SOS Response

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General Description

A set of reversible checkpoints induced upon DNA damage, or regions of single stranded DNA.

Components

• LexA
• RecA
• SulA (a.k.a. SfiA)

Cell Biology

The expression of multiple genes is upregulated upon induction of the SOS response:

• sulA
• ftsK

Experimental Resources

Several antibiotics induce the SOS response

• mitomycin C (working concentration-0.1 µg/ml)

Notes

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References

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