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!align=left {{table_heading_style}} |Standard Name
!align=left |Standard Name
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''ftsK''  
''ftsK''  
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!align=left {{table_heading_style}} |Gene Synonym(s)
!align=left |Gene Synonym(s)
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''ECK0881, b0890, JW0873, dinH''<ref name='LIB:Riley_2006'/>
''ECK0881, b0890, JW0873, dinH''<ref name='LIB:Riley_2006'/>
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!align=left {{table_heading_style}} |Product Desc.
!align=left |Product Desc.
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essential cell division protein FtsK<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
essential cell division protein FtsK<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
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DNA translocase at septal ring sorting daughter chromsomes<ref name='LIB:EcoGene'/>
DNA translocase at septal ring sorting daughter chromsomes<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
!align=left |Product Synonyms(s)
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DNA-binding membrane protein required for chromosome resolution and partitioning<ref name='LIB:Riley_2006'/>, B0890<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DinH<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, FtsK<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
DNA-binding membrane protein required for chromosome resolution and partitioning<ref name='LIB:Riley_2006'/>, B0890<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DinH<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, FtsK<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left {{table_heading_style}} |Knock-Out Phenotype
!align=left |Knock-Out Phenotype
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ts mutants filament
ts mutants filament
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!align=left {{table_heading_style}} |Regulation/Expression
!align=left |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:ftsK|ftsK]]<ref name='LIB:EcoCyc10.6'/>, dinH  
transcription unit(s): [[:Category:Txn_unit:ftsK|ftsK]]<ref name='LIB:EcoCyc10.6'/>, dinH  
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!align=left {{table_heading_style}} |Regulation/Activity
!align=left |Regulation/Activity
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Revision as of 01:14, 9 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

ftsK

Gene Synonym(s)

ECK0881, b0890, JW0873, dinH[1]

Product Desc.

essential cell division protein FtsK[2][3];

Component of Xer site-specific recombination system[3]

DNA translocase at septal ring sorting daughter chromsomes[4]

Product Synonyms(s)

DNA-binding membrane protein required for chromosome resolution and partitioning[1], B0890[2][1], DinH[2][1], FtsK[2][1]

Knock-Out Phenotype

ts mutants filament

Regulation/Expression

transcription unit(s): ftsK[2], dinH

Regulation/Activity


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See Help:Quickview for help with entering information in the Quickview table.

Notes

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FtsK is required for resolution of chromosome dimers at dif by XerCD. FtsK helps keep the nucleoids properly localized, recognizing opposing replichores by using FtsK orienting polar sequences (KOPS). The N-terminal domain is membrane-anchored, localizes to the division septum and is required for cell division. The C-terminal domain has the non-essential translocase activity, which becomes essential for replicating the asymmetric replichores produced by chromosome inversion (Lesterlin, 2008). LexA regulon. Homologous to B. subtilis SpoIIIE protein. The ftsK gene is essential. The filamentous growth of mutants is suppressed by dacA deletions. ftsK44(ts) can be suppressed by an ftsA R286W mutation or by an ftsQAZ plasmid. Divisome.[4]



References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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