fadR:Quickview

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Gene Name

fadR (synonyms: ECK1175, b1187, JW1176, dec, ole, thdB, oleR)[1]

Product(s)

FadR product[1]: DNA-binding transcriptional dual regulator of fatty acid metabolism product, B1187 product, Ole product, Dec product, ThdB product, OleR product, negative regulator for fad regulon, and positive activator of fabA product

Description

FadR transcriptional dual regulator[2][3]

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): fadR[2]

Regulation/Activity


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Notes

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The fad genes are induced and fabAB, iclR are repressed by long chain acyl-CoA thioesters binding to and releasing FadR from the DNA. FadR is a GntR-type DNA-binding transcriptional regulator.[4]



References

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  1. ↑ 1.0 1.1 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.