Phage PRD1
Bacteriophage f1 is structurally classified as a class I filamentous phage, and is closely related to the other Ff phages, Phage M13 and phage fd. [1] [2]
The full sequence is available from NCBI at GenBank: J02448.1
This page is currently under construction, and much of the information is currently just a placeholder- it may not apply to PRD1 at all.
Morphology
Genome Organization
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f1 has a circular, 6407 bp genome of ss-DNA.
There are 11 genes encoded on the genome; two are overlapping in-frame genes. Five of the encoded proteins make up the viron, three are needed for synthesis and the rest are for assembly. [3] The genes are generally referred to by Roman numerals I-XI as listed on the Phage f1 page. Genes are in the order II (X), V, VII, IX, VIII, III, VI, I (XI), IV, intergenic region (IG or IGR). [1] The IGR contains the packing signal (PS) as well as sequences that dictate termination, nicking for replication, and the binding of protein II and IHF. [1]
Life cycle
Adsorption and Injection
DNA replication
Packaging
Lysis
See also
- Phage f1 Gene List
- Phage M13
- J02448 on NCBI
- Phage f1 taxonomy on NCBI
- International Committee on Taxonomy of Viruses
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 Edited by Richard Calendar (2006) The Bacteriophages (Oxford University Press, Oxford, NY) ISBN 0-19-514850-9
- ↑ Lubkowski, J et al. (1999) Filamentous phage infection: crystal structure of g3p in complex with its coreceptor, the C-terminal domain of TolA. Structure 7 711-22 PubMed
- ↑ Russel, M et al. (1997) Filamentous phage assembly: variation on a protein export theme. Gene 192 23-32 PubMed