nei:Gene Product(s): Difference between revisions

From EcoliWiki
Jump to navigation Jump to search
← Older editNewer edit →
Update TableEdit tables.
Line 35: Line 35:
*  
*  
****************************************************************************************** -->{{Product_nomenclature_help}}
****************************************************************************************** -->{{Product_nomenclature_help}}
{|border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  
{| id="L46aa3ee51966e" class=" tableEdit Product_nomenclature_table"


|-
|-
!align=left {{table heading style}} |Standard name
!align=left |Standard name
||
||
Nei  
Nei  
|-
|-
!align=left {{table heading style}} |Synonyms
!align=left |Synonyms
||
||
endonuclease VIII<ref name='LIB:Riley_2006'/>, 5-formyluracil/5-hydroxymethyluracil DNA glycosylase<ref name='LIB:Riley_2006'/>, B0714<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Nei<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
endonuclease VIII<ref name='LIB:Riley_2006'/>, 5-formyluracil/5-hydroxymethyluracil DNA glycosylase<ref name='LIB:Riley_2006'/>, B0714<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Nei<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
|-
|-
!align=left {{table heading style}} |Product description
!align=left |Product description
||
||
endonuclease VIII<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
endonuclease VIII<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
Line 52: Line 52:
DNA glycosylase/apurinic lyase, deoxyinosine-specific; endonuclease VIII<ref name='LIB:EcoGene'/>
DNA glycosylase/apurinic lyase, deoxyinosine-specific; endonuclease VIII<ref name='LIB:EcoGene'/>
|-
|-
!align=left {{table heading style}} |EC number (for enzymes)
!align=left |EC number (for enzymes)
||
||
* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.-.- 3.2.-.-]<ref name='LIB:Riley_2006'/>
* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.-.- 3.2.-.-]<ref name='LIB:Riley_2006'/>


|-class='sortbottom'
|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21183.L46aa3ee51966e&page=21183&pagename={{FULLPAGENAMEE}}&type=1&template=Product_nomenclature_table edit table] ||
|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21183.L46aa3ee51966e&page=21183&pagename={{FULLPAGENAMEE}}&type=1&template=Product_nomenclature_table edit table]</span> ||
|}
|}
<!--box uid=421aa90e079fa326b6494f812ad13e79.21183.L46aa3ee51966e-->
<!--box uid=421aa90e079fa326b6494f812ad13e79.21183.L46aa3ee51966e-->
Line 75: Line 75:
*  
*  
****************************************************************************************** -->{{Product_GO_help}}
****************************************************************************************** -->{{Product_GO_help}}
{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"   
{|   id="H46aa3ee6140ce" class=" tableEdit GO_table_product dataTable"   
|- {{table_heading_style}}
|-
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-  
|-  
Line 554: Line 554:
complete  
complete  


|-class='sortbottom'
|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21183.H46aa3ee6140ce&page=21183&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table] || || || || || || || ||
|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21183.H46aa3ee6140ce&page=21183&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table]</span> || || || || || || || ||
|}
|}
<!--box uid=421aa90e079fa326b6494f812ad13e79.21183.H46aa3ee6140ce-->
<!--box uid=421aa90e079fa326b6494f812ad13e79.21183.H46aa3ee6140ce-->
Line 567: Line 567:
*  
*  
****************************************************************************************** -->{{Product_interactions_help}}
****************************************************************************************** -->{{Product_interactions_help}}
{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"   
{|   id="J46aa3ef0582ce" class=" tableEdit Product_interactions_table"   
|- {{table heading style}}
|-
!|Partner Type!!Partner!!Notes!!References!!Evidence
!|Partner Type!!Partner!!Notes!!References!!Evidence
|-  
|-  
Line 758: Line 758:
Binding assay  
Binding assay  


