Phage Qbeta A2:Gene Product(s)
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
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| Standard name |
A2 |
|---|---|
| Synonyms |
1, A2 maturation protein [1], A protein [2], maturation protein [2] |
| Product description |
minor coat protein & lysis protein |
| EC number (for enzymes) |
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Notes
Function
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Gene Ontology
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See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0019076 |
release of virus from host |
IDA: Inferred from Direct Assay |
P |
complete | ||||
| GO:0019077 |
lytic viral release |
IDA: Inferred from Direct Assay |
P |
complete | ||||
| GO:0004857 |
enzyme inhibitor activity |
IDA: Inferred from Direct Assay |
F |
A2 inhibits MurA (first dedicated step in cell wall/peptidoglycan biosynthesis). |
complete | |||
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Interactions
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| Partner Type | Partner | Notes | References | Evidence |
|---|---|---|---|---|
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Notes
Localization
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| Compartment | Description | Evidence | Reference/Source | Notes |
|---|---|---|---|---|
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Notes
Structure and Physical Properties
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Physical Properties
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See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
| Name | |
|---|---|
| Sequence |
MPRLPRALRF GPNMEVLSDF QELWYPESII DSDVKYPLYT FRGSIGGSFF DSYGTNNIVR EIRRTPHCAT VPIASSGLRP CTSVWYDPTS LLFRIPEMRA EWDNGMGDAG DIVYKDFLFS TPAPKEFDFS NSLAPRYSNA FSAFNAKYGV IIGEGHETLK YFALLLRRLH KAVRAVRHGD LRGLRKILDS YNKGRWKPAT AGNLWLEFRY GLTPLFHDIK SVMDDWNRIN DKIQKLRRFS VGHGEDFKLS IDGLYPGLTH FRLSGEITVQ RRHRWGITYA NREGYATFDN GSIRPVSDWK ELANAFINPG EVAWELTPYS FIVDWFINVG DIIEQQKQWY QNIDIVDGYQ RRDIRMRSVS LKGVRNGIPV RVTGSVELVD SFYNRSHTTR IPQATLAIDT SFSSIKHVMD SISLITQRIK R |
| Length |
421 |
| Mol. Wt |
48.487 kDa |
| pI |
9.8 (calculated) |
| Extinction coefficient |
87,320 - 87,570 (calc based on 18 Y, 11 W, and 2 C residues) |
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Domains/Motifs/Modification Sites
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Structure
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Structure figures<protect> | ||||||
Notes
Gene Product Resources
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| Resource type | Source | Notes/Reference |
|---|---|---|
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Notes
Accessions in Other Databases
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See Help:Gene_accessions for help with entering information into the Gene Accessions table.
| Database | Accession | Notes |
|---|---|---|
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Notes
Links
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| Name | URL | Comments |
|---|---|---|
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References
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- ↑ NCBI: Bacteriophage Qbeta A2 maturation protein, coat protein, A1 read-through protein, and Q beta replicase genes, complete cds: http://www.ncbi.nlm.nih.gov/nuccore/AY099114.1
- ↑ 2.0 2.1 NCBI: Enterobacteria phage Qbeta, complete genome http://www.ncbi.nlm.nih.gov/nuccore/NC_001890.1 Cite error: Invalid
<ref>tag; name "NC_001890.1" defined multiple times with different content - ↑ 3.0 3.1 Karnik, S & Billeter, M (1983) The lysis function of RNA bacteriophage Qbeta is mediated by the maturation (A2) protein. EMBO J. 2 1521-6 PubMed
- ↑ Bernhardt, TG et al. (2001) A protein antibiotic in the phage Qbeta virion: diversity in lysis targets. Science 292 2326-9 PubMed
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