nuoC:Quickview

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Gene Name

nuoC (synonyms: ECK2280, b2286, JW5375, nuoCD, nuoD)[1]

Product(s)

NuoC product[1]: NADH:ubiquinone oxidoreductase, chain C,D product, B2286 product, NuoD product, NuoCD product

Description

NuoC[2][3]

Component of connecting fragment of NADH dehydrogenase I[3],NADH dehydrogenase I[2]

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): nuoABCEFGHIJKLMN[2], nuo1-14

Regulation/Activity


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Notes

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Leif (1995) find the starting amino acids at codon +4 (MVNN), in conflict with the more recent data of David (2002), which does not include these 4 amino acids and the initial Met. Alignment with Yersinia NuoC supports the second ATG annotated here. The reason for the discrepancy is not known as both used native protein preparations, although the protein band sequenced by Leif et al. was not the correct MW for the revised, fused NuoCD protein sequence. HT_Cmplx18_Mem: NuoB+NuoC.[4]



References

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  1. ↑ 1.0 1.1 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.