cpdA:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

CpdA

Synonyms

cyclic 3',5'-adenosine monophosphate phosphodiesterase[1], B3032[2][1], CpdA[2][1], Icc[2][1] , ECK3023, icc, JW3000, b3032

Product description

cAMP phosphodiesterase[2][3]

3',5' cAMP phosphodiesterase; mutants have elevated cAMP levels[4]

EC number (for enzymes)
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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0016787

hydrolase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004843

F

Seeded from EcoCyc (v14.0)

complete

GO:0008233

peptidase activity

F

Seeded from Riley et al 2006 [1].

Missing: evidence, reference

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

gadX

PMID:16606699[5]

Experiment(s):EBI-1144597

Protein

ribB

PMID:16606699[5]

Experiment(s):EBI-1144597

Protein

lldR

PMID:16606699[5]

Experiment(s):EBI-1144597

Protein

dam

PMID:16606699[5]

Experiment(s):EBI-1144597

Protein

groL

PMID:16606699[5]

Experiment(s):EBI-1144597

Protein

kdsA

PMID:16606699[5]

Experiment(s):EBI-1144597

Protein

yafY

PMID:16606699[5]

Experiment(s):EBI-1144597

Protein

yfeT

PMID:16606699[5]

Experiment(s):EBI-1144597
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes
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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MESLLTLPLA GEARVRILQI TDTHLFAQKH EALLGVNTWE SYQAVLEAIR PHQHEFDLIV
ATGDLAQDQS SAAYQHFAEG IASFRAPCVW LPGNHDFQPA MYSALQDAGI SPAKRVFIGE
QWQILLLDSQ VFGVPHGELS EFQLEWLERK LADAPERHTL LLLHHHPLPA GCSWLDQHSL
RNAGELDTVL AKFPHVKYLL CGHIHQELDL DWNGRRLLAT PSTCVQFKPH CSNFTLDTIA
PGWRTLELHA DGTLTTEVHR LADTRFQPDT ASEGY
Length

275

Mol. Wt

30.937 kDa

pI

5.9 (calculated)

Extinction coefficient

45,950 - 46,575 (calc based on 5 Y, 7 W, and 5 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

15..207

PF00149 Calcineurin-like phosphoesterase

PMID:19920124[6]

Domain

213..250

PF08413 Calcineurin-like phosphoesterase C-terminal

PMID:19920124[6]

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Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=cpdA taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16130928

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:947515

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0009957

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P0AEW4

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:G7579

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG12187

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:947515

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120004136

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB2104

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 5.2 5.3 5.4 5.5 5.6 5.7 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  6. ↑ 6.0 6.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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