dinF:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

DinF

Synonyms

DNA-damage-inducible SOS response protein[1], DNA-damage-inducible protein F[2][1], DinF[2][1], B4044[2][1]

Product description

DinF MATE Transporter[2][3]

Induced by UV and mitomycin C, function unknown[4]

EC number (for enzymes)


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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0015238

drug transporter activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002528

F

Seeded from EcoCyc [5]

complete

GO:0006855

multidrug transport

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002528

P

Seeded from EcoCyc [5]

complete

GO:0016021

integral to membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

Seeded from EcoCyc [5]

complete

GO:0015297

antiporter activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002528

F

Seeded from EcoCyc [5]

complete

GO:0016020

membrane

GO_REF:0000002
GO_REF:0000004
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR002528
SP_KW:KW-0397
SP_KW:KW-0472

C

Seeded from EcoCyc 12.5 [6]

complete

GO:0006281

DNA repair

P

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0005886

plasma membrane

GO_REF:0000004
GO_REF:0000004
GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_KW:KW-0997
SP_KW:KW-1003
SP_SL:SL-0037

C

Seeded from EcoCyc [5]

complete

GO:0015292

uniporter activity

F

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0009432

SOS response

P

Seeded from EcoCyc 11.1[3].

required fields missing

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Notes
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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence

at EcoCyc 

MPPGVAVCFS SLFIRLVCMA FLTSSDKALW HLALPMIFSN ITVPLLGLVD TAVIGHLDSP
VYLGGVAVGA TATSFLFMLL LFLRMSTTGL TAQAYGAKNP QALARTLVQP LLLALGAGAL
IALLRTPIID LALHIVGGSE AVLEQARRFL EIRWLSAPAS LANLVLLGWL LGVQYARAPV
ILLVVGNILN IVLDVWLVMG LHMNVQGAAL ATVIAEYATL LIGLLMVRKI LKLRGISGEM
LKTAWRGNFR RLLALNRDIM LRSLLLQLCF GAITVLGARL GSDIIAVNAV LMTLLTFTAY
ALDGFAYAVE AHSGQAYGAR DGSQLLDVWR AACRQSGIVA LLFSVVYLLA GEHIIALLTS
LTQIQQLADR YLIWQVILPV VGVWCYLLDG MFIGATRATE MRNSMAVAAA GFALTLLTLP
WLGNHALWLA LTVFLALRGL SLAAIWRRHW RNGTWFAAT
Length

459

Mol. Wt

49.65 kDa (calc) [2]

pI
Extinction coefficient

86400 - 87025 (calc based on 10 Y, 13 W, and 5 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes

Domain

259 - 281

Predicted membrane-spanning helix.

TMD predicted by TMHMM[7]

Domain

285 - 307

Predicted membrane-spanning helix.

TMD predicted by TMHMM[7]

Domain

339 - 361

Predicted membrane-spanning helix.

TMD predicted by TMHMM[7]

Domain

371 - 393

Predicted membrane-spanning helix.

TMD predicted by TMHMM[7]

Domain

406 - 423

Predicted membrane-spanning helix.

TMD predicted by TMHMM[7]

Domain

427 - 446

Predicted membrane-spanning helix.

TMD predicted by TMHMM[7]

Domain

5 - 22

Predicted membrane-spanning helix.

TMD predicted by TMHMM[7]

Domain

29 - 51

Predicted membrane-spanning helix.

TMD predicted by TMHMM[7]

Domain

61 - 83

Predicted membrane-spanning helix.

TMD predicted by TMHMM[7]

Domain

107 - 129

Predicted membrane-spanning helix.

TMD predicted by TMHMM[7]

Domain

149 - 171

Predicted membrane-spanning helix.

TMD predicted by TMHMM[7]

Domain

178 - 200

Predicted membrane-spanning helix.

TMD predicted by TMHMM[7]

Domain

205 - 227

Predicted membrane-spanning helix.

TMD predicted by TMHMM[7]

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tmhmm.php?gene=dinF&show=pic&.jpg
Click the image to view raw output from TMHMM.

Structure See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure>dinF 562</beststructure>

Models

View models at:

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:DINF-MONOMER

UniProt (EcoliWiki Page)

UniProt:P28303

PFAM (EcoliWiki Page)

PFAM:PF01554

RefSeq (EcoliWiki Page)

RefSeq:NP_418468


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Notes

Links

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Name URL Comments
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References

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  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 3.2 3.3 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 5.2 5.3 5.4 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
  6. ↑ EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  7. ↑ 7.00 7.01 7.02 7.03 7.04 7.05 7.06 7.07 7.08 7.09 7.10 7.11 7.12 Krogh, A et al. (2001) Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. J. Mol. Biol. 305 567-80 PubMed


Categories

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