DNA Replication

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General Description

Components

Function

Regulation

Cell Biology

Replication of the circular E.coli chromosome occurs bidirectionally from oriC.

There are several models for replication:

After replication, the daughter chromosomes must be segregated using various mechanisms.

Experimental Resources

Comparison with other organisms

Notes

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References

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  1. ↑ Dingman, CW (1974) Bidirectional chromosome replication: some topological considerations. J. Theor. Biol. 43 187-95 PubMed
  2. ↑ Lemon, KP & Grossman, AD (1998) Localization of bacterial DNA polymerase: evidence for a factory model of replication. Science 282 1516-9 PubMed
  3. ↑ Lemon, KP & Grossman, AD (2000) Movement of replicating DNA through a stationary replisome. Mol. Cell 6 1321-30 PubMed
  4. ↑ Lemon, KP & Grossman, AD (2001) The extrusion-capture model for chromosome partitioning in bacteria. Genes Dev. 15 2031-41 PubMed