appY:Gene Product(s)
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| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
| Standard name |
AppY |
|---|---|
| Synonyms |
DLP12 prophage; DNA-binding transcriptional activator[1], B0564[2][1], AppY[2][1], regulatory protein affecting appA and other genes[2][1] , ECK0556, JW0553, b0564 |
| Product description |
AppY transcriptional activator[2][3] Global transcription regulator, AraC family, DLP12 prophage[4] |
| EC number (for enzymes) |
|
| edit table |
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Notes
Function
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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003700 |
transcription factor activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003700 |
transcription factor activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003700 |
transcription factor activity |
IMP: Inferred from Mutant Phenotype |
F |
Seeded from EcoCyc (v14.0) |
complete | |||
| GO:0003700 |
transcription factor activity |
ISS: Inferred from Sequence or Structural Similarity |
Swiss-Prot:P27029 |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003700 |
transcription factor activity |
IDA: Inferred from Direct Assay |
F |
Seeded from EcoCyc (v14.0) |
complete | |||
| GO:0003700 |
transcription factor activity |
IDA: Inferred from Direct Assay |
F |
Seeded from EcoCyc (v14.0) |
complete | |||
| GO:0005622 |
intracellular |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005622 |
intracellular |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0016036 |
cellular response to phosphate starvation |
IDA: Inferred from Direct Assay |
P |
Seeded from EcoCyc (v14.0) |
complete | |||
| GO:0016036 |
cellular response to phosphate starvation |
IDA: Inferred from Direct Assay |
P |
Seeded from EcoCyc (v14.0) |
complete | |||
| GO:0016563 |
transcription activator activity |
IMP: Inferred from Mutant Phenotype |
F |
Seeded from EcoCyc (v14.0) |
complete | |||
| GO:0016563 |
transcription activator activity |
ISS: Inferred from Sequence or Structural Similarity |
Swiss-Prot:P27029 |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0016563 |
transcription activator activity |
IDA: Inferred from Direct Assay |
F |
Seeded from EcoCyc (v14.0) |
complete | |||
| GO:0016563 |
transcription activator activity |
IDA: Inferred from Direct Assay |
F |
Seeded from EcoCyc (v14.0) |
complete | |||
| GO:0043193 |
positive regulation of gene-specific transcription |
IMP: Inferred from Mutant Phenotype |
P |
Seeded from EcoCyc (v14.0) |
complete | |||
| GO:0043193 |
positive regulation of gene-specific transcription |
ISS: Inferred from Sequence or Structural Similarity |
Swiss-Prot:P27029 |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0043193 |
positive regulation of gene-specific transcription |
IDA: Inferred from Direct Assay |
P |
Seeded from EcoCyc (v14.0) |
complete | |||
| GO:0043193 |
positive regulation of gene-specific transcription |
IDA: Inferred from Direct Assay |
P |
Seeded from EcoCyc (v14.0) |
complete | |||
| GO:0043565 |
sequence-specific DNA binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0043565 |
sequence-specific DNA binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| edit table |
Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
| Partner Type | Partner | Notes | References | Evidence |
|---|---|---|---|---|
|
Protein |
glnD |
Experiment(s):EBI-1137163 | ||
|
Protein |
relE |
Experiment(s):EBI-1137163 | ||
|
Protein |
nadE |
Experiment(s):EBI-1137163 | ||
|
Protein |
fdhE |
Experiment(s):EBI-1137163 | ||
|
Protein |
rpsI |
Experiment(s):EBI-1137163 | ||
|
Protein |
iscS |
Experiment(s):EBI-1137163 | ||
|
Protein |
rplD |
Experiment(s):EBI-1137163 | ||
|
Protein |
ddpC |
Experiment(s):EBI-1137163 | ||
|
Protein |
hyaB |
Experiment(s):EBI-1137163 | ||
|
Protein |
yciH |
Experiment(s):EBI-1137163 | ||
|
Protein |
caiB |
Experiment(s):EBI-1137163 | ||
|
Protein |
ahpF |
Experiment(s):EBI-1137163 | ||
|
Protein |
rplB |
Experiment(s):EBI-1137163 | ||
|
Protein |
glpC |
Experiment(s):EBI-1137163 | ||
|
Protein |
rtcB |
Experiment(s):EBI-1137163 | ||
| edit table |
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Notes
Localization
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
| Compartment | Description | Evidence | Reference/Source | Notes |
|---|---|---|---|---|
| edit table |
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Notes
Structure and Physical Properties
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Physical Properties
See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
| Name | |
|---|---|
| Sequence |
MDYVCSVVFI CQSFDLIINR RVISFKKNSL FIVSDKIRRE LPVCPSKLRI VDIDKKTCLS FFIDVNNELP GKFTLDKNGY IAEEEPPLSL VFSLFEGIKI ADSHSLWLKE RLCISLLAMF KKRESVNSFI LTNINTFTCK ITGIISFNIE RQWHLKDIAE LIYTSESLIK KRLRDEGTSF TEILRDTRMR YAKKLITSNS YSINVVAQKC GYNSTSYFIC AFKDYYGVTP SHYFEKIIGV TDGINKTID |
| Length |
249 |
| Mol. Wt |
28.764 kDa |
| pI |
8.9 (calculated) |
| Extinction coefficient |
25,900 - 26,900 (calc based on 10 Y, 2 W, and 8 C residues) |
| edit table |
Domains/Motifs/Modification Sites
|
See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
|
<motif_map/> |
|
Structure
| </protect>
Structure figures<protect> | ||||||
Notes
Gene Product Resources
See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.
| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
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Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
| Database | Accession | Notes |
|---|---|---|
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
| edit table |
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Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ 5.0 5.1 5.2 Yang, H et al. (2004) Identification of mutator genes and mutational pathways in Escherichia coli using a multicopy cloning approach. Mol. Microbiol. 53 283-95 PubMed
- ↑ 6.0 6.1 6.2 Gallegos, MT et al. (1993) The XylS/AraC family of regulators. Nucleic Acids Res. 21 807-10 PubMed
- ↑ 7.0 7.1 7.2 7.3 Brøndsted, L & Atlung, T (1996) Effect of growth conditions on expression of the acid phosphatase (cyx-appA) operon and the appY gene, which encodes a transcriptional activator of Escherichia coli. J. Bacteriol. 178 1556-64 PubMed
- ↑ 8.0 8.1 8.2 Atlung, T et al. (1997) Effects of sigmaS and the transcriptional activator AppY on induction of the Escherichia coli hya and cbdAB-appA operons in response to carbon and phosphate starvation. J. Bacteriol. 179 2141-6 PubMed
- ↑ Moukadiri, I et al. (1997) Identification of a mannoprotein present in the inner layer of the cell wall of Saccharomyces cerevisiae. J. Bacteriol. 179 2154-62 PubMed
- ↑ 10.00 10.01 10.02 10.03 10.04 10.05 10.06 10.07 10.08 10.09 10.10 10.11 10.12 10.13 10.14 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
- ↑ 11.0 11.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed
Categories
- GO:0003700 ! DNA-binding transcription factor activity
- GO:0005622 ! intracellular
- GO:0016036 ! cellular response to phosphate starvation
- GO:0016563 ! obsolete transcription activator activity
- GO:0043193 ! positive regulation of gene-specific transcription
- GO:0043565 ! sequence-specific DNA binding
- Proteins
