Phage P1 lydA:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

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Standard name

LydA

Synonyms

gp027

Product description

holin; 100 pct identical to 109 aa long holin encoded by lydA gene of plasmid p15B PID:g421122; 30 pct identical to LydC holin of P1 encoded by the following gene;

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology <protect> See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0034290

holin activity

PMID:8576044[1]

IDA: Inferred from Direct Assay

F

Text on page 1103

complete

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Interactions <protect> See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence
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Notes

Localization

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Compartment Description Evidence Reference/Source Notes
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Notes

Structure and Physical Properties

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<protect> Physical Properties <protect> See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence 
MLDTQELAPV AIALLLSVIG GIGTFLMDVR DGRQSGNLLG LVTEIFVAVT AGAVAYLLGQ
HEGWELSITY LMVTIASNNG HEVISGMKRV NIDSILNVLT SLVKKGGGK
Length

109

Mol. Wt

11.466 kDa

pI

5.5 (calculated)

Extinction coefficient

8,480 (calc based on 2 Y, 1 W, and 0 C residues)

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Domains/Motifs/Modification Sites

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Type Residues Description Notes References

Domain

36 - 58

Predicted membrane-spanning helix.

TMD predicted by TMHMM[2]

Domain

7 - 26

Predicted membrane-spanning helix.

TMD predicted by TMHMM[2]


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<motif_map/>

tmhmm.php?gene=Phage_P1_lydA&show=pic&.jpg
Click the image to view raw output from TMHMM.

Structure
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Structures

<beststructure> gene=Phage_P1_lydA taxon=10678 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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<protect> See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes
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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ Schmidt, C et al. (1996) Three functions of bacteriophage P1 involved in cell lysis. J. Bacteriol. 178 1099-104 PubMed
  2. ↑ 2.0 2.1 Krogh, A et al. (2001) Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. J. Mol. Biol. 305 567-80 PubMed

Categories

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