yicO:Quickview
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
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| Standard Name |
|---|
| Gene Synonym(s) |
| Product Desc. |
| Product Synonyms(s) |
| Knock-Out Phenotype |
| Regulation/Expression |
| Regulation/Activity |
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Notes
Paralogs YicO and PurP are 74% identical. PurP seems to account for all the high-affinity permease activity and it is unlikley that YicO is the low affinity activity, so YicO may need to be induced by BaeSR to get activity. yicO and the adajcent adenine deaminase gene ade may constitute an inducible adenine utilization divergon, however the convergent gene arrangement is not conserved outside of E. coli: the genes are adjacent in Klebsiella and Serratia in an apparent operon arrangement; this difference may reflect horizontal acquisition of ade, which is predicted to be an HT gene although yicO is a core gene, so their association may be a relatively recent evolutionary development. BaeSR regulon.[1]
References