Genes not mapped to a genome sequence: Difference between revisions
Table edited by Siegele via TableEdit |
Table edited by Siegele via TableEdit |
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|- align='left' bgcolor='#CCCCFF' | |- align='left' bgcolor='#CCCCFF' | ||
!|Gene!!Approx. Map Location!!Mnemonic!!Notes!!Candidate gene(s) | !|Gene!!Approx. Map Location!!Mnemonic!!Paper(s) describine gene!!Notes!!Candidate gene(s) | ||
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| Line 18: | Line 18: | ||
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Arg binding protein | Arg binding protein | ||
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Low-affinity transport system for arginine and ornithine; periplasmic binding protein [[cgsc_site:18562|CGSC]] | Low-affinity transport system for arginine and ornithine; periplasmic binding protein [[cgsc_site:18562|CGSC]] | ||
| Line 29: | Line 31: | ||
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Antibiotic sensitivity | Antibiotic sensitivity | ||
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Sensitivity and permeability to antibiotics and dyes [[cgsc_site:18559|CGSC]] | Sensitivity and permeability to antibiotics and dyes [[cgsc_site:18559|CGSC]] | ||
| Line 40: | Line 44: | ||
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Acyl carrier protein | Acyl carrier protein | ||
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acpS; originally thought to be holo-ACP synthase; perhaps cryptic second gene or regulator [[cgsc_site:1046|CGSC]] | acpS; originally thought to be holo-ACP synthase; perhaps cryptic second gene or regulator [[cgsc_site:1046|CGSC]] | ||
| Line 51: | Line 57: | ||
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Acridine | Acridine | ||
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Sensitivity to acriflavine; transmembrane protein [[cgsc_site:1044|CGSC]] | Sensitivity to acriflavine; transmembrane protein [[cgsc_site:1044|CGSC]] | ||
| Line 62: | Line 70: | ||
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Alcohol dehydrogenase | Alcohol dehydrogenase | ||
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Alcohol dehydrogenase [[cgsc_site:36932|CGSC]] | Alcohol dehydrogenase [[cgsc_site:36932|CGSC]] | ||
| Line 73: | Line 83: | ||
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Acetylgalactosamine | Acetylgalactosamine | ||
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| | | | ||
Cluster of putative N-acetylgalactosamine pathway genes, including the kba gene, and mannose permease homologs [[cgsc_site:55305|CGSC]] | Cluster of putative N-acetylgalactosamine pathway genes, including the kba gene, and mannose permease homologs [[cgsc_site:55305|CGSC]] | ||
| Line 84: | Line 96: | ||
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Aromatic | Aromatic | ||
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Function unknown [[cgsc_site:1000|CGSC]] | Function unknown [[cgsc_site:1000|CGSC]] | ||
| Line 95: | Line 109: | ||
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Azaserine | Azaserine | ||
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Mutants azaserine resistant [[cgsc_site:970|CGSC]] | Mutants azaserine resistant [[cgsc_site:970|CGSC]] | ||
| Line 106: | Line 122: | ||
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Azaserine | Azaserine | ||
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Mutants azaserine resistant [[cgsc_site:969|CGSC]] | Mutants azaserine resistant [[cgsc_site:969|CGSC]] | ||
| Line 117: | Line 135: | ||
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Azaleucine | Azaleucine | ||
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Mutants azaleucine resistant; regulates ilv and leu [[cgsc_site:967|CGSC]] | Mutants azaleucine resistant; regulates ilv and leu [[cgsc_site:967|CGSC]] | ||
| Line 128: | Line 148: | ||
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BF23 multiplication | BF23 multiplication | ||
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Controls phage BF23 multiplication [[cgsc_site:966|CGSC]] | Controls phage BF23 multiplication [[cgsc_site:966|CGSC]] | ||
| Line 139: | Line 161: | ||
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-Glucoside | -Glucoside | ||
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bglE; regulatory gene for BglA [[cgsc_site:961|CGSC]] | bglE; regulatory gene for BglA [[cgsc_site:961|CGSC]] | ||
| Line 150: | Line 174: | ||
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Biotin | Biotin | ||
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| | | | ||
bir, birB; biotin transport [[cgsc_site:953|CGSC]] | bir, birB; biotin transport [[cgsc_site:953|CGSC]] | ||
| Line 162: | Line 188: | ||
Branched chain | Branched chain | ||
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Mutants valine resistant, glycylvaline sensitive | PMID:4590465 | ||
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Mutants valine resistant, glycylvaline sensitive [[cgsc_site:949|CGSC]] | |||
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| Line 173: | Line 201: | ||
Branched chain | Branched chain | ||
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Mutants valine resistant, glycylvaline sensitive | PMID:4590465 | ||
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Mutants valine resistant, glycylvaline sensitive [[cgsc_site:948|CGSC]] | |||
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| Line 183: | Line 213: | ||
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Branched chain | Branched chain | ||
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Low-affinity transport of Ile [[cgsc_site:947|CGSC]] | Low-affinity transport of Ile [[cgsc_site:947|CGSC]] | ||
| Line 194: | Line 226: | ||
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Bypass maltose | Bypass maltose | ||
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Growth on maltose in MalT cells [[cgsc_site:944|CGSC]] | Growth on maltose in MalT cells [[cgsc_site:944|CGSC]] | ||
| Line 205: | Line 239: | ||
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Calcium | Calcium | ||
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Calcium-proton antiport activity [[cgsc_site:941|CGSC]] | Calcium-proton antiport activity [[cgsc_site:941|CGSC]] | ||
| Line 216: | Line 252: | ||
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Calcium | Calcium | ||
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Calcium transport; mutants defective in chemotaxis [[cgsc_site:940|CGSC]] | Calcium transport; mutants defective in chemotaxis [[cgsc_site:940|CGSC]] | ||
| Line 227: | Line 265: | ||