|-class='sortbottom'
|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21183.J46aa3ef0582ce&page=21183&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table] || || || ||
|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21183.J46aa3ef0582ce&page=21183&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table]</span> || || || ||
|}
|}
<!--box uid=421aa90e079fa326b6494f812ad13e79.21183.J46aa3ef0582ce-->
<!--box uid=421aa90e079fa326b6494f812ad13e79.21183.J46aa3ef0582ce-->
Line 775: Line 775:
*  
*  
****************************************************************************************** -->{{Product_localization_help}}
****************************************************************************************** -->{{Product_localization_help}}
{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"   
{|   id="I46a7d09e14d71" class=" tableEdit Product_localization_table"   
|- {{table heading style}}
|-
!|Compartment!!Description!!Evidence!!Source!!Notes
!|Compartment!!Description!!Evidence!!Source!!Notes


|-class='sortbottom'
|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21183.I46a7d09e14d71&page=21183&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table] || || || ||
|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21183.I46a7d09e14d71&page=21183&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table]</span> || || || ||
|}
|}
<!--box uid=421aa90e079fa326b6494f812ad13e79.21183.I46a7d09e14d71-->
<!--box uid=421aa90e079fa326b6494f812ad13e79.21183.I46a7d09e14d71-->
Line 800: Line 800:
*  
*  
****************************************************************************************** -->{{Product_physical_properties_help}}
****************************************************************************************** -->{{Product_physical_properties_help}}
{|border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  
{| id="G46aa3ef21959a" class=" tableEdit Product_phys_prop_table"


|-
|-
!align=left {{table heading style}} |Sequence
!align=left |Sequence
||
||
[http://biocyc.org/ECOLI/sequence-aa?object=G6383-MONOMER at EcoCyc]  
[http://biocyc.org/ECOLI/sequence-aa?object=G6383-MONOMER at EcoCyc]  
Line 812: Line 812:
CGSIIEKTTL SSRPFYWCPG CQH</pre>  
CGSIIEKTTL SSRPFYWCPG CQH</pre>  
|-
|-
!align=left {{table heading style}} |Length
!align=left |Length
||
||
263
263
|-
|-
!align=left {{table heading style}} |Mol. Wt
!align=left |Mol. Wt
||
||
29.845 kDa
29.845 kDa
|-
|-
!align=left {{table heading style}} |pI
!align=left |pI
||
||
8.0 (calculated)
8.0 (calculated)
|-
|-
!align=left {{table heading style}} |Extinction coefficient
!align=left |Extinction coefficient
||
||
32,430 - 32,930 (calc based on 7 Y, 4 W, and 4 C residues)
32,430 - 32,930 (calc based on 7 Y, 4 W, and 4 C residues)


|-class='sortbottom'
|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21183.G46aa3ef21959a&page=21183&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table] ||
|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21183.G46aa3ef21959a&page=21183&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table]</span> ||
|}
|}
<!--box uid=421aa90e079fa326b6494f812ad13e79.21183.G46aa3ef21959a-->
<!--box uid=421aa90e079fa326b6494f812ad13e79.21183.G46aa3ef21959a-->
Line 843: Line 843:
*  
*  
****************************************************************************************** -->{{Product_domains_motifs_help}}
****************************************************************************************** -->{{Product_domains_motifs_help}}
{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"   
{|   id="B46aa3ef273d9a" class=" tableEdit Product_motif_table"   
|- {{table heading style}}
|-
!|Type!!Residues!!Description!!Notes
!|Type!!Residues!!Description!!Notes
|-  
|-  
Line 856: Line 856:
[http://www.uniprot.org/uniprot/P50465#section_features UniProt:P50465]  
[http://www.uniprot.org/uniprot/P50465#section_features UniProt:P50465]  


|-class='sortbottom'
|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21183.B46aa3ef273d9a&page=21183&pagename={{FULLPAGENAMEE}}&type=&template=Product_motif_table edit table] || || ||
|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21183.B46aa3ef273d9a&page=21183&pagename={{FULLPAGENAMEE}}&type=&template=Product_motif_table edit table]</span> || || ||
|}
|}
<!--box uid=421aa90e079fa326b6494f812ad13e79.21183.B46aa3ef273d9a--></td>
<!--box uid=421aa90e079fa326b6494f812ad13e79.21183.B46aa3ef273d9a--></td>
Line 877: Line 877:
*  
*  
****************************************************************************************** -->{{Product_structure_help}}
****************************************************************************************** -->{{Product_structure_help}}
{|border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  
{| id="X46aa3ef2be7fb" class=" tableEdit Product_structure_table"


