cbl:Gene Product(s)

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Structure Resources Accessions Links References Suggestions

Nomenclature

Standard name

Cbl product

Synonyms

DNA-binding transcriptional activator of cysteine biosynthesis product[1], B1987 product[2][1], Cbl product[2][1]

Product description

Cbl transcriptional activator[2][3]

EC number (for enzymes)
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Notes

Function

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Gene Ontology

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status

NOT

GO:0006790

sulfur metabolic process

PMID:10506196[4]

IDA: Inferred from Direct Assay

P

Seeded from EcoCyc 11.1[3].

This is not part of the sulfur metabolic process. See below for the regulation of sulfur metabolism

complete

GO:0006350

transcription

PMID:10506196[4]

IDA: Inferred from Direct Assay

P

Seeded from EcoCyc 11.1[3].

complete

NOT

GO:0019344

cysteine biosynthetic process

PMID:10506196[4]

P

Seeded from EcoCyc 11.1[3].

required field missing

GO:0016564

transcription repressor activity

F

Seeded from EcoCyc 10.6[2].

required fields missing

GO:0005737

cytoplasm

C

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0016563

transcription activator activity

PMID:10506196[4]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc 11.1[3].

complete

GO:0045883

positive regulation of sulfur utilization

PMID:10506196[4]

IDA: Inferred from Direct Assay

P

complete

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Interactions

Partner Type Partner Notes
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Notes

Localization

Compartment Description Evidence Notes
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Notes

Structure and Physical Properties

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Physical Properties

Sequence

at EcoCyc 

MNFQQLKIIR EAARQDYNLT EVANMLFTSQ SGVSRHIREL EDELGIEIFV RRGKRLLGMT
EPGKALLVIA ERILNEASNV RRLADLFTND TSGVLTIATT HTQARYSLPE VIKAFRELFP
EVRLELIQGT PQEIATLLQN GEADIGIASE RLSNDPQLVA FPWFRWHHSL LVPHDHPLTQ
ISPLTLESIA KWPLITYRQG ITGRSRIDDA FARKGLLADI VLSAQDSDVI KTYVALGLGI
GLVAEQSSGE QEEENLIRLD TRHLFDANTV WLGLKRGQLQ RNYVWRFLEL CNAGLSVEDI
KRQVMESSEE EIDYQI
Mol. Wt

35.86 kDa (calc) [2]

pI
Extinction coefficient

36440 - 36565 (calc based on 6 Y, 5 W, and 1 C residues)

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Domains/Motifs/Modification Sites

Type Residues Description Notes
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Structure

Structure Type Organism Accession Residues covered Notes
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Notes

Gene Product Resources

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Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:G7071-MONOMER

SwissModel (EcoliWiki Page)

SwissModel:Q47083

UniProt (EcoliWiki Page)

UniProt:Q47083

PFAM (EcoliWiki Page)

PFAM:PF00126

RefSeq (EcoliWiki Page)

RefSeq:NP_416492

ModBase (EcoliWiki Page)

ModBase:Q47083

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Notes

Links

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Name URL Comments
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References

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  1. ↑ 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 3.2 3.3 3.4 3.5 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 4.2 4.3 4.4 van Der Ploeg, JR et al. (1999) The Escherichia coli ssuEADCB gene cluster is required for the utilization of sulfur from aliphatic sulfonates and is regulated by the transcriptional activator Cbl. J. Biol. Chem. 274 29358-65 PubMed


Categories

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