emrE:Quickview

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
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Standard Name

emrE

Gene Synonym(s)

ECK0534, b0543, JW0531, mvrC, eb, mvrB, G6299[1][2]

Product Desc.

EmrE SMR transporter[2][3]

Multidrug resistance pump, DLP12 prophage; methylviologen sensitivity[4]

Product Synonyms(s)

DLP12 prophage; multidrug resistance protein[1], B0543[2][1], MvrC[2][1], EmrE[2][1] , eb, ECK0534, JW0531, mvrC, b0543

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): renD[2]

Regulation/Activity
Quick Links

porteco.png EcoCyc.gif regulondb.jpg

dnadisplay.png proteindisplay.png   pubmed.jpg   textpresso.jpg  

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Notes

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EmrE defunct PDB structures 1S7B and 2F2M, and any conclusions derived from these structures, have been retracted due to a software data inversion error (Ma, 2007; Chang, 2007). Correct structures are now available. EmrE belongs to the SMR efflux pump family, DMT superfamily. EmrE accomplishes multidrug efflux by coupling conformational changes between two heterodimers with proton gradient. Dual-topology membrane protein.[4]



References

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  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.