |
rpsM |
Experiment(s):EBI-879539 | ||
|
Protein |
tehB |
Experiment(s):EBI-879539 | ||
|
Protein |
rnr |
Experiment(s):EBI-879539 | ||
|
Protein |
ycbY |
Experiment(s):EBI-879539 | ||
|
Protein |
rluC |
Experiment(s):EBI-879539 | ||
|
Protein |
rluB |
Experiment(s):EBI-879539 | ||
|
Protein |
accA |
Experiment(s):EBI-879539 | ||
|
Protein |
rpsD |
Experiment(s):EBI-879539, EBI-883767 | ||
|
Protein |
acrD |
Experiment(s):EBI-883767 | ||
|
Protein |
aspA |
Experiment(s):EBI-883767 | ||
|
Protein |
ddpB |
Experiment(s):EBI-883767 | ||
|
Protein |
ddlA |
Experiment(s):EBI-883767 | ||
|
Protein |
dppD |
Experiment(s):EBI-883767 | ||
|
Protein |
skp |
Experiment(s):EBI-883767 | ||
|
Protein |
hupA |
Experiment(s):EBI-883767 | ||
|
Protein |
rplM |
Experiment(s):EBI-883767 | ||
|
Protein |
rplS |
Experiment(s):EBI-883767 | ||
|
Protein |
rplX |
Experiment(s):EBI-883767 | ||
|
Protein |
rpsJ |
Experiment(s):EBI-883767 | ||
|
Protein |
rpsN |
Experiment(s):EBI-883767 | ||
|
Protein |
rpsT |
Experiment(s):EBI-883767 | ||
|
Protein |
rpsU |
Experiment(s):EBI-883767 | ||
|
Protein |
ydiA |
Experiment(s):EBI-883767 | ||
|
Protein |
yfiF |
Experiment(s):EBI-883767 | ||
|
Protein |
rho |
MALDI(Z-score):37.446310 | ||
|
Protein |
ddlA |
LCMS(ID Probability):99.0 | ||
|
Protein |
rpsJ |
LCMS(ID Probability):99.6 MALDI(Z-score):5.368742 | ||
|
Protein |
skp |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpsN |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpsT |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpsA |
MALDI(Z-score):24.834488 | ||
|
Protein |
rplS |
LCMS(ID Probability):99.0 MALDI(Z-score):4.578737 | ||
|
Protein |
rpsU |
LCMS(ID Probability):99.6 | ||
|
Protein |
rplM |
LCMS(ID Probability):99.6 MALDI(Z-score):5.962325 | ||
|
Protein |
rpsC |
MALDI(Z-score):25.075789 | ||
|
Protein |
aspA |
LCMS(ID Probability):99.0 | ||
|
Protein |
rpsM |
MALDI(Z-score):26.386877 | ||
|
Protein |
rplX |
LCMS(ID Probability):99.6 | ||
|
Protein |
rplB |
MALDI(Z-score):29.727578 | ||
|
Protein |
rpsD |
LCMS(ID Probability):99.0 MALDI(Z-score):35.563879 | ||
|
Protein |
ppsR |
LCMS(ID Probability):99.0 | ||
|
Protein |
rplA |
LCMS(ID Probability):95.4 MALDI(Z-score):31.394353 | ||
|
Protein |
rlmL |
MALDI(Z-score):20.841640 | ||
|
Protein |
acrD |
LCMS(ID Probability):99.0 | ||
|
Protein |
cspE |
LCMS(ID Probability):97.9 MALDI(Z-score):17.053160 | ||
|
Protein |
yfiF |
LCMS(ID Probability):99.0 MALDI(Z-score):19.466810 | ||
|
Protein |
rnr |
MALDI(Z-score):23.323615 | ||
|
Protein |
rluC |
MALDI(Z-score):26.672161 | ||
|
Protein |
deaD |
MALDI(Z-score):25.179680 | ||
|
Protein |
rluB |
MALDI(Z-score):35.756062 | ||
|
Protein |
cspC |
LCMS(ID Probability):99.6 MALDI(Z-score):17.053160 | ||
|
Protein |
dppD |
LCMS(ID Probability):99.0 | ||
|
Protein |
ddpB |
LCMS(ID Probability):99.0 | ||
| edit table |
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Notes
Localization
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
| Compartment | Description | Evidence | Reference/Source | Notes |
|---|---|---|---|---|
|
Nucleoid |
| |||
| edit table |
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Notes
Structure and Physical Properties
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Physical Properties
See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
| Name | |
|---|---|
| Sequence |
MEKGTVKWFN NAKGFGFICP EGGGEDIFAH YSTIQMDGYR TLKAGQSVQF DVHQGPKGNH ASVIVPVEVE AAVA |
| Length |
74 |
| Mol. Wt |
7.968 kDa |
| pI |
6.2 (calculated) |
| Extinction coefficient |
8,480 - 8,605 (calc based on 2 Y, 1 W, and 1 C residues) |
| edit table |
Domains/Motifs/Modification Sites
|
See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
|
<motif_map/> |
|
Structure
| </protect>
Structure figures<protect> | ||||||
Notes
Gene Product Resources
See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.
| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
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Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
| Database | Accession | Notes |
|---|---|---|
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
| edit table |
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Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ Yamanaka, K et al. (2001) CspD, a novel DNA replication inhibitor induced during the stationary phase in Escherichia coli. Mol. Microbiol. 39 1572-84 PubMed
- ↑ Yamanaka, K & Inouye, M (1997) Growth-phase-dependent expression of cspD, encoding a member of the CspA family in Escherichia coli. J. Bacteriol. 179 5126-30 PubMed
- ↑ 7.00 7.01 7.02 7.03 7.04 7.05 7.06 7.07 7.08 7.09 7.10 7.11 7.12 7.13 7.14 7.15 7.16 7.17 7.18 7.19 7.20 7.21 7.22 7.23 7.24 7.25 7.26 7.27 7.28 7.29 7.30 7.31 7.32 7.33 7.34 7.35 7.36 7.37 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
- ↑ 8.00 8.01 8.02 8.03 8.04 8.05 8.06 8.07 8.08 8.09 8.10 8.11 8.12 8.13 8.14 8.15 8.16 8.17 8.18 8.19 8.20 8.21 8.22 8.23 8.24 8.25 8.26 8.27 8.28 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
- ↑ Giangrossi, M et al. (2001) Different in vivo localization of the Escherichia coli proteins CspD and CspA. FEMS Microbiol. Lett. 202 171-6 PubMed
- ↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed
Categories
- GO:0003676 ! nucleic acid binding
- GO:0003677 ! DNA binding
- GO:0003723 ! RNA binding
- GO:0005737 ! cytoplasm
- GO:0006355 ! regulation of transcription, DNA-templated
- GO:0006950 ! response to stress
- GO:0008156 ! negative regulation of DNA replication
- GO:0003697 ! single-stranded DNA binding
- GO:0042594 ! response to starvation
- Proteins
- RefGenome Annotated Gene