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Calcium | Calcium | ||
| | |||
| | | | ||
Calcium transport; mutants defective in chemotaxis [[cgsc_site:939|CGSC]] | Calcium transport; mutants defective in chemotaxis [[cgsc_site:939|CGSC]] | ||
| Line 238: | Line 278: | ||
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CDP diglyceride synthase | CDP diglyceride synthase | ||
| | |||
| | | | ||
Stability of CDP diglyceride synthase [[cgsc_site:18490|CGSC]] | Stability of CDP diglyceride synthase [[cgsc_site:18490|CGSC]] | ||
| Line 249: | Line 291: | ||
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Capsular polysaccharide synthesis | Capsular polysaccharide synthesis | ||
| | |||
| | | | ||
Colanic acid (CPS) biosynthesis [[cgsc_site:18463|CGSC]] | Colanic acid (CPS) biosynthesis [[cgsc_site:18463|CGSC]] | ||
| Line 260: | Line 304: | ||
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Capsular polysaccharide synthesis | Capsular polysaccharide synthesis | ||
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Colanic acid (CPS) biosynthesis [[cgsc_site:18457|CGSC]] | Colanic acid (CPS) biosynthesis [[cgsc_site:18457|CGSC]] | ||
| Line 271: | Line 317: | ||
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Capsular polysaccharide synthesis | Capsular polysaccharide synthesis | ||
| | |||
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Colanic acid (CPS) biosynthesis [[cgsc_site:18454|CGSC]] | Colanic acid (CPS) biosynthesis [[cgsc_site:18454|CGSC]] | ||
| Line 282: | Line 330: | ||
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Capsular polysaccharide synthesis | Capsular polysaccharide synthesis | ||
| | |||
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Colanic acid (CPS) biosynthesis [[cgsc_site:51241|CGSC]] | Colanic acid (CPS) biosynthesis [[cgsc_site:51241|CGSC]] | ||
| Line 293: | Line 343: | ||
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Capsular polysaccharide synthesis | Capsular polysaccharide synthesis | ||
| | |||
| | | | ||
Colanic acid (CPS) biosynthesis [[cgsc_site:18448|CGSC]] | Colanic acid (CPS) biosynthesis [[cgsc_site:18448|CGSC]] | ||
| Line 304: | Line 356: | ||
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Conjugative plasmid expression | Conjugative plasmid expression | ||
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| | | | ||
Phage Q resistance, membrane protein [[cgsc_site:907|CGSC]] | Phage Q resistance, membrane protein [[cgsc_site:907|CGSC]] | ||
| Line 315: | Line 369: | ||
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Cold resistant growth | Cold resistant growth | ||
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| | | | ||
Allows cold-resistant growth [[cgsc_site:18445|CGSC]] | Allows cold-resistant growth [[cgsc_site:18445|CGSC]] | ||
| Line 326: | Line 382: | ||
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Carbon starvation induced | Carbon starvation induced | ||
| | |||
| | | | ||
Stationary phase inducible protein [[cgsc_site:36892|CGSC]] | Stationary phase inducible protein [[cgsc_site:36892|CGSC]] | ||
| Line 337: | Line 395: | ||
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Carbon starvation induced | Carbon starvation induced | ||
| | |||
| | | | ||
Stationary phase inducible protein [[cgsc_site:36895|CGSC]] | Stationary phase inducible protein [[cgsc_site:36895|CGSC]] | ||
| Line 348: | Line 408: | ||
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Carbon starvation induced | Carbon starvation induced | ||
| | |||
| | | | ||
Stationary phase inducible protein [[cgsc_site:36898|CGSC]] | Stationary phase inducible protein [[cgsc_site:36898|CGSC]] | ||
| Line 359: | Line 421: | ||
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Carbon starvation induced | Carbon starvation induced | ||
| | |||
| | | | ||
Stationary phase inducible protein [[cgsc_site:36998|CGSC]] | Stationary phase inducible protein [[cgsc_site:36998|CGSC]] | ||
| Line 370: | Line 434: | ||
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Carbohydrate uptake | Carbohydrate uptake | ||
| | |||
| | | | ||
Mutants have defective carbohydrate uptake [[cgsc_site:18442|CGSC]] | Mutants have defective carbohydrate uptake [[cgsc_site:18442|CGSC]] | ||
| Line 381: | Line 447: | ||
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Carbon-xylose metabolism | Carbon-xylose metabolism | ||
| | |||
| | | | ||
cxr; methyl glyoxal synthesis; D-xylose utilization [[cgsc_site:903|CGSC]] | cxr; methyl glyoxal synthesis; D-xylose utilization [[cgsc_site:903|CGSC]] | ||
| Line 392: | Line 460: | ||
| | | | ||
Cysteine | Cysteine | ||
| | |||
| | | | ||
Reading frame in opposite orientation within cysE gene; polypeptide synthesized in maxicells [[cgsc_site:55332|CGSC]] | Reading frame in opposite orientation within cysE gene; polypeptide synthesized in maxicells [[cgsc_site:55332|CGSC]] | ||
| Line 403: | Line 473: | ||
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D-Amino acid dehydrogenase | D-Amino acid dehydrogenase | ||
| | |||
| | | | ||
alnR; regulator of dad regulon [[cgsc_site:882|CGSC]] | alnR; regulator of dad regulon [[cgsc_site:882|CGSC]] | ||
| Line 414: | Line 486: | ||
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Dicarboxylic acid transport | Dicarboxylic acid transport | ||
| | |||
| | | | ||
Uptake of C-4 dicarboxylic acids; 3-fluoromalate resistance, D-tartrate resistant [[cgsc_site:871|CGSC]] | Uptake of C-4 dicarboxylic acids; 3-fluoromalate resistance, D-tartrate resistant [[cgsc_site:871|CGSC]] | ||
| Line 425: | Line 499: | ||
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Deletion | Deletion | ||
| | |||
| | | | ||
Affects frequency of IS1-mediated deletions; 1,000-fold reduction in deletion frequency [[cgsc_site:869|CGSC]] | Affects frequency of IS1-mediated deletions; 1,000-fold reduction in deletion frequency [[cgsc_site:869|CGSC]] | ||
| Line 436: | Line 512: | ||
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Diglyceride kinase | Diglyceride kinase | ||
| | |||
| | | | ||
Regulatory [[cgsc_site:861|CGSC]] | Regulatory [[cgsc_site:861|CGSC]] | ||
| Line 447: | Line 525: | ||
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Damage inducible | Damage inducible | ||
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| | | | ||
Repair gene [[cgsc_site:36880|CGSC]] | Repair gene [[cgsc_site:36880|CGSC]] | ||
| Line 458: | Line 538: | ||
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DNA | DNA | ||
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| | | | ||
DNA biosynthesis [[cgsc_site:846|CGSC]] | DNA biosynthesis [[cgsc_site:846|CGSC]] | ||
| Line 469: | Line 551: | ||
