Phage lambda kil:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

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Standard name

kil

Synonyms

kil, lambdap85

Product description

host-killing protein

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0039633

killing by virus of host cells

PMID:1098278[1]

IGI: Inferred from Genetic Interaction

EcoliWiki:Phage_lambda_N EcoliWiki:Phage_lambda_O EcoliWiki:Phage_lambda_P


P

Phage must be N+O-P- to show kil phenotype.

complete

GO:0051782

negative regulation of cell division

PMID:12441108[2]

IGI: Inferred from Genetic Interaction

EcoliWiki:Phage_lambda_ea22


P

ea22- kil- mutants are unable to arrest host DNA replication at the non-permissive temperature. ea22- kil+ lysogens are able to both arrest DNA initiation & cell division in the host, indicating the role of kil in regulating host cell division.

complete

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Interactions <protect> See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence
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Notes

Localization

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Compartment Description Evidence Reference/Source Notes
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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence 
MDQTLMAIQT KFTIATFIGD EKMFREAVDA YKKWILILKL RSSKSIH
Length

47

Mol. Wt

5.518 kDa

pI

10.0 (calculated)

Extinction coefficient

6,990 (calc based on 1 Y, 1 W, and 0 C residues)

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Domains/Motifs/Modification Sites

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Type Residues Description Notes References
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<motif_map/>

Structure
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Structures

<beststructure> gene=Phage_lambda_kil taxon=10710 </beststructure>

Models

View models at:

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</protect>

Structure figures

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</protect>

Notes

Gene Product Resources

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Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes
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Notes

Links

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Name URL Comments
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References

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  1. ↑ Greer, H (1975) The kil gene of bacteriophage lambda. Virology 66 589-604 PubMed
  2. ↑ Sergueev, K et al. (2002) E.coli cell-cycle regulation by bacteriophage lambda. J. Mol. Biol. 324 297-307 PubMed

Categories

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