|-
|-
!align=left {{table heading style}} |Structures
!align=left |Structures
||
||
<beststructure>
<beststructure>
Line 887: Line 887:
</beststructure>
</beststructure>
|-
|-
!align=left {{table heading style}} |Models
!align=left |Models
||
||
View models at:
View models at:
Line 896: Line 896:
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)


|-class='sortbottom'
|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21183.X46aa3ef2be7fb&page=21183&pagename={{FULLPAGENAMEE}}&type=1&template=Product_structure_table edit table] ||
|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21183.X46aa3ef2be7fb&page=21183&pagename={{FULLPAGENAMEE}}&type=1&template=Product_structure_table edit table]</span> ||
|}
|}
<!--box uid=421aa90e079fa326b6494f812ad13e79.21183.X46aa3ef2be7fb-->
<!--box uid=421aa90e079fa326b6494f812ad13e79.21183.X46aa3ef2be7fb-->
Line 937: Line 937:
*  
*  
****************************************************************************************** -->{{Product_resources_help}}
****************************************************************************************** -->{{Product_resources_help}}
{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"   
{|   id="J46aa3ef400120" class=" tableEdit Product_resource_table"   
|- {{table_heading_style}}
|-
!|Resource type!!Source!!Notes/Reference
!|Resource type!!Source!!Notes/Reference


|-class='sortbottom'
|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21183.J46aa3ef400120&page=21183&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table] || ||
|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21183.J46aa3ef400120&page=21183&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table]</span> || ||
|}
|}
<!--box uid=421aa90e079fa326b6494f812ad13e79.21183.J46aa3ef400120-->
<!--box uid=421aa90e079fa326b6494f812ad13e79.21183.J46aa3ef400120-->
Line 959: Line 959:
*  
*  
****************************************************************************************** -->{{Gene_accessions_help}}
****************************************************************************************** -->{{Gene_accessions_help}}
{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"   
{|   id="Z46aa3ef44b774" class=" tableEdit Gene_accessions_table"   
|- {{table_heading_style}}
|-
!|Database!!Accession!!Notes
!|Database!!Accession!!Notes
|-  
|-  
Line 991: Line 991:
   
   


|-class='sortbottom'
|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21183.Z46aa3ef44b774&page=21183&pagename={{FULLPAGENAMEE}}&type=0&template=Gene_accessions_table edit table] || ||
|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21183.Z46aa3ef44b774&page=21183&pagename={{FULLPAGENAMEE}}&type=0&template=Gene_accessions_table edit table]</span> || ||
|}
|}
<!--box uid=421aa90e079fa326b6494f812ad13e79.21183.Z46aa3ef44b774-->
<!--box uid=421aa90e079fa326b6494f812ad13e79.21183.Z46aa3ef44b774-->
Line 1,009: Line 1,009:
*  
*  
****************************************************************************************** -->
****************************************************************************************** -->
{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"   
{|   id="X46a7d0a4cb749" class=" tableEdit Links_table"   
|- {{table_heading_style}}
|-
!|Name!!URL!!Comments
!|Name!!URL!!Comments


|-class='sortbottom'
|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21183.X46a7d0a4cb749&page=21183&pagename={{FULLPAGENAMEE}}&type=0&template=Links_table edit table] || ||
|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21183.X46a7d0a4cb749&page=21183&pagename={{FULLPAGENAMEE}}&type=0&template=Links_table edit table]</span> || ||
|}
|}
<!--box uid=421aa90e079fa326b6494f812ad13e79.21183.X46a7d0a4cb749-->
<!--box uid=421aa90e079fa326b6494f812ad13e79.21183.X46a7d0a4cb749-->

Revision as of 02:22, 9 January 2010

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

Nei

Synonyms

endonuclease VIII[1], 5-formyluracil/5-hydroxymethyluracil DNA glycosylase[1], B0714[2][1], Nei[2][1]

Product description

endonuclease VIII[2][3]

DNA glycosylase/apurinic lyase, deoxyinosine-specific; endonuclease VIII[4]

EC number (for enzymes)
edit table


Notes

Function

[back to top]


Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0000703

oxidized pyrimidine base lesion DNA N-glycosylase activity

GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_01253

F

Seeded from EcoCyc [5]

complete

GO:0003676

nucleic acid binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010979

F

Seeded from EcoCyc [5]

complete

GO:0003677

DNA binding

GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR015886
SP_KW:KW-0238

F

Seeded from EcoCyc 12.5 [6]

complete

GO:0003684

damaged DNA binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR012319

F

Seeded from EcoCyc 12.5 [6]

complete

GO:0003824

catalytic activity

GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR015886
SP_KW:KW-0511

F

Seeded from EcoCyc 12.5 [6]

complete

GO:0003906

DNA-(apurinic or apyrimidinic site) lyase activity

GO_REF:0000003
GO_REF:0000020

IEA: Inferred from Electronic Annotation

EC:4.2.99.18
HAMAP:MF_01253

F

Seeded from EcoCyc 12.5 [6]

complete

GO:0006281

DNA repair

GO_REF:0000002
GO_REF:0000004
GO_REF:0000020

IEA: Inferred from Electronic Annotation

InterPro:IPR000214
SP_KW:KW-0234
HAMAP:MF_01253

P

Seeded from EcoCyc 12.5 [6]

complete

GO:0006284

base-excision repair

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR012319

P

Seeded from EcoCyc [5]

complete

GO:0006289

nucleotide-excision repair

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR015886

P

Seeded from EcoCyc [5]

complete

GO:0006974

response to DNA damage stimulus

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0227

P

Seeded from EcoCyc [5]

complete

GO:0008152

metabolic process

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0326

P

Seeded from EcoCyc [5]

complete

GO:0008270

zinc ion binding

GO_REF:0000002
GO_REF:0000002
GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR000214
InterPro:IPR012319
InterPro:IPR015886
SP_KW:KW-0862

F

Seeded from EcoCyc 12.5 [6]

complete

GO:0008534

oxidized purine base lesion DNA N-glycosylase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR012319

F

Seeded from EcoCyc 12.5 [6]

complete

GO:0016787

hydrolase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0378

F

Seeded from EcoCyc [5]

complete

GO:0016798

hydrolase activity, acting on glycosyl bonds

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0326

F

Seeded from EcoCyc [5]

complete

GO:0016829

lyase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0456

F

Seeded from EcoCyc [5]

complete

GO:0046872

metal ion binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0479

F

Seeded from EcoCyc [5]

complete

GO:0005737

cytoplasm

C

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0016799

hydrolase activity, hydrolyzing N-glycosyl compounds

GO_REF:0000002
GO_REF:0000002
GO_REF:0000002
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000214
InterPro:IPR012319
InterPro:IPR015886
InterPro:IPR015887

F

Seeded from EcoCyc [5]

complete

GO:0003906

DNA-(apurinic or apyrimidinic site) lyase activity

PMID:10862773[7]

IDA: Inferred from Direct Assay

F

complete

GO:0008270

zinc ion binding

PMID:16145054[8]

IDA: Inferred from Direct Assay

F

complete

GO:0003684

damaged DNA binding

PMID:17002303[9]

IDA: Inferred from Direct Assay

F

complete

GO:0003684

damaged DNA binding

PMID:10862773[7]

IDA: Inferred from Direct Assay

F

complete

GO:0006284

base-excision repair

PMID:17002303[9]

IDA: Inferred from Direct Assay

P

complete

GO:0003906

DNA-(apurinic or apyrimidinic site) lyase activity

PMID:17002303[9]

IDA: Inferred from Direct Assay

F

complete

edit table

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

hupB

PMID:15690043[10]

Experiment(s):EBI-882379

Protein

lpdA

PMID:15690043[10]

Experiment(s):EBI-882379

Protein

groL

PMID:15690043[10]

Experiment(s):EBI-882379

Protein

rplD

PMID:15690043[10]

Experiment(s):EBI-882379

Protein

rplU

PMID:15690043[10]

Experiment(s):EBI-882379

Protein

rpmB

PMID:15690043[10]

Experiment(s):EBI-882379

Protein

rpsD

PMID:15690043[10]