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Dipeptide permease | Dipeptide permease | ||
| | |||
| | | | ||
Uptake of dipeptides; dipeptide permease [[cgsc_site:835|CGSC]] | Uptake of dipeptides; dipeptide permease [[cgsc_site:835|CGSC]] | ||
| Line 480: | Line 564: | ||
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Dye-visible light? | Dye-visible light? | ||
| | |||
| | | | ||
Sensitivity to SDS and toluidine blue plus light [[cgsc_site:18418|CGSC]] | Sensitivity to SDS and toluidine blue plus light [[cgsc_site:18418|CGSC]] | ||
| Line 491: | Line 577: | ||
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Evolved -galactosidase | Evolved -galactosidase | ||
| | |||
| | | | ||
Cryptic -galactoside utilization, possible paralog of lacY [[cgsc_site:18415|CGSC]] | Cryptic -galactoside utilization, possible paralog of lacY [[cgsc_site:18415|CGSC]] | ||
| Line 502: | Line 590: | ||
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Envelope | Envelope | ||
| | |||
| | | | ||
Affects envelope; defects osmotically remedied [[cgsc_site:811|CGSC]] | Affects envelope; defects osmotically remedied [[cgsc_site:811|CGSC]] | ||
| Line 513: | Line 603: | ||
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Envelope | Envelope | ||
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Affects envelope; defects osmotically remedied [[cgsc_site:810|CGSC]] | Affects envelope; defects osmotically remedied [[cgsc_site:810|CGSC]] | ||
| Line 524: | Line 616: | ||
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Envelope | Envelope | ||
| | |||
| | | | ||
Affects envelope; defects osmotically remedied [[cgsc_site:809|CGSC]] | Affects envelope; defects osmotically remedied [[cgsc_site:809|CGSC]] | ||
| Line 535: | Line 629: | ||
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Envelope | Envelope | ||
| | |||
| | | | ||
Affects envelope; defects osmotically remedied [[cgsc_site:808|CGSC]] | Affects envelope; defects osmotically remedied [[cgsc_site:808|CGSC]] | ||
| Line 546: | Line 642: | ||
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E-pentapeptide | E-pentapeptide | ||
| | |||
| | | | ||
Minigene within 23S rRNA encoding functional pentapeptide; erythromycin resistance [[cgsc_site:51135|CGSC]] | Minigene within 23S rRNA encoding functional pentapeptide; erythromycin resistance [[cgsc_site:51135|CGSC]] | ||
| Line 557: | Line 655: | ||
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Efficiency site for phage | Efficiency site for phage | ||
| | |||
| | | | ||
Site for efficient packaging of phage T1 [[cgsc_site:805|CGSC]] | Site for efficient packaging of phage T1 [[cgsc_site:805|CGSC]] | ||
| Line 568: | Line 668: | ||
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Export | Export | ||
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Uptake of enterochelin; resistance or sensitivity to colicins [[cgsc_site:803|CGSC]] | Uptake of enterochelin; resistance or sensitivity to colicins [[cgsc_site:803|CGSC]] | ||
| Line 579: | Line 681: | ||
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Export | Export | ||
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Expression of a group of export proteins [[cgsc_site:802|CGSC]] | Expression of a group of export proteins [[cgsc_site:802|CGSC]] | ||
| Line 590: | Line 694: | ||
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Fatty acid | Fatty acid | ||
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| | | | ||
Utilization of trans unsaturated fatty acids [[cgsc_site:18403|CGSC]] | Utilization of trans unsaturated fatty acids [[cgsc_site:18403|CGSC]] | ||
| Line 601: | Line 707: | ||
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Filamentous, cold sensitive | Filamentous, cold sensitive | ||
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Cold-sensitive cell division mutant [[cgsc_site:787|CGSC]] | Cold-sensitive cell division mutant [[cgsc_site:787|CGSC]] | ||
| Line 612: | Line 720: | ||
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F exclusion | F exclusion | ||
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Affects ArcA phenotype [[cgsc_site:778|CGSC]] | Affects ArcA phenotype [[cgsc_site:778|CGSC]] | ||
| Line 623: | Line 733: | ||
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Formate hydrogen-lyase | Formate hydrogen-lyase | ||
| | |||
| | | | ||
Formate hydrogen-lyase; activated by fhlA [[cgsc_site:36851|CGSC]] | Formate hydrogen-lyase; activated by fhlA [[cgsc_site:36851|CGSC]] | ||
| Line 634: | Line 746: | ||
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F1 phage | F1 phage | ||
| | |||
| | | | ||
Morphogenesis of phage F1 [[cgsc_site:18334|CGSC]] | Morphogenesis of phage F1 [[cgsc_site:18334|CGSC]] | ||
| Line 645: | Line 759: | ||
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F1 phage | F1 phage | ||
| | |||
| | | | ||
Morphogenesis of phage F1 [[cgsc_site:18331|CGSC]] | Morphogenesis of phage F1 [[cgsc_site:18331|CGSC]] | ||
| Line 656: | Line 772: | ||
| | | | ||
FKBP-like | FKBP-like | ||
| | |||
| | | | ||
Periplasmic PPIase, of FK506-binding protein type (EC 5.2.1.8); contains pipecolic acid residue [[cgsc_site:48137|CGSC]] | Periplasmic PPIase, of FK506-binding protein type (EC 5.2.1.8); contains pipecolic acid residue [[cgsc_site:48137|CGSC]] | ||
| Line 667: | Line 785: | ||
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Glutamate deCase | Glutamate deCase | ||
| | |||
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Regulatory gene for gat? [[cgsc_site:726|CGSC]] | Regulatory gene for gat? [[cgsc_site:726|CGSC]] | ||
| Line 678: | Line 798: | ||
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Glucarate | Glucarate | ||
| | |||
| | | | ||
D-Glucarate utilization [[cgsc_site:717|CGSC]] | D-Glucarate utilization [[cgsc_site:717|CGSC]] | ||
| Line 689: | Line 811: | ||
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Glucarate | Glucarate | ||
| | |||
| | | | ||
D-Glucarate utilization [[cgsc_site:716|CGSC]] | D-Glucarate utilization [[cgsc_site:716|CGSC]] | ||
| Line 700: | Line 824: | ||
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Glucosamine | Glucosamine | ||
| | |||
| | | | ||
Affects suppression of glmS mutations by nagB [[cgsc_site:36538|CGSC]] | Affects suppression of glmS mutations by nagB [[cgsc_site:36538|CGSC]] | ||
| Line 711: | Line 837: | ||
| | | | ||
Glutamate | Glutamate | ||
| | |||
| | | | ||
Glutamyl-tRNA synthetase; possible regulatory subunit [[cgsc_site:685|CGSC]] | Glutamyl-tRNA synthetase; possible regulatory subunit [[cgsc_site:685|CGSC]] | ||
| Line 722: | Line 850: | ||
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Glutamate | Glutamate | ||
| | |||
| | | | ||
