bioC:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

BioC

Synonyms

predicted methltransferase, enzyme of biotin synthesis[1], B0777[2][1], BioC[2][1] , ECK0766, JW0760, b0777

Product description

predicted methyltransferase, enzyme of biotin synthesis[2][3]

Biotin synthesis blocked prior to pimeloyl CoA formation; putative SAM-dependent methyltransferase[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0008168

methyltransferase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR013216

F

Seeded from EcoCyc (v14.0)

complete

GO:0008168

methyltransferase activity

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0489

F

Seeded from EcoCyc (v14.0)

complete

GO:0009102

biotin biosynthetic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011814

P

Seeded from EcoCyc (v14.0)

complete

GO:0009102

biotin biosynthetic process

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0093

P

Seeded from EcoCyc (v14.0)

complete

GO:0016740

transferase activity

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0808

F

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

groL

PMID:16606699[5]

Experiment(s):EBI-1137933

Protein

rsuA

PMID:16606699[5]

Experiment(s):EBI-1137933

Protein

prs

PMID:16606699[5]

Experiment(s):EBI-1137933

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MATVNKQAIA AAFGRAAAHY EQHADLQRQS ADALLAMLPQ RKYTHVLDAG CGPGWMSRHW
RERHAQVTAL DLSPPMLVQA RQKDAADHYL AGDIESLPLA TATFDLAWSN LAVQWCGNLS
TALRELYRVV RPKGVVAFTT LVQGSLPELH QAWQAVDERP HANRFLPPDE IEQSLNGVHY
QHHIQPITLW FDDALSAMRS LKGIGATHLH EGRDPRILTR SQLQRLQLAW PQQQGRYPLT
YHLFLGVIAR E
Length

251

Mol. Wt

28.275 kDa

pI

8.3 (calculated)

Extinction coefficient

48,930 - 49,180 (calc based on 7 Y, 7 W, and 2 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

47..138

PF08241 Methyltransferase domain

PMID:19920124[6]

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=bioC taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16128745

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:945388

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0002648

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P12999

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG10119

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10119

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:945388

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000115

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0117

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. 5.0 5.1 5.2 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  6. Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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