metB:Gene Product(s)
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| Nomenclature | Function | Interactions | Localization | Sequence | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
| Standard name |
MetB product |
|---|---|
| Synonyms |
cystathionine gamma-synthase, PLP-dependent product[1], B3939 product[2][1], MetB product[2][1] |
| Product description |
Component of ; O-SUCCHOMOSERLYASE-CPLX[2] |
| EC number (for enzymes) | |
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See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
Notes
Function
Gene Ontology
| Qualifier | GO ID | GO term name | Reference(s) | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005737 |
cytoplasm |
C |
Seeded from EcoCyc 11.1[3]. |
required fields missing | ||||
| GO:0009063 |
amino acid catabolic process |
P |
Seeded from EcoCyc 11.1[3]. |
required fields missing | ||||
| GO:0009086 |
methionine biosynthetic process |
P |
Seeded from EcoCyc 11.1[3]. |
required fields missing | ||||
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See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
Interactions
| Partner Type | Partner | Notes |
|---|---|---|
|
Protein |
Subunits of O-SUCCHOMOSERLYASE-CPLX |
could be indirect |
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Notes
metB1 is a mutant brought about by X-ray mutagenesis and is most likely a deletion mutation.
The metB1 mutation causes a requirement for methionine and produces no enzymatic activity. [4]
Localization
| Compartment | Description | Evidence | Notes |
|---|---|---|---|
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See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
Notes
Structure and Physical Properties
Physical Properties
| Sequence |
MTRKQATIAV RSGLNDDEQY GCVVPPIHLS STYNFTGFNE PRAHDYSRRG NPTRDVVQRA LAELEGGAGA VLTNTGMSAI HLVTTVFLKP GDLLVAPHDC YGGSYRLFDS LAKRGCYRVL FVDQGDEQAL RAALAEKPKL VLVESPSNPL LRVVDIAKIC HLAREVGAVS VVDNTFLSPA LQNPLALGAD LVLHSCTKYL NGHSDVVAGV VIAKDPDVVT ELAWWANNIG VTGGAFDSYL LLRGLRTLVP RMELAQRNAQ AIVKYLQTQP LVKKLYHPSL PENQGHEIAA RQQKGFGAML SFELDGDEQT LRRFLGGLSL FTLAESLGGV ESLISHAATM THAGMAPEAR AAAGISETLL RISTGIEDGE DLIADLENGF RAANKG |
|---|---|
| Mol. Wt |
41.55 kDa (calc) [2] |
| pI |
6.43[2] |
| Extinction coefficient |
25900 - 26525 (calc based on 10 Y, 2 W, and 5 C residues) |
| edit table | |
See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
Domains/Motifs/Modification Sites
| Type | Residues | Description | Notes |
|---|---|---|---|
| edit table |
See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
Structure
| Structure Type | Organism | Accession | Residues covered | Notes |
|---|---|---|---|---|
| edit table |
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.
Notes
Gene Product Resources
| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
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Notes
Accessions in Other Databases
| Database | Accession | Notes |
|---|---|---|
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See Help:Product_accessions for help entering or editing information in this section of EcoliWiki.
Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
See Help:Links_table for how to enter or edit information in this section of EcoliWiki.
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 3.2 3.3 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ Hall, BG (1989) Selection, adaptation, and bacterial operons. Genome 31 265-71 PubMed
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