Growth on glutamate [[cgsc_site:684|CGSC]] | Growth on glutamate [[cgsc_site:684|CGSC]] | ||
| Line 733: | Line 863: | ||
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Glutamate | Glutamate | ||
| | |||
| | | | ||
Growth on glutamate at 42C [[cgsc_site:682|CGSC]] | Growth on glutamate at 42C [[cgsc_site:682|CGSC]] | ||
| Line 744: | Line 876: | ||
| | | | ||
Growth of phage, replication | Growth of phage, replication | ||
| | |||
| | | | ||
Replication of certain lambdoid phage [[cgsc_site:15896|CGSC]] | Replication of certain lambdoid phage [[cgsc_site:15896|CGSC]] | ||
| Line 755: | Line 889: | ||
| | | | ||
Growth of phage, replication | Growth of phage, replication | ||
| | |||
| | | | ||
Replication of certain lambdoid phage [[cgsc_site:15890|CGSC]] | Replication of certain lambdoid phage [[cgsc_site:15890|CGSC]] | ||
| Line 766: | Line 902: | ||
| | | | ||
Glucuronide | Glucuronide | ||
| | |||
| | | | ||
Utilization of glucuronides [[cgsc_site:653|CGSC]] | Utilization of glucuronides [[cgsc_site:653|CGSC]] | ||
| Line 777: | Line 915: | ||
| | | | ||
Heterogeneous size | Heterogeneous size | ||
| | |||
| | | | ||
cop; possibly structural gene for DNA-binding protein; near ori [[cgsc_site:640|CGSC]] | cop; possibly structural gene for DNA-binding protein; near ori [[cgsc_site:640|CGSC]] | ||
| Line 788: | Line 928: | ||
| | | | ||
Heat shock locus | Heat shock locus | ||
| | |||
| | | | ||
Protein expressed as heat shock regulon member [[cgsc_site:36762|CGSC]] | Protein expressed as heat shock regulon member [[cgsc_site:36762|CGSC]] | ||
| Line 799: | Line 941: | ||
| | | | ||
Heat shock locus | Heat shock locus | ||
| | |||
| | | | ||
Protein expressed as heat shock regulon member [[cgsc_site:36765|CGSC]] | Protein expressed as heat shock regulon member [[cgsc_site:36765|CGSC]] | ||
| Line 810: | Line 954: | ||
| | | | ||
Heat shock locus | Heat shock locus | ||
| | |||
| | | | ||
Protein expressed as heat shock regulon member [[cgsc_site:36945|CGSC]] | Protein expressed as heat shock regulon member [[cgsc_site:36945|CGSC]] | ||
| Line 821: | Line 967: | ||
| | | | ||
Heat shock locus | Heat shock locus | ||
| | |||
| | | | ||
Heat-inducible; regulatory gene, near groE [[cgsc_site:41190|CGSC]] | Heat-inducible; regulatory gene, near groE [[cgsc_site:41190|CGSC]] | ||
| Line 832: | Line 980: | ||
| | | | ||
Isoleucine-valine (requirement) | Isoleucine-valine (requirement) | ||
| | |||
| | | | ||
Production of valine-resistant acetolactate synthase activity [[cgsc_site:604|CGSC]] | Production of valine-resistant acetolactate synthase activity [[cgsc_site:604|CGSC]] | ||
| Line 843: | Line 993: | ||
| | | | ||
Isoleucine-valine | Isoleucine-valine | ||
| | |||
| | | | ||
[[cgsc_site:15917|CGSC]] | [[cgsc_site:15917|CGSC]] | ||
| Line 854: | Line 1,006: | ||
| | | | ||
Isoleucine-valine (requirement) | Isoleucine-valine (requirement) | ||
| | |||
| | | | ||
Regulation of ileS and modification of Ile tRNA2 and Val tRNA2 [[cgsc_site:599|CGSC]] | Regulation of ileS and modification of Ile tRNA2 and Val tRNA2 [[cgsc_site:599|CGSC]] | ||
| Line 865: | Line 1,019: | ||
| | | | ||
Insensitive NG mutagenesis | Insensitive NG mutagenesis | ||
| | |||
| | | | ||
Susceptibility to mutagenesis by nitrosoguanidine [[cgsc_site:595|CGSC]] | Susceptibility to mutagenesis by nitrosoguanidine [[cgsc_site:595|CGSC]] | ||
| Line 876: | Line 1,032: | ||
| | | | ||
Inhibits SOS function | Inhibits SOS function | ||
| | |||
| | | | ||
Regulatory gene; SOS-related [[cgsc_site:41044|CGSC]] | Regulatory gene; SOS-related [[cgsc_site:41044|CGSC]] | ||
| Line 887: | Line 1,045: | ||
| | | | ||
Kasugamycin | Kasugamycin | ||
| | |||
| | | | ||
High-level resistance to kasugamycin [[cgsc_site:582|CGSC]] | High-level resistance to kasugamycin [[cgsc_site:582|CGSC]] | ||
| Line 898: | Line 1,058: | ||
| | | | ||
Kasugamycin | Kasugamycin | ||
| | |||
| | | | ||
Resistance to kasugamycin; affects ribosomal protein S2 [[cgsc_site:581|CGSC]] | Resistance to kasugamycin; affects ribosomal protein S2 [[cgsc_site:581|CGSC]] | ||
| Line 909: | Line 1,071: | ||
| | | | ||
Kasugamycin | Kasugamycin | ||
| | |||
| | | | ||
Resistance to kasugamycin [[cgsc_site:580|CGSC]] | Resistance to kasugamycin [[cgsc_site:580|CGSC]] | ||
| Line 920: | Line 1,084: | ||
| | | | ||
Leucine (biosynthesis) | Leucine (biosynthesis) | ||
| | |||
| | | | ||
flr; regulation of leu and ilv operons [[cgsc_site:18196|CGSC]] | flr; regulation of leu and ilv operons [[cgsc_site:18196|CGSC]] | ||
| Line 931: | Line 1,097: | ||
| | | | ||
Leucine | Leucine | ||
| | |||
| | | | ||
Regulates level of leucyl-tRNA synthetase [[cgsc_site:567|CGSC]] | Regulates level of leucyl-tRNA synthetase [[cgsc_site:567|CGSC]] | ||
| Line 942: | Line 1,110: | ||
| | | | ||
Leucine | Leucine | ||
| | |||
| | | | ||
Regulates level of leucyl-tRNA synthetase [[cgsc_site:560|CGSC]] | Regulates level of leucyl-tRNA synthetase [[cgsc_site:560|CGSC]] | ||
| Line 953: | Line 1,123: | ||
| | | | ||
Levallorphan | Levallorphan | ||
| | |||
| | | | ||
Resistance to levallorphan [[cgsc_site:559|CGSC]] | Resistance to levallorphan [[cgsc_site:559|CGSC]] | ||
| Line 964: | Line 1,136: | ||
| | | | ||
Lincomycin | Lincomycin | ||
| | |||
| | | | ||
High-level lincomycin resistance [[cgsc_site:556|CGSC]] | High-level lincomycin resistance [[cgsc_site:556|CGSC]] | ||
| Line 975: | Line 1,149: | ||
| | | | ||
Lipopolysaccharide core | Lipopolysaccharide core | ||
| | |||
| | | | ||
mrc, pon; T-phage resistance, novobiocin sensitivity [[cgsc_site:545|CGSC]] | mrc, pon; T-phage resistance, novobiocin sensitivity [[cgsc_site:545|CGSC]] | ||
| Line 986: | Line 1,162: | ||
| | | | ||
L-Ribose (utilization) | L-Ribose (utilization) | ||
| | |||
| | | | ||
Affects NADPH-linked L-ribose reductase activity [[cgsc_site:36791|CGSC]] | Affects NADPH-linked L-ribose reductase activity [[cgsc_site:36791|CGSC]] | ||
| Line 997: | Line 1,175: | ||
| | | | ||
Lysine | Lysine | ||
| | |||
| | | | ||
Lysine excretion [[cgsc_site:536|CGSC]] | Lysine excretion [[cgsc_site:536|CGSC]] | ||
| Line 1,008: | Line 1,188: | ||
| | | | ||
Lytic | Lytic | ||
| | |||
| | | | ||
Tolerance to -lactams; autolysis [[cgsc_site:18184|CGSC]] | Tolerance to -lactams; autolysis [[cgsc_site:18184|CGSC]] | ||
| Line 1,019: | Line 1,201: | ||
| | | | ||
Maintenance of F | Maintenance of F | ||
| | |||
PMID:327277 | |||
PMID:391803 | |||
| | | | ||
Maintenance of F-like plasmids [[cgsc_site:534|CGSC]] | Maintenance of F-like plasmids [[cgsc_site:534|CGSC]] | ||
| Line 1,030: | Line 1,215: | ||
| | | | ||
Maintenance of F | Maintenance of F | ||
| | |||
PMID:391803 | |||
| | | | ||
