Phage T7 2:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

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Standard name

2

Synonyms
Product description

inhibits E. coli RNA polymerase

EC number (for enzymes)



Notes

Function

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Gene Ontology <protect> See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status


Interactions

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Partner Type Partner Notes References Evidence


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Notes

gp2 inhibits transcription by host RNA polymerase[1]. This inhibition is needed to prevent transcription of early promoters late in phage development [2]

Localization

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Compartment Description Evidence Reference/Source Notes



Notes

Structure and Physical Properties

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Physical Properties <protect> See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence
MSNVNTGSLS VDNKKFWATV ESSEHSFEVP IYAETLDEAL ELAEWQYVPA GFEVTRVRPC VAPK
Length

64

Mol. Wt

7.174 kDa

pI

4.5 (calculated)

Extinction coefficient

13,980 - 14,105 (calc based on 2 Y, 2 W, and 1 C residues)


Domains/Motifs/Modification Sites

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Type Residues Description Notes References

<motif_map/>

Structure

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Structures

<beststructure> gene=Phage_T7_2 taxon=10760 </beststructure>

Models

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</protect>

Structure figures

Notes

Gene Product Resources


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Resource type Source Notes/Reference


Notes

Accessions in Other Databases


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Database Accession Notes


Notes

Links





References


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  1. ↑ Nechaev, S & Severinov, K (1999) Inhibition of Escherichia coli RNA polymerase by bacteriophage T7 gene 2 protein. J. Mol. Biol. 289 815-26 PubMed
  2. ↑ Savalia, D et al. (2010) The role of the T7 Gp2 inhibitor of host RNA polymerase in phage development. J. Mol. Biol. 402 118-26 PubMed

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