ftsL:Expression

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Overview Transcription Translation Turnover Experimental Links References Suggestions

Overview

This is a placeholder for a summary statement on how expression of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.


Cellular Levels

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See Help:Cellular levels

Molecule Organism or Strain Value Units Experimental Conditions Assay used Notes Reference(s)

Protein

E. coli LMG83, LMG145, LMG142 (see table 1)

20 - 40

molecules/cell

  • Medium: NZY (rich media, recipe described on page 7717)
  • Temperature (°C): 37
  • Growth Rate(min):
  • other:

enzyme activity

A chromosomal FtsL-phoA (alkaline phosphatase) fusion was assayed for AP activity & shown to be relatively comparable to the previously reported activity/concentration of FtsQ-phoA estimated at 20-40 molecules per cell (reported by Carson et al., PMID:2007547[1]).

PMID:1332942[2]

Notes

Transcription and Transcriptional Regulation

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See Help:Expression_transcription for help entering or editing information in this section of EcoliWiki.

Transcription unit(s)

mraZW-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ

Figure courtesy of RegulonDB


Notes

This is a placeholder for a summary statement about how transcription of this gene is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Periplasmic domain integrity is essential for FtsL to perform accurately. [3]

Translation and Regulation of Translation

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<gbrowseImage> name=NC_000913:91012..91052 source=MG1655 type=Gene+DNA_+Protein preset=Nterminus </gbrowseImage> This picture shows the sequence around the N-terminus.


Notes

This is a placeholder for a summary statement about how translation of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Turnover and Regulation of Turnover

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Notes

This is a placeholder for a summary statement about turnover of this gene product. You can help EcoliWiki by becoming a user and writing/editing this statement.

Experimental

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Mutations Affecting Expression See Help:Expression_mutations for help entering or editing information in this section of EcoliWiki.

Allele Name Mutation Phenotype Reference


Expression Studies See Help:Expression_studies for help entering or editing information in this section of EcoliWiki.

Type Reference Notes

microarray

GEO Profiles:b0083 (EcoliWiki Page)

NCBI GEO profiles for ftsL

microarray

GenExpDB:b0083 (EcoliWiki Page)

Summary of data for ftsL from multiple microarray studies


Expression Resources See Help:Expression_resources for help entering or editing information in this section of EcoliWiki.

Resource Name Resource Type Description Source Notes

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Notes

Accessions Related to ftsL Expression

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:EG11086

EchoBASE (EcoliWiki Page)

EchoBASE:EB1078

EcoliGenExpDB (EcoliWiki Page)

EcoliGenExpDB:b0083

EcoGene (EcoliWiki Page)

EcoGene:EG11086



Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ Carson, MJ et al. (1991) The FtsQ protein of Escherichia coli: membrane topology, abundance, and cell division phenotypes due to overproduction and insertion mutations. J. Bacteriol. 173 2187-95 PubMed
  2. ↑ Guzman, LM et al. (1992) FtsL, an essential cytoplasmic membrane protein involved in cell division in Escherichia coli. J. Bacteriol. 174 7716-28 PubMed
  3. ↑ Ghigo, JM & Beckwith, J (2000) Cell division in Escherichia coli: role of FtsL domains in septal localization, function, and oligomerization. J. Bacteriol. 182 116-29 PubMed

Categories

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