Phage MS2 L:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

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Standard name

L

Synonyms

MS2g3

Product description

lysis protein

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology <protect> See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0019077

lytic viral release

PMID:498271[1]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0019077

lytic viral release

PMID:387256[2]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0019077

lytic viral release

PMID:498270[3]

IMP: Inferred from Mutant Phenotype

P

complete

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Interactions <protect> See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

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Notes

Localization

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Compartment Description Evidence Reference/Source Notes

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Notes

Structure and Physical Properties

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<protect> Physical Properties <protect> See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence
METRFPQQSQ QTPASTNRRR PFKHEDYPCR RQQRSSTLYV LIFLAIFLSK FTNQLLLSLL
EAVIRTVTTL QQLLT
Length

75

Mol. Wt

8.87 kDa

pI

11.3 (calculated)

Extinction coefficient

2,980 - 3,105 (calc based on 2 Y, 0 W, and 1 C residues)

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Domains/Motifs/Modification Sites

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See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

38 - 60

Predicted membrane-spanning helix.

TMD predicted by TMHMM[4]


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<motif_map/>

tmhmm.php?gene=Phage_MS2_L&show=pic&.jpg
Click the image to view raw output from TMHMM.

Structure
<protect> See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=Phage_MS2_L taxon=12022 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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<protect> See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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<protect> See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. Atkins, JF et al. (1979) Binding of mammalian ribosomes to MS2 phage RNA reveals an overlapping gene encoding a lysis function. Cell 18 247-56 PubMed
  2. Beremand, MN & Blumenthal, T (1979) Overlapping genes in RNA phage: a new protein implicated in lysis. Cell 18 257-66 PubMed
  3. Model, P et al. (1979) Characterization of Op3, a lysis-defective mutant of bacteriophage f2. Cell 18 235-46 PubMed
  4. Krogh, A et al. (2001) Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. J. Mol. Biol. 305 567-80 PubMed

Categories

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