tonB:Quickview

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Gene Name

tonB (synonyms: ECK1246, b1252, JW5195, T1rec, exbA)[1]

Product(s)

TonB product[1]: membrane spanning protein in TonB-ExbB-ExbD complex product, B1252 product, ExbA product

Description

TonB protein; energy transducer; uptake of iron, cyanocobalimin; sensitivity to phages, colicins[2][3]

Component of TonB energy transducing system[3],Outer Membrane Ferric Citrate Transport System[3],Outer Membrane Ferrichrome Transport System[3],Outer Membrane Ferric Enterobactin Transport System[3],vitamin B12 outer membrane transport complex[3],ferric dicitrate uptake system[3],ferrichrome uptake system[3],Ferric Enterobactin Transport System[3],vitamin B12 transport system[3]

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): tonB[2], OP00228

Regulation/Activity


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Notes

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Periplasmic TonB is anchored to the cytoplasmic membrane by a signal anchor and interacts with outer membrane proteins, thus TonB spans the periplasmic space. TonB contains 40 proline residues (17%).[4]



References

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  1. ↑ 1.0 1.1 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.00 3.01 3.02 3.03 3.04 3.05 3.06 3.07 3.08 3.09 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.