marA:Quickview
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
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| Standard Name |
marA |
|---|---|
| Gene Synonym(s) |
ECK1524, b1531, JW5249, cfxB, norB, soxQ, inaR, nfxC[1] |
| Product Desc. |
MarA transcriptional activator[2]; MarA transcriptional dual regulator[3] Transcriptional activator for multiple antibiotic resistance; AraC family; resistance to tetracycline, chloramphenicol[4] |
| Product Synonyms(s) |
DNA-binding transcriptional dual activator of multiple antibiotic resistance[1], B1531[2][1], CfxB[2][1], InaR[2][1], NorB[2][1], SoxQ[2][1], NfxC[2][1], MarA[2][1] |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity |
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Notes
Martin (2002) provide some evidence in support of the this alternative ATG start: native protein is slightly smaller than the engineered protein by Western blot. The spacing to the GAGG RBS is bad for the first ATG and excellent for the second ATG. MarA is unstable.[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.