adiA:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

AdiA

Synonyms

biodegradative arginine decarboxylase[1], B4117[2][1], AdiA[2][1], Adi[2][1] , adi, ECK4110, JW5731, b4117

Product description

Adi[2][3];

Component of arginine decarboxylase, degradative[2][3]

Arginine decarboxylase, acid-inducible; arginine-dependent acid resistance[4]

EC number (for enzymes)

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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0008792

arginine decarboxylase activity

PMID:4870599[5]

IDA: Inferred from Direct Assay

F

complete

GO:0005625

soluble fraction

PMID:4870599[5]

IDA: Inferred from Direct Assay

C

complete

GO:0006527

arginine catabolic process

PMID:4870599[5]

IDA: Inferred from Direct Assay

P

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of arginine decarboxylase, degradative

could be indirect

Protein

rplB

PMID:15690043[6]

Experiment(s):EBI-880730

Protein

rplO

PMID:15690043[6]

Experiment(s):EBI-880730

Protein

rrmJ

PMID:15690043[6]

Experiment(s):EBI-886815

Protein

sucA

PMID:15690043[6]

Experiment(s):EBI-886815

Protein

yahF

PMID:15690043[6]

Experiment(s):EBI-886815

Protein

ybgI

PMID:15690043[6]

Experiment(s):EBI-886815

Protein

ybgI

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

sucA

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rlmE

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rplB

PMID:19402753[7]

MALDI(Z-score):39.306923

Protein

yahF

PMID:19402753[7]

LCMS(ID Probability):99.6

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

cytoplasm

From EcoCyc[3]


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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MMKVLIVESE FLHQDTWVGN AVERLADALS QQNVTVIKST SFDDGFAILS SNEAIDCLMF
SYQMEHPDEH QNVRQLIGKL HERQQNVPVF LLGDREKALA AMDRDLLELV DEFAWILEDT
ADFIAGRAVA AMTRYRQQLL PPLFSALMKY SDIHEYSWAA PGHQGGVGFT KTPAGRFYHD
YYGENLFRTD MGIERTSLGS LLDHTGAFGE SEKYAARVFG ADRSWSVVVG TSGSNRTIMQ
ACMTDNDVVV VDRNCHKSIE QGLMLTGAKP VYMVPSRNRY GIIGPIYPQE MQPETLQKKI
SESPLTKDKA GQKPSYCVVT NCTYDGVCYN AKEAQDLLEK TSDRLHFDEA WYGYARFNPI
YADHYAMRGE PGDHNGPTVF ATHSTHKLLN ALSQASYIHV REGRGAINFS RFNQAYMMHA
TTSPLYAICA SNDVAVSMMD GNSGLSLTQE VIDEAVDFRQ AMARLYKEFT ADGSWFFKPW
NKEVVTDPQT GKTYDFADAP TKLLTTVQDC WVMHPGESWH GFKDIPDNWS MLDPIKVSIL
APGMGEDGEL EETGVPAALV TAWLGRHGIV PTRTTDFQIM FLFSMGVTRG KWGTLVNTLC
SFKRHYDANT PLAQVMPELV EQYPDTYANM GIHDLGDTMF AWLKENNPGA RLNEAYSGLP
VAEVTPREAY NAIVDNNVEL VSIENLPGRI AANSVIPYPP GIPMLLSGEN FGDKNSPQVS
YLRSLQSWDH HFPGFEHETE GTEIIDGIYH VMCVKA
Length

756

Mol. Wt

84.556 kDa

pI

5.1 (calculated)

Extinction coefficient

123,190 - 124,440 (calc based on 31 Y, 14 W, and 10 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

140..590

PF01276 Orn/Lys/Arg decarboxylase, major domain

PMID:19920124[8]

Domain

615..747

PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain

PMID:19920124[8]

Domain

16..134

PF03709 Orn/Lys/Arg decarboxylase, N-terminal domain

PMID:19920124[8]

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=adiA taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:221800782

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:948638

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0013483

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P28629

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG11501

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG11501

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:948638

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120001457

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB1464

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. 5.0 5.1 5.2 Blethen, SL et al. (1968) Argenine decarboxylase from Escherichia coli. I. Purification and specificity for substrates and coenzyme. J. Biol. Chem. 243 1671-7 PubMed
  6. 6.0 6.1 6.2 6.3 6.4 6.5 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
  7. 7.0 7.1 7.2 7.3 7.4 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  8. 8.0 8.1 8.2 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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