yicO:Quickview
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
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| Standard Name |
yicO |
|---|---|
| Gene Synonym(s) |
ECK3655, b3664, JW5636[1], JW5636, pbuA |
| Product Desc. |
putative membrane protein with possible relationship to novobiocin and deoxycholate resistance[2][3] Probable adenine permease[4] |
| Product Synonyms(s) |
predicted xanthine/uracil permase[1], B3664[2][1], YicO[2][1] , ECK3655, JW5636, pbuA, b3664 |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
| Quick Links |
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Notes
Paralogs YicO and PurP are 74% identical. PurP seems to account for all the high-affinity permease activity and it is unlikley that YicO is the low affinity activity, so YicO may need to be induced by BaeSR to get activity. yicO and the adajcent adenine deaminase gene ade may constitute an inducible adenine utilization divergon, however the convergent gene arrangement is not conserved outside of E. coli: the genes are adjacent in Klebsiella and Serratia in an apparent operon arrangement; this difference may reflect horizontal acquisition of ade, which is predicted to be an HT gene although yicO is a core gene, so their association may be a relatively recent evolutionary development. BaeSR regulon.[4]
References
- ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
