yeaI:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

YeaI

Synonyms

predicted diguanylate cyclase[1], YeaI[2][1], B1785[2][1]

Product description

predicted diguanylate cyclase[2][3]

Probable diguanylate cyclase, function unknown[4]

EC number (for enzymes)


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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0016021

integral to membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

Seeded from EcoCyc 12.5 [5]

complete

GO:0016020

membrane

GO_REF:0000004
GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0397
SP_KW:KW-0472

C

Seeded from EcoCyc 12.5 [5]

complete

GO:0005886

plasma membrane

GO_REF:0000004
GO_REF:0000004
GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_KW:KW-0997
SP_KW:KW-1003
SP_SL:SL-0037

C

Seeded from EcoCyc [6]

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Notes

plasma membrane

C-terminus localized in the cytoplasm with 8 predicted transmembrane domains

Daley et al. (2005) [7]


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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence

at EcoCyc 

MIQSTRISMG LFFKYFLSLT KIDPGQNYIS LPSIKSSTHI ALLFMVSMGT QKLKAQSFFI
FSLLLTLILF CITTLYNENT NVKLIPQMNY LMVVVALFFL NAVIFLFMLM KYFTNKQILP
TLILSLAFLS GLIYLVETIV IIHKPINGST LIQTKSNDVS IFYIFRQLSF ICLTSLALFC
YGKDNILDNN KKKTGILLLA LIPFLVFPLL AHNLSSYNAD YSLYVVDYCP DNHTATWGIN
YTKILVCLWA FLLFFIIMRT RLASELWPLI ALLCLASLCC NLLLLTLDEY NYTIWYISRG
IEVSSKLFVV SFLIYNIFQE LQLSSKLAVH DVLTNIYNRR YFFNSVESLL SRPVVKDFCV
MLVDINQFKR INAQWGHRVG DKVLVSIVDI IQQSIRPDDI LARLEGEVFG LLFTELNSAQ
AKIIAERMRK NVELLTGFSN RYDVPEQMTI SIGTVFSTGD TRNISLVMTE ADKALREAKS
EGGNKVIIHH I
Mol. Wt

56.1 kDa (calc) [2]

pI
Extinction coefficient

57300 - 58425 (calc based on 20 Y, 5 W, and 9 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes

Domain

356 - 491

GGDEF

UniProt:P76236

Domain

121 - 143

Predicted membrane-spanning helix.

TMD predicted by TMHMM[8]

Domain

163 - 182

Predicted membrane-spanning helix.

TMD predicted by TMHMM[8]

Domain

195 - 214

Predicted membrane-spanning helix.

TMD predicted by TMHMM[8]

Domain

234 - 256

Predicted membrane-spanning helix.

TMD predicted by TMHMM[8]

Domain

263 - 285

Predicted membrane-spanning helix.

TMD predicted by TMHMM[8]

Domain

295 - 317

Predicted membrane-spanning helix.

TMD predicted by TMHMM[8]

Domain

58 - 77

Predicted membrane-spanning helix.

TMD predicted by TMHMM[8]

Domain

87 - 109

Predicted membrane-spanning helix.

TMD predicted by TMHMM[8]

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tmhmm.php?gene=yeaI&show=pic&.jpg
Click the image to view raw output from TMHMM.

Structure See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure>yeaI 562</beststructure>

Models

View models at:

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:G6971-MONOMER

UniProt (EcoliWiki Page)

UniProt:P76236

PFAM (EcoliWiki Page)

PFAM:PF00990

RefSeq (EcoliWiki Page)

RefSeq:NP_416299


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Notes

Links

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Name URL Comments
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References

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  1. ↑ 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  6. ↑ EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
  7. ↑ Daley, DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308 1321-3 PubMed
  8. ↑ 8.0 8.1 8.2 8.3 8.4 8.5 8.6 8.7 Krogh, A et al. (2001) Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. J. Mol. Biol. 305 567-80 PubMed


Categories

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