lnt:Gene Product(s)

Standard name	Lnt
Synonyms	apolipoprotein N-acyltransferase^[1], B0657^[2]^[1], CutE^[2]^[1], Lnt^[2]^[1]
Product description	apolipoprotein N-acyltransferase^[2]^[3] Apolipoprotein N-acetyltransferase; copper sensitivity^[4]
EC number (for enzymes)	2.3.1.-^[1]
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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier	GO ID	GO term name	Reference(s)	Evidence Code	with/from	Aspect	Notes	Status
	GO:0042158	lipoprotein biosynthetic process	GO_REF:0000002 GO_REF:0000020	IEA: Inferred from Electronic Annotation	InterPro:IPR004563 HAMAP:MF_01148	P	Seeded from EcoCyc 12.5 ^[5]	complete
	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR003010	F	Seeded from EcoCyc ^[6]	complete
	GO:0016740	transferase activity	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0808	F	Seeded from EcoCyc ^[6]	complete
	GO:0016410	N-acyltransferase activity	GO_REF:0000002 GO_REF:0000020	IEA: Inferred from Electronic Annotation	InterPro:IPR004563 HAMAP:MF_01148	F	Seeded from EcoCyc 12.5 ^[5]	complete
	GO:0016021	integral to membrane	GO_REF:0000002 GO_REF:0000004	IEA: Inferred from Electronic Annotation	InterPro:IPR004563 SP_KW:KW-0812	C	Seeded from EcoCyc ^[6]	complete
	GO:0016020	membrane	GO_REF:0000004 GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0397 SP_KW:KW-0472	C	Seeded from EcoCyc 12.5 ^[5]	complete
	GO:0008415	acyltransferase activity	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0012	F	Seeded from EcoCyc ^[6]	complete
	GO:0006807	nitrogen compound metabolic process	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR003010	P	Seeded from EcoCyc ^[6]	complete
	GO:0005507	copper ion binding	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0186	F	Seeded from EcoCyc ^[6]	complete
	GO:0005886	plasma membrane	GO_REF:0000020 GO_REF:0000004 GO_REF:0000004 GO_REF:0000023	IEA: Inferred from Electronic Annotation	HAMAP:MF_01148 SP_KW:KW-0997 SP_KW:KW-1003 SP_SL:SL-0037	C	Seeded from EcoCyc ^[6]	complete
	GO:0005507	copper ion binding	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0186	F	Seeded from EcoCyc	complete
	GO:0005886	plasma membrane	GO_REF:0000020 GO_REF:0000004 GO_REF:0000004 GO_REF:0000023	IEA: Inferred from Electronic Annotation	HAMAP:MF_01148 SP_KW:KW-0997 SP_KW:KW-1003 SP_SL:SL-0037	C	Seeded from EcoCyc	complete
	GO:0006807	nitrogen compound metabolic process	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR003010	P	Seeded from EcoCyc	complete
	GO:0008415	acyltransferase activity	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0012	F	Seeded from EcoCyc	complete
	GO:0016020	membrane	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0472	C	Seeded from EcoCyc	complete
	GO:0016021	integral to membrane	GO_REF:0000002 GO_REF:0000004	IEA: Inferred from Electronic Annotation	InterPro:IPR004563 SP_KW:KW-0812	C	Seeded from EcoCyc	complete
	GO:0016410	N-acyltransferase activity	GO_REF:0000020 GO_REF:0000002	IEA: Inferred from Electronic Annotation	HAMAP:MF_01148 InterPro:IPR004563	F	Seeded from EcoCyc	complete
	GO:0016740	transferase activity	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0808	F	Seeded from EcoCyc	complete
	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR003010	F	Seeded from EcoCyc	complete
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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type	Partner	Notes	References	Evidence
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment	Description	Evidence	Notes
plasma membrane			From EcoCyc^[3]
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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence	at EcoCyc MAFASLIERQ RIRLLLALLF GACGTLAFSP YDVWPAAIIS LMGLQALTFN RRPLQSAAIG FCWGFGLFGS GINWVYVSIA TFGGMPGPVN IFLVVLLAAY LSLYTGLFAG VLSRLWPKTT WLRVAIAAPA LWQVTEFLRG WVLTGFPWLQ FGYSQIDGPL KGLAPIMGVE AINFLLMMVS GLLALALVKR NWRPLVVAVV LFALPFPLRY IQWFTPQPEK TIQVSMVQGD IPQSLKWDEG QLLNTLKIYY NATAPLMGKS SLIIWPESAI TDLEINQQPF LKALDGELRD KGSSLVTGIV DARLNKQNRY DTYNTIITLG KGAPYSYESA DRYNKNHLVP FGEFVPLESI LRPLAPFFDL PMSSFSRGPY IQPPLSANGI ELTAAICYEI ILGEQVRDNF RPDTDYLLTI SNDAWFGKSI GPWQHFQMAR MRALELARPL LRSTNNGITA VIGPQGEIQA MIPQFTREVL TTNVTPTTGL TPYARTGNWP LWVLTALFGF AAVLMSLRQR RK
Length	512
Mol. Wt	57.07 kDa (calc) ^[2]
pI
Extinction coefficient	113330 - 113705 (calc based on 17 Y, 16 W, and 3 C residues)
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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type	Residues	Description	Notes
Domain	222 - 512	CN hydrolase	UniProt:P23930
Domain	166 - 188	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[7]
Domain	195 - 213	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[7]
Domain	489 - 507	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[7]
Domain	54 - 76	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[7]
Domain	89 - 111	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[7]
Domain	12 - 34	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[7]
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<motif_map/>

Click the image to view raw output from TMHMM.

Structure See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

Models

View models at:

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type	Source	Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database	Accession	Notes
EcoCyc (EcoliWiki Page)	EcoCyc:EG10168-MONOMER
UniProt (EcoliWiki Page)	UniProt:P23930
PFAM (EcoliWiki Page)	PFAM:PF00795
RefSeq (EcoliWiki Page)	RefSeq:NP_415190
ModBase (EcoliWiki Page)	ModBase:P23930
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Notes

Links

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Name	URL	Comments
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References

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↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ ^3.0 ^3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
↑ ^5.0 ^5.1 ^5.2 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ ^6.0 ^6.1 ^6.2 ^6.3 ^6.4 ^6.5 ^6.6 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
↑ ^7.0 ^7.1 ^7.2 ^7.3 ^7.4 ^7.5 Krogh, A et al. (2001) Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. J. Mol. Biol. 305 567-80 PubMed

lnt:Gene Product(s)

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

Links

References

Categories

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lnt:Gene Product(s)

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

Links

References

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