Phage P2 Y:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

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Standard name

Y

Synonyms

P2p08

Product description

gpY; experimental evidence, no additional details recorded; holin; essential for host cell cell lysis

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology <protect> See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0044659

cytolysis by virus of host cell

PMID:23335412[1]

IMP: Inferred from Mutant Phenotype

P

Figure 2A,2B

complete

GO:0034290

holin activity

PMID:8051010[2]

IMP: Inferred from Mutant Phenotype

F

Figure 5, text on page 4981

complete

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Interactions <protect> See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

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Notes

Localization

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Compartment Description Evidence Reference/Source Notes

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Notes

Structure and Physical Properties

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<protect> Physical Properties <protect> See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence
MTAEEKSVLS LFMIGVLIVV GKVLAGGEPI TPRLFIGRML LGGFVSMVAG VVLVQFPDLS
LPAVCGIGSM LGIAGYQVIE IAIQRRFKGR GKQ
Length

93

Mol. Wt

9.817 kDa

pI

10.2 (calculated)

Extinction coefficient

1,490 - 1,615 (calc based on 1 Y, 0 W, and 1 C residues)

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Domains/Motifs/Modification Sites <protect> See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

10 - 27

Predicted membrane-spanning helix.

TMD predicted by TMHMM[3]

Domain

34 - 56

Predicted membrane-spanning helix.

TMD predicted by TMHMM[3]

Domain

61 - 83

Predicted membrane-spanning helix.

TMD predicted by TMHMM[3]


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Structure
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Structures

<beststructure> gene=Phage_P2_Y taxon=10679 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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<protect> See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. To, KH et al. (2013) Functional analysis of a class I holin, P2 Y. J. Bacteriol. 195 1346-55 PubMed
  2. Ziermann, R et al. (1994) Functions involved in bacteriophage P2-induced host cell lysis and identification of a new tail gene. J. Bacteriol. 176 4974-84 PubMed
  3. 3.0 3.1 3.2 Krogh, A et al. (2001) Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. J. Mol. Biol. 305 567-80 PubMed

Categories

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