cynR:Gene Product(s): Difference between revisions

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!align=left {{table heading style}} |Standard name
!align=left |Standard name
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CynR  
CynR  
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!align=left {{table heading style}} |Synonyms
!align=left |Synonyms
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DNA-binding transcriptional dual regulator<ref name='LIB:Riley_2006'/>, B0338<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, CynR<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, cyn operon positive regulator<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
DNA-binding transcriptional dual regulator<ref name='LIB:Riley_2006'/>, B0338<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, CynR<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, cyn operon positive regulator<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left {{table heading style}} |Product description
!align=left |Product description
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CynR transcriptional dual regulator<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
CynR transcriptional dual regulator<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
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Transcriptional activator of cyn operon<ref name='LIB:EcoGene'/>
Transcriptional activator of cyn operon<ref name='LIB:EcoGene'/>
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!align=left {{table heading style}} |EC number (for enzymes)
!align=left |EC number (for enzymes)
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!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
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complete  
complete  


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!align=left {{table heading style}} |Sequence
!align=left |Sequence
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[http://biocyc.org/ECOLI/sequence-aa?object=PD00291 at EcoCyc]  
[http://biocyc.org/ECOLI/sequence-aa?object=PD00291 at EcoCyc]  
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PAAIATQHDG LKAISLAPPL LERTAVLLRR KNSWQTAAAK AFLHMALDKC AVVGGNESR</pre>  
PAAIATQHDG LKAISLAPPL LERTAVLLRR KNSWQTAAAK AFLHMALDKC AVVGGNESR</pre>  
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!align=left {{table heading style}} |Length
!align=left |Length
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299
299
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!align=left {{table heading style}} |Mol. Wt
!align=left |Mol. Wt
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32.961 kDa
32.961 kDa
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!align=left {{table heading style}} |pI
!align=left |pI
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6.8 (calculated)
6.8 (calculated)
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!align=left {{table heading style}} |Extinction coefficient
!align=left |Extinction coefficient
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19,940 - 20,315 (calc based on 6 Y, 2 W, and 3 C residues)
19,940 - 20,315 (calc based on 6 Y, 2 W, and 3 C residues)


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<beststructure>
<beststructure>
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</beststructure>
</beststructure>
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!align=left {{table heading style}} |Models
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View models at:
View models at:
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* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)


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Revision as of 00:30, 9 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

CynR

Synonyms

DNA-binding transcriptional dual regulator[1], B0338[2][1], CynR[2][1], cyn operon positive regulator[2][1]

Product description

CynR transcriptional dual regulator[2][3]

Transcriptional activator of cyn operon[4]

EC number (for enzymes)


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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0006350

transcription

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0804

P

Seeded from EcoCyc [5]

complete

GO:0006355

regulation of transcription, DNA-dependent

GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR000847
SP_KW:KW-0805

P

Seeded from EcoCyc [5]

complete

GO:0005737

cytoplasm

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0963

C

Seeded from EcoCyc 12.5 [6]

complete

GO:0003700

transcription factor activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000847

F

Seeded from EcoCyc [5]

complete

GO:0003677

DNA binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0238

F

Seeded from EcoCyc [5]

complete

NOT

GO:0006805

xenobiotic metabolic process

P

Seeded from EcoCyc 11.1[3].

required field missing

GO:0016564

transcription repressor activity

PMID:8253686[7]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc 11.1[3].

complete

GO:0016563

transcription activator activity

PMID:1592818[8]

IMP: Inferred from Mutant Phenotype

F

Seeded from EcoCyc 11.1[3].

complete

GO:0016563

transcription activator activity

PMID:8253686[7]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc 11.1[3].

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

DNA

PMID:8253686[7]

Protein

Self

PMID:1592818[8]

PMID:14973045[9]


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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Source Notes
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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence

at EcoCyc 

MLSRHINYFL AVAEHGSFTR AASALHVSQP ALSQQIRQLE ESLGVPLFDR SGRTIRLTDA
GEVWRQYASR ALQELGAGKR AIHDVADLTR GSLRIAVTPT FTSYFIGPLM ADFYARYPSI
TLQLQEMSQE KIEDMLCRDE LDVGIAFAPV HSPELEAIPL LTESLALVVA QHHPLAVHEQ
VALSRLHDEK LVLLSAEFAT REQIDHYCEK AGLHPQVVIE ANSISAVLEL IRRTSLSTLL
PAAIATQHDG LKAISLAPPL LERTAVLLRR KNSWQTAAAK AFLHMALDKC AVVGGNESR
Length

299

Mol. Wt

32.961 kDa

pI

6.8 (calculated)

Extinction coefficient

19,940 - 20,315 (calc based on 6 Y, 2 W, and 3 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes
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<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=cynR taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:PD00291

UniProt (EcoliWiki Page)

UniProt:P27111

RefSeq (EcoliWiki Page)

RefSeq:NP_414872


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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 3.2 3.3 3.4 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 5.2 5.3 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
  6. ↑ EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  7. ↑ 7.0 7.1 7.2 Lamblin, AF & Fuchs, JA (1993) Expression and purification of the cynR regulatory gene product: CynR is a DNA-binding protein. J. Bacteriol. 175 7990-9 PubMed
  8. ↑ 8.0 8.1 Sung, YC & Fuchs, JA (1992) The Escherichia coli K-12 cyn operon is positively regulated by a member of the lysR family. J. Bacteriol. 174 3645-50 PubMed
  9. ↑ Mariño-Ramírez, L et al. (2004) Identification and mapping of self-assembling protein domains encoded by the Escherichia coli K-12 genome by use of lambda repressor fusions. J. Bacteriol. 186 1311-9 PubMed

Categories

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