ascG:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

AscG

Synonyms

DNA-binding transcriptional repressor[1], B2714[2][1], Sac[2][1], AscG[2][1] , ECK2709, JW5434, sac, b2714

Product description

AscG transcriptional repressor[2][3]

Repressor of cryptic asc operon[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003700

transcription factor activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000843

F

Seeded from EcoCyc (v14.0)

complete

GO:0003700

transcription factor activity

PMID:1630307[5]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc (v14.0)

complete

GO:0003700

transcription factor activity

PMID:1630307[5]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P03024

F

Seeded from EcoCyc (v14.0)

complete

GO:0005622

intracellular

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000843

C

Seeded from EcoCyc (v14.0)

complete

GO:0016566

specific transcriptional repressor activity

PMID:1630307[5]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc (v14.0)

complete

GO:0016566

specific transcriptional repressor activity

PMID:1630307[5]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P03024

F

Seeded from EcoCyc (v14.0)

complete

GO:0032582

negative regulation of gene-specific transcription

PMID:1630307[5]

IDA: Inferred from Direct Assay

P

Seeded from EcoCyc (v14.0)

complete

GO:0032582

negative regulation of gene-specific transcription

PMID:1630307[5]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P03024

P

Seeded from EcoCyc (v14.0)

complete

GO:0043565

sequence-specific DNA binding

PMID:1630307[5]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc (v14.0)

complete

GO:0043565

sequence-specific DNA binding

PMID:1630307[5]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P03024

F

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MMTTMLEVAK RAGVSKATVS RVLSGNGYVS QETKDRVFQA VEESGYRPNL LARNLSAKST
QTLGLVVTNT LYHGIYFSEL LFHAARMAEE KGRQLLLADG KHSAEEERQA IQYLLDLRCD
AIMIYPRFLS VDEIDDIIDA HSQPIMVLNR RLRKNSSHSV WCDHKQTSFN AVAELINAGH
QEIAFLTGSM DSPTSIERLA GYKDALAQHG IALNEKLIAN GKWTPASGAE GVEMLLERGA
KFSALVASND DMAIGAMKAL HERGVAVPEQ VSVIGFDDIA IAPYTVPALS SVKIPVTEMI
QEIIGRLIFM LDGGDFSPPK TFSGKLIRRD SLIAPSR
Length

337

Mol. Wt

36.945 kDa

pI

6.6 (calculated)

Extinction coefficient

22,920 - 23,170 (calc based on 8 Y, 2 W, and 2 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

4..49

PF00356 Bacterial regulatory proteins, lacI family

PMID:19920124[6]

Domain

60..311

PF00532 family

PMID:19920124[6]

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Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=ascG taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16130621

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:947305

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0008922

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P24242

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG10087

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10087

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:947305

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000083

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0085

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. 5.0 5.1 5.2 5.3 5.4 5.5 5.6 5.7 Hall, BG & Xu, L (1992) Nucleotide sequence, function, activation, and evolution of the cryptic asc operon of Escherichia coli K12. Mol. Biol. Evol. 9 688-706 PubMed
  6. 6.0 6.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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