cobT:Gene Product(s)

From EcoliWiki
Jump to: navigation, search

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

CobT

Synonyms

nicotinate-nucleotide dimethylbenzimidazole-P phophoribosyl transferase[1], B1991[2][1], CobT[2][1] , ECK1986, JW1969, b1991

Product description

CobT[2][3];

Component of dimethylbenzimidazole phosphoribosyltransferase[2]; nicotinate-nucleotide dimethylbenzimidazole phosphoribosyltransferase[3]

Partial cobalamin biosynthesis pathway present in E. coli[4]

EC number (for enzymes)
edit table

<protect></protect>

Notes

Function

[back to top]


<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005737

cytoplasm

C

Seeded from Riley et al 2006 [1].

Missing: evidence, reference

GO:0008939

nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00230

F

Seeded from EcoCyc (v14.0)

complete

GO:0008939

nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003200

F

Seeded from EcoCyc (v14.0)

complete

GO:0008939

nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017846

F

Seeded from EcoCyc (v14.0)

complete

GO:0008939

nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity

GOA:spec
GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:2.4.2.21

F

Seeded from EcoCyc (v14.0)

complete

GO:0009163

nucleoside biosynthetic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017846

P

Seeded from EcoCyc (v14.0)

complete

GO:0009236

cobalamin biosynthetic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003200

P

Seeded from EcoCyc (v14.0)

complete

GO:0009236

cobalamin biosynthetic process

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0169

P

Seeded from EcoCyc (v14.0)

complete

GO:0015420

cobalamin-transporting ATPase activity

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00230

F

Seeded from EcoCyc (v14.0)

complete

GO:0009236

cobalamin biosynthetic process

PMID:7592411[5]

IMP: Inferred from Mutant Phenotype

P

Table 2

complete

edit table

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of dimethylbenzimidazole phosphoribosyltransferase

could be indirect

Protein

glpD

PMID:16606699[6]

Experiment(s):EBI-1141584

Protein

gshB

PMID:16606699[6]

Experiment(s):EBI-1141584

Protein

zwf

PMID:16606699[6]

Experiment(s):EBI-1141584

Protein

groL

PMID:16606699[6]

Experiment(s):EBI-1141584

Protein

amn

PMID:16606699[6]

Experiment(s):EBI-1141584
edit table

</protect>

Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes
edit table

<protect></protect>

Notes

Structure and Physical Properties

[back to top]


<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MQILADLLNT IPAIDSTAMS RAQRHIDGLL KPVGSLGKLE VLAIQLAGMP GLNGIPHVGK
KAVLVMCADH GVWEEGVAIS PKEVTAIQAE NMTRGTTGVC VLAEQAGANV HVIDVGIDTA
EPIPGLINMR VARGSGNIAS APAMSRRQAE KLLLDVICYT QELAKNGVTL FGVGELGMAN
TTPAAAIVST ITGRDPEEVV GIGANLPTDK LANKIDVVRR AITLNQPNPQ DGVDVLAKVG
GFDLVGIAGV MLGAASCGLP VLLDGFLSYA AALAACQMSP AIKPYLIPSH LSAEKGARIA
LSHLGLEPYL NMEMRLGEGS GAALAMPIIE AACAIYNNMG ELAASNIVLP GNTTSDLNS
Length

359

Mol. Wt

36.987 kDa

pI

5.1 (calculated)

Extinction coefficient

12,950 - 13,700 (calc based on 5 Y, 1 W, and 6 C residues)

edit table


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

7..347

PF02277 Phosphoribosyltransferase

PMID:19920124[7]

edit table

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=cobT taxon=562,83333 </beststructure>

Models

View models at:

edit table
</protect>

Structure figures

<protect>

</protect>

Notes

Gene Product Resources

[back to top]


See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
edit table

<protect></protect>

Notes

Accessions in Other Databases

[back to top]


See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16129932

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:946517

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0006611

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P36562

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG12151

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG12151

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:946517

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120002050

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB2071

Escherichia coli str. K-12 substr. MG1655

edit table

<protect></protect>

Notes

Links

[back to top]




References

[back to top]


See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ Lawrence, JG & Roth, JR (1995) The cobalamin (coenzyme B12) biosynthetic genes of Escherichia coli. J. Bacteriol. 177 6371-80 PubMed
  6. ↑ 6.0 6.1 6.2 6.3 6.4 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  7. ↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

[back to top]


Retrieved from "https://ecoliwiki.org/colipedia/index.php?title=cobT:Gene_Product(s)&oldid=1493897"