hofQ:Gene Product(s)

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

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Standard name

HofQ

Synonyms

predicted fimbrial transporter[1], B3391[2][1], HopQ[2][1], HofQ[2][1]

Product description

protein involved in utilization of DNA as a carbon source[2][3]

Required for the utilization of DNA as a carbon source; H. influenzae competence protein ComE homolog; putative fimbrial transport protein; expression not detected[4]

EC number (for enzymes)


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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0006810

transport

PMID:19011021[5]

IDA: Inferred from Direct Assay

P

complete

GO:0008565

protein transporter activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004845

F

Seeded from EcoCyc [6]

complete

GO:0009297

pilus formation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR013355

P

Seeded from EcoCyc [6]

complete

GO:0009306

protein secretion

GO_REF:0000002
GO_REF:0000002
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001775
InterPro:IPR004846
InterPro:IPR013355

P

Seeded from EcoCyc [6]

complete

GO:0016020

membrane

PMID:19011021[5]

IDA: Inferred from Direct Assay

C

complete

GO:0019867

outer membrane

GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR011662
SP_KW:KW-0557

C

Seeded from EcoCyc 12.5 [7]

complete

GO:0015976

carbon utilization

P

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0005886

plasma membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-1003

C

Seeded from EcoCyc [6]

complete

GO:0009279

cell outer membrane

GO_REF:0000004
GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_KW:KW-0998
SP_SL:SL-0040

C

Seeded from EcoCyc [6]

complete

GO:0015978

carbon utilization by utilization of organic compounds

PMID:16707682[8]

IMP: Inferred from Mutant Phenotype

P

Seeded from EcoCyc [6]

complete

GO:0003677

DNA binding

PMID:19011021[5]

IDA: Inferred from Direct Assay

F

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

ahpC

PMID:16606699[9]

Experiment(s):EBI-1145783

Protein

rpsD

PMID:16606699[9]

Experiment(s):EBI-1145783

Protein

ybfC

PMID:16606699[9]

Experiment(s):EBI-1145783

Protein

hflK

PMID:16606699[9]

Experiment(s):EBI-1145783

Protein

rplC

PMID:16606699[9]

Experiment(s):EBI-1145783

Protein

iscS

PMID:16606699[9]

Experiment(s):EBI-1145783
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Source Notes
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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence

at EcoCyc 

MKQWIAALLL MLIPGVQAAK PQKVTLMVDD VPVAQVLQAL AEQEKLNLVV SPDVSGTVSL
HLTDVPWKQA LQTVVKSAGL ITRQEGNILS VHSIAWQNNN IARQEAEQAR AQANLPLENR
SITLQYADAG ELAKAGEKLL SAKGSMTVDK RTNRLLLRDN KTALSALEQW VAQMDLPVGQ
VELSAHIVTI NEKSLRELGV KWTLADAQHA GGVGQVTTLG SDLSVATATT HVGFNIGRIN
GRLLDLELSA LEQKQQLDII ASPRLLASHL QPASIKQGSE IPYQVSSGES GATSVEFKEA
VLGMEVTPTV LQKGRIRLKL HISQNVPGQV LQQADGEVLA IDKQEIETQV EVKSGETLAL
GGIFTRKNKS GQDSVPLLGD IPWFGQLFRH DGKEDERREL VVFITPRLVS SE
Length

412

Mol. Wt

44.715 kDa

pI

6.5 (calculated)

Extinction coefficient

35,980 (calc based on 2 Y, 6 W, and C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

motif

1-18

UniProt Manual:Signal Peptides

UniProt:P34749


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<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=hofQ taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:EG12113-MONOMER

UniProt (EcoliWiki Page)

UniProt:P34749

PFAM (EcoliWiki Page)

PFAM:PF07660

RefSeq (EcoliWiki Page)

RefSeq:NP_417850

ECOO157CYC (EcoliWiki Page)

ECOO157CYC:HOFQ-MONOMER


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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 5.2 Sun, D et al. (2009) Transforming DNA uptake gene orthologs do not mediate spontaneous plasmid transformation in Escherichia coli. J. Bacteriol. 191 713-9 PubMed
  6. ↑ 6.0 6.1 6.2 6.3 6.4 6.5 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
  7. ↑ EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  8. ↑ Palchevskiy, V & Finkel, SE (2006) Escherichia coli competence gene homologs are essential for competitive fitness and the use of DNA as a nutrient. J. Bacteriol. 188 3902-10 PubMed
  9. ↑ 9.0 9.1 9.2 9.3 9.4 9.5 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed

Categories

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