bamC:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

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Standard name

NlpB

Synonyms

lipoprotein[1], B2477[2][1], DapX[2][1], NlpB[2][1], lipoprotein-34[3][1]; BamC [4] , dapX, ECK2473, JW2462, nlpB, b2477

Product description

lipoprotein-34[2]; NlpB-lipoprotein component of outer membrane protein assembly complex[3];

Component of Outer Membrane Protein Assembly Complex[3]

EC number (for enzymes)

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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki. See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005886

plasma membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-1003

C

Seeded from EcoCyc (v14.0)

complete

GO:0005515

protein binding

PMID:15851030[5]

IPI: Inferred from Physical Interaction

EcoliWiki:yaeT EcoliWiki:yfgL EcoliWiki:yfiO


F

complete

GO:0009279

cell outer membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0998

C

Seeded from EcoCyc (v14.0)

complete

GO:0043165

Gram-negative-bacterium-type cell outer membrane assembly

PMID:15851030[5]

IGI: Inferred from Genetic Interaction

EcoliWiki:yaeT EcoliWiki:yfgL EcoliWiki:yfiO


P

complete

GO:0016020

membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

Seeded from EcoCyc (v14.0)

complete

GO:0031225

anchored to membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-9901

C

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of Outer Membrane Protein Assembly Complex

Protein

rfaS

PMID:16606699[6]

Experiment(s):EBI-1142993

Protein

phnN

PMID:16606699[6]

Experiment(s):EBI-1142993

Protein

serB

PMID:16606699[6]

Experiment(s):EBI-1142993

Protein

nadE

PMID:16606699[6]

Experiment(s):EBI-1142993

Protein

BamA (yaeT)

BamC (NlpB) is part of the BamCDE subcomplex. The BamCDE subcomplex interacts with BamA (YaeT) [7],[8].

Protein

BamD (yfiO)

BamD (YfiO) is part of the BamCDE subcomplex. BamD interacts with BamA (YaeT) directly. This interaction is stabilized by BamC (NlpB) and BamE (SmpA) [7],[8].

Protein

BamE (smpA)

BamE (SmpA) is part of the BamCDE subcomplex. [8].


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Notes

Localization

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Compartment Description Evidence Reference/Source Notes

outer membrane

Outer membrane

PMID:10806384

EchoLocation:nlpB


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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MMAYSVQKSR LAKVAGVSLV LLLAACSSDS RYKRQVSGDE AYLEAAPLAE LHAPAGMILP
VTSGDYAIPV TNGSGAVGKA LDIRPPAQPL ALVSGARTQF TGDTASLLVE NGRGNTLWPQ
VVSVLQAKNY TITQRDDAGQ TLTTDWVQWN RLDEDEQYRG RYQISVKPQG YQQAVTVKLL
NLEQAGKPVA DAASMQRYST EMMNVISAGL DKSATDAANA AQNRASTTMD VQSAADDTGL
PMLVVRGPFN VVWQRLPAAL EKVGMKVTDS TRSQGNMAVT YKPLSDSDWQ ELGASDPGLA
SGDYKLQVGD LDNRSSLQFI DPKGHTLTQS QNDALVAVFQ AAFSK
Length

345

Mol. Wt

36.973 kDa

pI

4.4 (calculated)

Extinction coefficient

43,890 - 44,015 (calc based on 11 Y, 5 W, and 1 C residues)

See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

motif

1-24

UniProt Manual:Signal Peptides

UniProt:P0A903

Domain

40..343

PF06804 NlpB/DapX lipoprotein

PMID:19920124[9]

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=bamC taxon=562,83333 </beststructure>

Models

View models at:

See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

</protect>

Structure figures

<protect>

</protect>

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:90111442

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:946954

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0008161

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P0A903

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG10658

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10658

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:946954

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000651

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0652

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. 5.0 5.1 Wu, T et al. (2005) Identification of a multicomponent complex required for outer membrane biogenesis in Escherichia coli. Cell 121 235-45 PubMed
  6. 6.0 6.1 6.2 6.3 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  7. 7.0 7.1 Malinverni, JC et al. (2006) YfiO stabilizes the YaeT complex and is essential for outer membrane protein assembly in Escherichia coli. Mol. Microbiol. 61 151-64 PubMed
  8. 8.0 8.1 8.2 Sklar, JG et al. (2007) Lipoprotein SmpA is a component of the YaeT complex that assembles outer membrane proteins in Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 104 6400-5 PubMed
  9. Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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