Maintenance of F-like plasmids [[cgsc_site:533|CGSC]] | Maintenance of F-like plasmids [[cgsc_site:533|CGSC]] | ||
| Line 1,041: | Line 1,228: | ||
| | | | ||
Mothball resistant | Mothball resistant | ||
| | |||
| | | | ||
Resistance to camphor vapors; coupling of cell division and replication, growth rate and partitioning [[cgsc_site:36929|CGSC]] | Resistance to camphor vapors; coupling of cell division and replication, growth rate and partitioning [[cgsc_site:36929|CGSC]] | ||
| Line 1,052: | Line 1,241: | ||
| | | | ||
malE bypass | malE bypass | ||
| | |||
| | | | ||
Suppressor of malE secB-defective transport of mal-binding protein [[cgsc_site:28194|CGSC]] | Suppressor of malE secB-defective transport of mal-binding protein [[cgsc_site:28194|CGSC]] | ||
| Line 1,063: | Line 1,254: | ||
| | | | ||
Methyl-galactoside | Methyl-galactoside | ||
| | |||
| | | | ||
R-MG; regulatory gene [[cgsc_site:498|CGSC]] | R-MG; regulatory gene [[cgsc_site:498|CGSC]] | ||
| Line 1,074: | Line 1,267: | ||
| | | | ||
Manganese | Manganese | ||
| | |||
| | | | ||
Manganese resistance [[cgsc_site:494|CGSC]] | Manganese resistance [[cgsc_site:494|CGSC]] | ||
| Line 1,085: | Line 1,280: | ||
| | | | ||
Murein cluster a | Murein cluster a | ||
| | |||
| | | | ||
D-Alanine carboxypeptidase [[cgsc_site:489|CGSC]] | D-Alanine carboxypeptidase [[cgsc_site:489|CGSC]] | ||
| Line 1,096: | Line 1,293: | ||
| | | | ||
Mutability lambda | Mutability lambda | ||
| | |||
| | | | ||
Mutability in UV-radiated lambda phage [[cgsc_site:477|CGSC]] | Mutability in UV-radiated lambda phage [[cgsc_site:477|CGSC]] | ||
| Line 1,107: | Line 1,306: | ||
| | | | ||
Murein | Murein | ||
| | |||
| | | | ||
Terminal stage in peptidoglycan synthesis, incorporating disaccharide peptide units into wall [[cgsc_site:18136|CGSC]] | Terminal stage in peptidoglycan synthesis, incorporating disaccharide peptide units into wall [[cgsc_site:18136|CGSC]] | ||
| Line 1,118: | Line 1,319: | ||
| | | | ||
Mutator | Mutator | ||
| | |||
| | | | ||
Mutation causes high C-to-T mutation in second C of CCAGG; near but distinct from vsr; provisionally termed mutG [[cgsc_site:28933|CGSC]] | Mutation causes high C-to-T mutation in second C of CCAGG; near but distinct from vsr; provisionally termed mutG [[cgsc_site:28933|CGSC]] | ||
| Line 1,129: | Line 1,332: | ||
| | | | ||
Nalidixic acid | Nalidixic acid | ||
| | |||
| | | | ||
Sensitivity to nalidixic acid (NAL) [[cgsc_site:460|CGSC]] | Sensitivity to nalidixic acid (NAL) [[cgsc_site:460|CGSC]] | ||
| Line 1,140: | Line 1,345: | ||
| | | | ||
Neamine | Neamine | ||
| | |||
| | | | ||
Neamine sensitivity [[cgsc_site:456|CGSC]] | Neamine sensitivity [[cgsc_site:456|CGSC]] | ||
| Line 1,151: | Line 1,358: | ||
| | | | ||
Nitrofurantoin | Nitrofurantoin | ||
| | |||
| | | | ||
Nitrofurantoin sensitivity [[cgsc_site:18100|CGSC]] | Nitrofurantoin sensitivity [[cgsc_site:18100|CGSC]] | ||
| Line 1,162: | Line 1,371: | ||
| | | | ||
N4 (phage) resistant | N4 (phage) resistant | ||
| | |||
| | | | ||
Phage N4 susceptibility [[cgsc_site:36113|CGSC]] | Phage N4 susceptibility [[cgsc_site:36113|CGSC]] | ||
| Line 1,173: | Line 1,384: | ||
| | | | ||
Nonmucoid | Nonmucoid | ||
| | |||
| | | | ||
Affects capsule formation [[cgsc_site:446|CGSC]] | Affects capsule formation [[cgsc_site:446|CGSC]] | ||
| Line 1,184: | Line 1,397: | ||
| | | | ||
Oligopeptide permease | Oligopeptide permease | ||
| | |||
| | | | ||
Oligopeptide transport [[cgsc_site:18082|CGSC]] | Oligopeptide transport [[cgsc_site:18082|CGSC]] | ||
| Line 1,195: | Line 1,410: | ||
| | | | ||
rpo reversed | rpo reversed | ||
| | |||
| | | | ||
Rate of degradation of aberrant RNAP-subunit proteins [[cgsc_site:18079|CGSC]] | Rate of degradation of aberrant RNAP-subunit proteins [[cgsc_site:18079|CGSC]] | ||
| Line 1,206: | Line 1,423: | ||
| | | | ||
Overproduction of polysaccharide | Overproduction of polysaccharide | ||
| | |||
| | | | ||
Level of exopolysaccharide production [[cgsc_site:18076|CGSC]] | Level of exopolysaccharide production [[cgsc_site:18076|CGSC]] | ||
| Line 1,217: | Line 1,436: | ||
| | | | ||
Origin of replication | Origin of replication | ||
| | |||
| | | | ||
Locus in defective prophage rac [[cgsc_site:430|CGSC]] | Locus in defective prophage rac [[cgsc_site:430|CGSC]] | ||
| Line 1,228: | Line 1,449: | ||
| | | | ||
Phenylacetate | Phenylacetate | ||
| | |||
| | | | ||
Phenylacetate degradation [[cgsc_site:18067|CGSC]] | Phenylacetate degradation [[cgsc_site:18067|CGSC]] | ||
| Line 1,239: | Line 1,462: | ||
| | | | ||
Phage X | Phage X | ||
| | |||
| | | | ||
Adsorption of X154 [[cgsc_site:389|CGSC]] | Adsorption of X154 [[cgsc_site:389|CGSC]] | ||
| Line 1,250: | Line 1,475: | ||
| | | | ||
Proline oxidase | Proline oxidase | ||
| | |||
| | | | ||
Regulation of proline oxidase production [[cgsc_site:377|CGSC]] | Regulation of proline oxidase production [[cgsc_site:377|CGSC]] | ||
| Line 1,261: | Line 1,488: | ||
| | | | ||
Porphyrin | Porphyrin | ||
| | |||
| | | | ||
5-Aminolevulinate dehydratase (EC 4.2.1.24) [[cgsc_site:371|CGSC]] | 5-Aminolevulinate dehydratase (EC 4.2.1.24) [[cgsc_site:371|CGSC]] | ||
| Line 1,272: | Line 1,501: | ||
| | | | ||
Protein localization | Protein localization | ||
| | |||
| | | | ||
Suppresses export defects in signal sequence mutations [[cgsc_site:36421|CGSC]] | Suppresses export defects in signal sequence mutations [[cgsc_site:36421|CGSC]] | ||
| Line 1,283: | Line 1,514: | ||
| | | | ||
Proline | Proline | ||
| | |||
| | | | ||
Proline transport carrier protein, putative [[cgsc_site:359|CGSC]] | Proline transport carrier protein, putative [[cgsc_site:359|CGSC]] | ||
| Line 1,294: | Line 1,527: | ||
| | | | ||
Reverse of sup (amber) | Reverse of sup (amber) | ||
| | |||
| | | | ||
Reverses accentuation effects of amber suppressor on relB mutations [[cgsc_site:334|CGSC]] | Reverses accentuation effects of amber suppressor on relB mutations [[cgsc_site:334|CGSC]] | ||
| Line 1,305: | Line 1,540: | ||
| | | | ||
Q independent | Q independent | ||
| | |||
| | | | ||
kim; cryptic lambdoid phage [[cgsc_site:17529|CGSC]] | kim; cryptic lambdoid phage [[cgsc_site:17529|CGSC]] | ||
| Line 1,316: | Line 1,553: | ||
| | | | ||
Q membrane | Q membrane | ||
| | |||
| | | | ||
Glycine resistance; penicillin sensitivity; membrane defect [[cgsc_site:321|CGSC]] | Glycine resistance; penicillin sensitivity; membrane defect [[cgsc_site:321|CGSC]] | ||
| Line 1,327: | Line 1,566: | ||
| | | | ||
Q membrane | Q membrane | ||
| | |||
| | | | ||
Glycine resistance; penicillin sensitivity; membrane defect [[cgsc_site:320|CGSC]] | Glycine resistance; penicillin sensitivity; membrane defect [[cgsc_site:320|CGSC]] | ||
