cspE:Quickview

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Gene Name

cspE (synonyms: ECK0616, b0623, JW0618, gicA, msmC)[1]

Product(s)

CspE product[1]: DNA-binding transcriptional repressor product, B0623 product, MsmC product, GicA product

Description

cold shock protein CspE[2] transcription antiterminator and regulator of RNA stability[3]

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): cspE[2]

Regulation/Activity


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Notes

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The cspABEG deletion BX04 is cold-sensitive and forms filaments at 15C (Xia, 2001). CspE is a cold shock protein homolog, but is constitutively expressed at 37C. CspE has transcription antitermination activity. CspE affects rpoS and uspA expression. CspE is a negative regulator of cspA transcription. CspE binds ssDNA containing six or more contiguous dT residues with high affinity (Johnston, 2006).[4]



References

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  1. ↑ 1.0 1.1 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.