caiC:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

CaiC

Synonyms

predicted crotonobetaine CoA ligase:carnitine CoA ligase[1], B0037[2][1], YaaM[2][1], CaiC[2][1] , ECK0038, JW0036, yaaM, b0037

Product description

CAIC[2][3]

Crotonobetain/carnitine-CoA ligase[4]

EC number (for enzymes)

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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005737

cytoplasm

C

Seeded from Riley et al 2006 [1].

Missing: evidence, reference

GO:0008152

metabolic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000873

P

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

dnaK

PMID:16606699[5]

Experiment(s):EBI-1135392

Protein

uvrD

PMID:16606699[5]

Experiment(s):EBI-1135392

Protein

araF

PMID:16606699[5]

Experiment(s):EBI-1135392

</protect>

Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

plasma membrane

From EcoCyc[3]


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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MDRGAMDIIG GQHLRQMWDD LADVYGHKTA LICESSGGVV NRYSYLELNQ EINRTANLFY
TLGIRKGDKV ALHLDNCPEF IFCWFGLAKI GAIMVPINAR LLCEESAWIL QNSQACLLVT
SAQFYPMYQQ IQQEDATQLR HICLTDVALP ADDGVSSFTQ LKNQQPATLC YAPPLSTDDT
AEILFTSGTT SRPKGVVITH YNLRFAGYYS AWQCALRDDD VYLTVMPAFH IDCQCTAAMA
AFSAGATFVL VEKYSARAFW GQVQKYRATV TECIPMMIRT LMVQPPSAND QQHRLREVMF
YLNLSEQEKD AFCERFGVRL LTSYGMTETI VGIIGDRPGD KRRWPSIGRV GFCYEAEIRD
DHNRPLPAGE IGEICIKGIP GKTIFKEYFL NPQATAKVLE ADGWLHTGDT GYRDEEDFFY
FVDRRCNMIK RGGENVSCVE LENIIAAHPK IQDIVVVGIK DSIRDEAIKA FVVLNEGETL
SEEEFFRFCE QNMAKFKVPS YLEIRKDLPR NCSGKIIRKN LK
Length

522

Mol. Wt

59.09 kDa

pI

5.8 (calculated)

Extinction coefficient

68,300 - 70,550 (calc based on 20 Y, 7 W, and 18 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

39..451

PF00501 AMP-binding enzyme

PMID:19920124[6]

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=caiC taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:221800780

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0000133

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P31552

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG11558

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG11558

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:944886

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120001511

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:944886

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB1519

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. 5.0 5.1 5.2 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  6. Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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