| Line 1,338: | Line 1,579: | ||
| | | | ||
Q membrane | Q membrane | ||
| | |||
| | | | ||
Glycine resistance; penicillin sensitivity; membrane defect [[cgsc_site:319|CGSC]] | Glycine resistance; penicillin sensitivity; membrane defect [[cgsc_site:319|CGSC]] | ||
| Line 1,349: | Line 1,592: | ||
| | | | ||
Radiation sensitive | Radiation sensitive | ||
| | |||
| | | | ||
Sensitive to X rays and UV [[cgsc_site:316|CGSC]] | Sensitive to X rays and UV [[cgsc_site:316|CGSC]] | ||
| Line 1,360: | Line 1,605: | ||
| | | | ||
RecA-dependent growth | RecA-dependent growth | ||
| | |||
| | | | ||
Dependence of growth upon recA gene product [[cgsc_site:17971|CGSC]] | Dependence of growth upon recA gene product [[cgsc_site:17971|CGSC]] | ||
| Line 1,371: | Line 1,618: | ||
| | | | ||
Relaxed | Relaxed | ||
| | |||
| | | | ||
Control of ppGpp synthesis [[cgsc_site:304|CGSC]] | Control of ppGpp synthesis [[cgsc_site:304|CGSC]] | ||
| Line 1,382: | Line 1,631: | ||
| | | | ||
Resistance to radiation | Resistance to radiation | ||
| | |||
| | | | ||
Resistance to UV and gamma radiation [[cgsc_site:302|CGSC]] | Resistance to UV and gamma radiation [[cgsc_site:302|CGSC]] | ||
| Line 1,393: | Line 1,644: | ||
| | | | ||
Rifampin dependence | Rifampin dependence | ||
| | |||
| | | | ||
Rifampin resistance and dependence [[cgsc_site:285|CGSC]] | Rifampin resistance and dependence [[cgsc_site:285|CGSC]] | ||
| Line 1,404: | Line 1,657: | ||
| | | | ||
Rifampin dependence | Rifampin dependence | ||
| | |||
| | | | ||
Transcription and translation; rifampin (rifamycin) sensitivity [[cgsc_site:17935|CGSC]] | Transcription and translation; rifampin (rifamycin) sensitivity [[cgsc_site:17935|CGSC]] | ||
| Line 1,415: | Line 1,670: | ||
| | | | ||
Ribosomal modification | Ribosomal modification | ||
| | |||
| | | | ||
50S ribosomal subunit maturation [[cgsc_site:284|CGSC]] | 50S ribosomal subunit maturation [[cgsc_site:284|CGSC]] | ||
| Line 1,426: | Line 1,683: | ||
| | | | ||
Ribosomal modification | Ribosomal modification | ||
| | |||
| | | | ||
50S ribosomal subunit maturation [[cgsc_site:283|CGSC]] | 50S ribosomal subunit maturation [[cgsc_site:283|CGSC]] | ||
| Line 1,437: | Line 1,696: | ||
| | | | ||
Ribosomal modification | Ribosomal modification | ||
| | |||
| | | | ||
50S ribosomal subunit maturation [[cgsc_site:282|CGSC]] | 50S ribosomal subunit maturation [[cgsc_site:282|CGSC]] | ||
| Line 1,448: | Line 1,709: | ||
| | | | ||
Ribosomal modification | Ribosomal modification | ||
| | |||
| | | | ||
Ribosomal protein modification [[cgsc_site:281|CGSC]] | Ribosomal protein modification [[cgsc_site:281|CGSC]] | ||
| Line 1,459: | Line 1,722: | ||
| | | | ||
Ribosomal modification | Ribosomal modification | ||
| | |||
| | | | ||
stsB; ribosomal modification [[cgsc_site:278|CGSC]] | stsB; ribosomal modification [[cgsc_site:278|CGSC]] | ||
| Line 1,470: | Line 1,735: | ||
| | | | ||
Ribosomal thermolability | Ribosomal thermolability | ||
| | |||
| | | | ||
Affects thermolability of 50S ribosomal subunit [[cgsc_site:274|CGSC]] | Affects thermolability of 50S ribosomal subunit [[cgsc_site:274|CGSC]] | ||
| Line 1,481: | Line 1,748: | ||
| | | | ||
Roentgen resistance | Roentgen resistance | ||
| | |||
| | | | ||
Sensitivity to ionizing radiation, mitomycin C [[cgsc_site:36611|CGSC]] | Sensitivity to ionizing radiation, mitomycin C [[cgsc_site:36611|CGSC]] | ||
| Line 1,492: | Line 1,761: | ||
| | | | ||
Suppresses disulfide bond | Suppresses disulfide bond | ||
| | |||
| | | | ||
Motility defects [[cgsc_site:|CGSC]] | Motility defects [[cgsc_site:|CGSC]] | ||
| Line 1,503: | Line 1,774: | ||
| | | | ||
Sensitivity to microcin | Sensitivity to microcin | ||
| | |||
| | | | ||
Sensitivity to microcin E492 [[cgsc_site:17884|CGSC]] | Sensitivity to microcin E492 [[cgsc_site:17884|CGSC]] | ||
| Line 1,514: | Line 1,787: | ||
| | | | ||
Serine | Serine | ||
| | |||
| | | | ||
Regulates level of seryl-tRNA synthetase [[cgsc_site:|CGSC]] | Regulates level of seryl-tRNA synthetase [[cgsc_site:|CGSC]] | ||
| Line 1,525: | Line 1,800: | ||
| | | | ||
Septum formation inhibition | Septum formation inhibition | ||
| | |||
| | | | ||
Element of e14, inhibitor of cell division [[cgsc_site:17875|CGSC]] | Element of e14, inhibitor of cell division [[cgsc_site:17875|CGSC]] | ||
| Line 1,536: | Line 1,813: | ||
| | | | ||
Suppressor of increased permeability | Suppressor of increased permeability | ||
| | |||
| | | | ||
Mutations reverse the susceptibility to vancomycin and other hydrophobic antibiotics caused by TraT plasmid gene [[cgsc_site:51306|CGSC]] | Mutations reverse the susceptibility to vancomycin and other hydrophobic antibiotics caused by TraT plasmid gene [[cgsc_site:51306|CGSC]] | ||
| Line 1,547: | Line 1,826: | ||
| | | | ||
Suppressor of increased permeability | Suppressor of increased permeability | ||
| | |||
| | | | ||
Same phenotype as that produced by sipC [[cgsc_site:36869|CGSC]] | Same phenotype as that produced by sipC [[cgsc_site:36869|CGSC]] | ||
| Line 1,558: | Line 1,839: | ||
| | | | ||
SOS-independent repair | SOS-independent repair | ||
| | |||
| | | | ||
SOS-independent repair of mitomycin C-induced DNA damage [[cgsc_site:36505|CGSC]] | SOS-independent repair of mitomycin C-induced DNA damage [[cgsc_site:36505|CGSC]] | ||
| Line 1,569: | Line 1,852: | ||
| | | | ||
Slow growth | Slow growth | ||
| | |||
| | | | ||
Tolerance for amidinopenicillin and nalidixic acid; slow growth rate [[cgsc_site:162|CGSC]] | Tolerance for amidinopenicillin and nalidixic acid; slow growth rate [[cgsc_site:162|CGSC]] | ||
| Line 1,580: | Line 1,865: | ||
| | | | ||
Sorbitol | Sorbitol | ||
| | |||
| | | | ||
gutR; regulatory gene for srl [[cgsc_site:152|CGSC]] | gutR; regulatory gene for srl [[cgsc_site:152|CGSC]] | ||
| Line 1,591: | Line 1,878: | ||
| | | | ||
Stable RNA | Stable RNA | ||
| | |||
| | | | ||
Degradation of stable RNA [[cgsc_site:151|CGSC]] | Degradation of stable RNA [[cgsc_site:151|CGSC]] | ||
| Line 1,602: | Line 1,891: | ||
| | | | ||
Suppression secA | Suppression secA | ||
| | |||
| | | | ||
Suppresses secA mutations [[cgsc_site:17869|CGSC]] | Suppresses secA mutations [[cgsc_site:17869|CGSC]] | ||
| Line 1,613: | Line 1,904: | ||
| | | | ||
Suppression secA | Suppression secA | ||
| | |||
| | | | ||
Suppresses secA mutations [[cgsc_site:17866|CGSC]] | Suppresses secA mutations [[cgsc_site:17866|CGSC]] | ||
| Line 1,624: | Line 1,917: | ||
| | | | ||
Suppression secA | Suppression secA | ||
| | |||
| | | | ||
Suppresses secA mutations [[cgsc_site:17863|CGSC]] | Suppresses secA mutations [[cgsc_site:17863|CGSC]] | ||
