cspE:Quickview
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Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
References | Suggestions |
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Standard Name |
cspE |
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Gene Synonym(s) |
ECK0616, b0623, JW0618, gicA, msmC[1], msmC |
Product Desc. |
cold shock protein CspE[2]; transcription antiterminator and regulator of RNA stability[3] Binds and melts RNA, involved in cold acclimation; binds ssDNA; high copy protects the chromosome from decondensation by camphor and increases DNA supercoiling; dimeric[4] |
Product Synonyms(s) |
DNA-binding transcriptional repressor[1], B0623[2][1], MsmC[2][1], GicA[2][1], CspE[2][1] , ECK0616, gicA, JW0618, msmC, b0623 |
Function from GO |
<GO_nr /> |
Knock-Out Phenotype | |
Regulation/Expression | |
Regulation/Activity | |
Quick Links | |
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Notes
The cspABEG deletion BX04 is cold-sensitive and forms filaments at 15C (Xia, 2001). CspE is a cold shock protein homolog, but is constitutively expressed at 37C. CspE has transcription antitermination activity. CspE affects rpoS and uspA expression. CspE is a negative regulator of cspA transcription. CspE binds ssDNA containing six or more contiguous dT residues with high affinity (Johnston, 2006).[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.