Experiment(s):EBI-882379

Protein

rpsN

PMID:15690043[10]

Experiment(s):EBI-882379

Protein

slyD

PMID:15690043[10]

Experiment(s):EBI-882379

Protein

nadE

PMID:16606699[11]

Experiment(s):EBI-1137778

Protein

prs

PMID:16606699[11]

Experiment(s):EBI-1137778

Protein

groL

PMID:16606699[11]

Experiment(s):EBI-1137778

DNA

8-oxoG containing substrates

Substrate

PMID:17002303[9]

X-linking

DNA

Tetrahydrofuran analogs

Substrate-processes to a gap

PMID:17002303[9]

Glycosylase assay

DNA

cis-(5S,6R)-thymine glycol (TgA)

Substrate

PMID:17002303[9]

Binding assays

DNA

cis-(5R,6S)-thymine glycol (TgC)

Substrate

PMID:17002303[9]

Binding assays

DNA

5,6-dihydrouracil (DHU)

Substrate

PMID:17002303[9]

Binding assay

edit table


Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Source Notes
edit table


Notes

Structure and Physical Properties

[back to top]


Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence

at EcoCyc 

MPEGPEIRRA ADNLEAAIKG KPLTDVWFAF PQLKPYQSQL IGQHVTHVET RGKALLTHFS
NDLTLYSHNQ LYGVWRVVDT GEEPQTTRVL RVKLQTADKT ILLYSASDIE MLTPEQLTTH
PFLQRVGPDV LDPNLTPEVV KERLLSPRFR NRQFAGLLLD QAFLAGLGNY LRVEILWQVG
LTGNHKAKDL NAAQLDALAH ALLEIPRFSY ATRGQVDENK HHGALFRFKV FHRDGEPCER
CGSIIEKTTL SSRPFYWCPG CQH
Length

263

Mol. Wt

29.845 kDa

pI

8.0 (calculated)

Extinction coefficient

32,430 - 32,930 (calc based on 7 Y, 4 W, and 4 C residues)

edit table


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes

Initiator Methionine

1

Removed

UniProt:P50465

edit table

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=nei taxon=562,83333 </beststructure>

Models

View models at:

edit table

Structure figures

Notes

  • Kinetic properties of Nei are described in [7] and [9]
  • Structures of active and inactive mutants described in [8]
  • Catalytically important residues E2 and R252

Gene Product Resources

[back to top]


See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
edit table


Notes

Accessions in Other Databases

[back to top]


See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:G6383-MONOMER

UniProt (EcoliWiki Page)

UniProt:P50465

PFAM (EcoliWiki Page)

PFAM:PF01149

RefSeq (EcoliWiki Page)

RefSeq:NP_415242


edit table


Notes

Links

[back to top]




References

[back to top]


See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.00 5.01 5.02 5.03 5.04 5.05 5.06 5.07 5.08 5.09 5.10 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
  6. ↑ 6.0 6.1 6.2 6.3 6.4 6.5 6.6 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  7. ↑ 7.0 7.1 7.2 Hazra, TK et al. (2000) Characterization of a novel 8-oxoguanine-DNA glycosylase activity in Escherichia coli and identification of the enzyme as endonuclease VIII. J. Biol. Chem. 275 27762-7 PubMed
  8. ↑ 8.0 8.1 Golan, G et al. (2005) Structure of the uncomplexed DNA repair enzyme endonuclease VIII indicates significant interdomain flexibility. Nucleic Acids Res. 33 5006-16 PubMed
  9. ↑ 9.0 9.1 9.2 9.3 9.4 9.5 9.6 9.7 9.8 Kropachev, KY et al. (2006) Catalytic mechanism of Escherichia coli endonuclease VIII: roles of the intercalation loop and the zinc finger. Biochemistry 45 12039-49 PubMed
  10. ↑ 10.0 10.1 10.2 10.3 10.4 10.5 10.6 10.7 10.8 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
  11. ↑ 11.0 11.1 11.2 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed

Categories

[back to top]


Retrieved from "https://ecoliwiki.org/colipedia/index.php?title=nei:Gene_Product(s)&oldid=983003"