| Line 1,635: | Line 1,930: | ||
| | | | ||
Suppression of secY | Suppression of secY | ||
| | |||
| | | | ||
Suppressor of secY mutation [[cgsc_site:17848|CGSC]] | Suppressor of secY mutation [[cgsc_site:17848|CGSC]] | ||
| Line 1,646: | Line 1,943: | ||
| | | | ||
fts in reverse | fts in reverse | ||
| | |||
| | | | ||
Antisense RNA blocks ftsZ mRNA translation, inhibits cell division [[cgsc_site:36124|CGSC]] | Antisense RNA blocks ftsZ mRNA translation, inhibits cell division [[cgsc_site:36124|CGSC]] | ||
| Line 1,657: | Line 1,956: | ||
| | | | ||
Suppressor of transposase killing | Suppressor of transposase killing | ||
| | |||
| | | | ||
Suppresses cell aberrations and death caused by Tn5 transposase overexpression [[cgsc_site:36083|CGSC]] | Suppresses cell aberrations and death caused by Tn5 transposase overexpression [[cgsc_site:36083|CGSC]] | ||
| Line 1,668: | Line 1,969: | ||
| | | | ||
Suppressor of transposase killing | Suppressor of transposase killing | ||
| | |||
| | | | ||
Suppresses cell aberrations and death caused by Tn5 transposase overexpression [[cgsc_site:36093|CGSC]] | Suppresses cell aberrations and death caused by Tn5 transposase overexpression [[cgsc_site:36093|CGSC]] | ||
| Line 1,679: | Line 1,982: | ||
| | | | ||
Suppressor of transposase killing | Suppressor of transposase killing | ||
| | |||
| | | | ||
Suppresses cell aberrations and death caused by Tn5 transposase overexpression [[cgsc_site:36087|CGSC]] | Suppresses cell aberrations and death caused by Tn5 transposase overexpression [[cgsc_site:36087|CGSC]] | ||
| Line 1,690: | Line 1,995: | ||
| | | | ||
Suppressor of transposase killing | Suppressor of transposase killing | ||
| | |||
| | | | ||
Suppresses cell aberrations and death caused by Tn5 transposase overexpression [[cgsc_site:36090|CGSC]] | Suppresses cell aberrations and death caused by Tn5 transposase overexpression [[cgsc_site:36090|CGSC]] | ||
| Line 1,701: | Line 2,008: | ||
| | | | ||
Streptomycin | Streptomycin | ||
| | |||
| | | | ||
strB; low-level streptomycin resistance; modifies ribosome structure [[cgsc_site:149|CGSC]] | strB; low-level streptomycin resistance; modifies ribosome structure [[cgsc_site:149|CGSC]] | ||
| Line 1,712: | Line 2,021: | ||
| | | | ||
Streptomycin | Streptomycin | ||
| | |||
| | | | ||
asuF?; control of ribosomal ambiguity [[cgsc_site:148|CGSC]] | asuF?; control of ribosomal ambiguity [[cgsc_site:148|CGSC]] | ||
| Line 1,721: | Line 2,032: | ||
| | | | ||
84.7 | 84.7 | ||
| | |||
| | | | ||
| Line 1,734: | Line 2,047: | ||
| | | | ||
Suppressor heat-shock proteins | Suppressor heat-shock proteins | ||
| | |||
| | | | ||
Induction of heat shock genes [[cgsc_site:17839|CGSC]] | Induction of heat shock genes [[cgsc_site:17839|CGSC]] | ||
| Line 1,745: | Line 2,060: | ||
| | | | ||
T4 abortion | T4 abortion | ||
| | |||
| | | | ||
Mutants fail to support growth of T4 [[cgsc_site:125|CGSC]] | Mutants fail to support growth of T4 [[cgsc_site:125|CGSC]] | ||
| Line 1,756: | Line 2,073: | ||
| | | | ||
Trehalose, anaerobic | Trehalose, anaerobic | ||
| | |||
| | | | ||
Anaerobic growth on trehalose [[cgsc_site:37222|CGSC]] | Anaerobic growth on trehalose [[cgsc_site:37222|CGSC]] | ||
| Line 1,767: | Line 2,086: | ||
| | | | ||
Trehalose, anaerobic | Trehalose, anaerobic | ||
| | |||
| | | | ||
Anaerobic growth on trehalose [[cgsc_site:37910|CGSC]] | Anaerobic growth on trehalose [[cgsc_site:37910|CGSC]] | ||
| Line 1,778: | Line 2,099: | ||
| | | | ||
Transduction inhibition | Transduction inhibition | ||
| | |||
| | | | ||
Affects transduction, transformation, and rates of mutation [[cgsc_site:121|CGSC]] | Affects transduction, transformation, and rates of mutation [[cgsc_site:121|CGSC]] | ||
| Line 1,789: | Line 2,112: | ||
| | | | ||
Thiophene degradation | Thiophene degradation | ||
| | |||
| | | | ||
Degradation of furans and thiophenes; may be tlnA? [[cgsc_site:17824|CGSC]] | Degradation of furans and thiophenes; may be tlnA? [[cgsc_site:17824|CGSC]] | ||
| Line 1,800: | Line 2,125: | ||
| | | | ||
polarity suppressor | polarity suppressor | ||
| | |||
| | | | ||
PMID:8380152 | PMID:8380152 | ||
| Line 1,811: | Line 2,138: | ||
| | | | ||
Thiophene degradation | Thiophene degradation | ||
| | |||
| | | | ||
Degradation of furans and thiophenes [[cgsc_site:17821|CGSC]] | Degradation of furans and thiophenes [[cgsc_site:17821|CGSC]] | ||
| Line 1,822: | Line 2,151: | ||
| | | | ||
Thiophene degradation | Thiophene degradation | ||
| | |||
| | | | ||
Degradation of furans and thiophenes [[cgsc_site:15908|CGSC]] | Degradation of furans and thiophenes [[cgsc_site:15908|CGSC]] | ||
| Line 1,833: | Line 2,164: | ||
| | | | ||
acetate kinase | acetate kinase | ||
| | |||
| | | | ||
Ack- mutants were defective in aerobic growth on acetate or glucose as well as acetate accumulation from glucose & mapped near 39' (ackA mapped to ~50'). PMID:7033467 [[cgsc_site:19551|CGSC]] | Ack- mutants were defective in aerobic growth on acetate or glucose as well as acetate accumulation from glucose & mapped near 39' (ackA mapped to ~50'). PMID:7033467 [[cgsc_site:19551|CGSC]] | ||
| Line 1,844: | Line 2,177: | ||
| | | | ||
Thiolutin | Thiolutin | ||
| | |||
| | | | ||
tlnI; resistance or sensitivity to thiolutin; may be thdA? [[cgsc_site:102|CGSC]] | tlnI; resistance or sensitivity to thiolutin; may be thdA? [[cgsc_site:102|CGSC]] | ||
| Line 1,855: | Line 2,190: | ||
| | | | ||
alanine-glutamate transaminase | alanine-glutamate transaminase | ||
| | |||
| | | | ||
alaB was found to be capable of multi-copy suppression of an alanine auxotrophy. PMID:2890623 | alaB was found to be capable of multi-copy suppression of an alanine auxotrophy. PMID:2890623 | ||
| Line 1,866: | Line 2,203: | ||
| | | | ||
Tn migration | Tn migration | ||
| | |||
| | | | ||
Transposition of Tn9 and other transposons, development of phage Mu [[cgsc_site:100|CGSC]] | Transposition of Tn9 and other transposons, development of phage Mu [[cgsc_site:100|CGSC]] | ||
| Line 1,877: | Line 2,216: | ||
| | | | ||
D-galactose dehydrogenase | D-galactose dehydrogenase | ||
| | |||
| | | | ||
| Line 1,888: | Line 2,229: | ||
| | | | ||
Tolerance | Tolerance | ||
| | |||
| | | | ||
Bacteriocin tolerant; tolerance to colicins E2, E3, and ampicillin [[cgsc_site:96|CGSC]] | Bacteriocin tolerant; tolerance to colicins E2, E3, and ampicillin [[cgsc_site:96|CGSC]] | ||
| Line 1,899: | Line 2,242: | ||
| | | | ||
catabolic trehalose-6-phosphate phosphatase | catabolic trehalose-6-phosphate phosphatase | ||
| | |||
| | | | ||
In the absence of osmotic stress, trehalose induces converstion to free glucose and a glucose polymer, in a pathway involving TreE. PMID:8391102 | In the absence of osmotic stress, trehalose induces converstion to free glucose and a glucose polymer, in a pathway involving TreE. PMID:8391102 | ||
| Line 1,910: | Line 2,255: | ||
| | | | ||
Tolerance | Tolerance | ||
| | |||
| | | | ||
Bacteriocin tolerant; tolerance to colicins E2, E3, and ampicillin [[cgsc_site:95|CGSC]] | Bacteriocin tolerant; tolerance to colicins E2, E3, and ampicillin [[cgsc_site:95|CGSC]] | ||
| Line 1,921: | Line 2,268: | ||
| | | | ||
Tolerance | Tolerance | ||
| | |||
| | | | ||
Bacteriocin tolerant; sensitivity to colicins Ia and Ib [[cgsc_site:94|CGSC]] | Bacteriocin tolerant; sensitivity to colicins Ia and Ib [[cgsc_site:94|CGSC]] | ||
| Line 1,932: | Line 2,281: | ||
| | | | ||
Tolerance | Tolerance | ||
| | |||
| | | | ||
Bacteriocin tolerant; sensitivity to L, A, S4, E, and K [[cgsc_site:93|CGSC]] | Bacteriocin tolerant; sensitivity to L, A, S4, E, and K [[cgsc_site:93|CGSC]] | ||
| Line 1,943: | Line 2,294: | ||
| | | | ||
Thymine suppression modifier | Thymine suppression modifier | ||
| | |||
| | | | ||
Affects suppression efficiency for nonsense and frameshift mutations of Thy strains [[cgsc_site:36603|CGSC]] | Affects suppression efficiency for nonsense and frameshift mutations of Thy strains [[cgsc_site:36603|CGSC]] | ||
| Line 1,954: | Line 2,307: | ||
| | | | ||
Up-suppression? | Up-suppression? | ||
| | |||
| | | | ||
Efficiency of nonsense suppressors; see prfA | Efficiency of nonsense suppressors; see prfA | ||
| Line 1,967: | Line 2,322: | ||
| | | | ||
UV hyperresistant to UVC | UV hyperresistant to UVC | ||
| | |||
| | | | ||
Resistance to UVC, peroxide and antibiotics; may affect SOS repair PMID:8988611 [[cgsc_site:51073|CGSC]] | Resistance to UVC, peroxide and antibiotics; may affect SOS repair PMID:8988611 [[cgsc_site:51073|CGSC]] | ||
| Line 1,978: | Line 2,335: | ||
| | | | ||
UV sensitivity | UV sensitivity | ||
| | |||
| | | | ||
UV-sensitive mutants, locus linked to uvr PMID:8988611 [[cgsc_site:51076|CGSC]] | UV-sensitive mutants, locus linked to uvr PMID:8988611 [[cgsc_site:51076|CGSC]] | ||
| Line 1,984: | Line 2,343: | ||
|-class='sortbottom' | |-class='sortbottom' | ||
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Revision as of 02:36, 2 August 2009
This page has a list of genes that are described in the 1998 linkage map for E. coli K-12 (Edition 10)[1] but have not been correlated with a gene in EcoliWiki. In most cases, the alleles that led to assignment of these gene names are likely to affect known genes, but which gene has not been determined.
| Gene | Approx. Map Location | Mnemonic | Paper(s) describine gene | Notes | Candidate gene(s) |
|---|---|---|---|---|---|
|
abpS |
63.5 |
Arg binding protein |
Low-affinity transport system for arginine and ornithine; periplasmic binding protein CGSC |
||
|
abs |
94.1 |
Antibiotic sensitivity |
Sensitivity and permeability to antibiotics and dyes CGSC |
||
|
acpX |
43.9 |
Acyl carrier protein |
acpS; originally thought to be holo-ACP synthase; perhaps cryptic second gene or regulator CGSC |
||
|
acrC |
4.5 |
Acridine |
Sensitivity to acriflavine; transmembrane protein CGSC |
||
|
adhB |
19.1 |
Alcohol dehydrogenase |
Alcohol dehydrogenase CGSC |
||
|
aga |
70.7 |
Acetylgalactosamine |
Cluster of putative N-acetylgalactosamine pathway genes, including the kba gene, and mannose permease homologs CGSC |
||
|
aroI |
84.2 |
Aromatic |
Function unknown CGSC |
||
|
azaA |
44.6 |
Azaserine |
Mutants azaserine resistant CGSC |
||
|
azaB |
71.9 |
Azaserine |
Mutants azaserine resistant CGSC |
||
|
azl |
58.1 |
Azaleucine |
Mutants azaleucine resistant; regulates ilv and leu CGSC |
||
|
bfm |
85.9 |
BF23 multiplication |
Controls phage BF23 multiplication CGSC |
||
|
bglT |
84.9 |
-Glucoside |
bglE; regulatory gene for BglA CGSC |
||
|
bioP |
86.6 |
Biotin |
bir, birB; biotin transport CGSC |
||
|
brnR |
8.5 |
Branched chain |
Mutants valine resistant, glycylvaline sensitive CGSC |
||
|
brnS |
1.2 |
Branched chain |
Mutants valine resistant, glycylvaline sensitive CGSC |
||
|
brnT |
65.2 |
Branched chain |
Low-affinity transport of Ile CGSC |
||
|
bymA |
93.2 |
Bypass maltose |
Growth on maltose in MalT cells CGSC |
||
|
calA |
95.0 |
Calcium |
Calcium-proton antiport activity CGSC |
||
|
calC |
15.2 |
Calcium |
Calcium transport; mutants defective in chemotaxis CGSC |
||
|
calD |
9.4 |
Calcium |
Calcium transport; mutants defective in chemotaxis CGSC |
||
|
cdsS |
71.7 |
CDP diglyceride synthase |
Stability of CDP diglyceride synthase CGSC |
||
|
cpsA |
45.4 |
Capsular polysaccharide synthesis |
Colanic acid (CPS) biosynthesis CGSC |
||
|
cpsC |
45.8 |
Capsular polysaccharide synthesis |
Colanic acid (CPS) biosynthesis CGSC |
||
|
cpsD |
45.8 |
Capsular polysaccharide synthesis |
Colanic acid (CPS) biosynthesis CGSC |
||
|
cpsE |
45.8 |
Capsular polysaccharide synthesis |
Colanic acid (CPS) biosynthesis CGSC |
||
|
cpsF |
90.2 |
Capsular polysaccharide synthesis |
Colanic acid (CPS) biosynthesis CGSC |
||
|
cpxB |
41.3 |
Conjugative plasmid expression |
Phage Q resistance, membrane protein CGSC |
||
|
crg |
28.8 |
Cold resistant growth |
Allows cold-resistant growth CGSC |
||
|
csiA |
85.3 |
Carbon starvation induced |
Stationary phase inducible protein CGSC |
||
|
csiB |
17.4 |
Carbon starvation induced |
Stationary phase inducible protein CGSC |
||
|
csiC |
66.0 |
Carbon starvation induced |
Stationary phase inducible protein CGSC |
||
|
csiF |
8.6 |
Carbon starvation induced |
Stationary phase inducible protein CGSC |
||
|
cup |
97.0 |
Carbohydrate uptake |
Mutants have defective carbohydrate uptake CGSC |
||
|
cxm |
6.3 |
Carbon-xylose metabolism |
cxr; methyl glyoxal synthesis; D-xylose utilization CGSC |
||
|
cysX |
81.5 |
Cysteine |
Reading frame in opposite orientation within cysE gene; polypeptide synthesized in maxicells CGSC |
||
|
dadQ |
98.9 |
D-Amino acid dehydrogenase |
alnR; regulator of dad regulon CGSC |
||
|
dctB |
16.4 |
Dicarboxylic acid transport |
Uptake of C-4 dicarboxylic acids; 3-fluoromalate resistance, D-tartrate resistant CGSC |
||
|
del |
64.3 |
Deletion |
Affects frequency of IS1-mediated deletions; 1,000-fold reduction in deletion frequency CGSC |
||
|
dgkR |
93.7 |
Diglyceride kinase |
Regulatory CGSC |
||
|
dinY |
41.9 |
Damage inducible |
Repair gene CGSC |
||
|
dnaI |
40.3 |
DNA |
DNA biosynthesis CGSC |
||
|
dppG |
14.0 |
Dipeptide permease |
Uptake of dipeptides; dipeptide permease CGSC |
||
|
dvl |
7.4 |
Dye-visible light? |
Sensitivity to SDS and toluidine blue plus light CGSC |
||
|
ebgB |
69.5 |
Evolved -galactosidase |
Cryptic -galactoside utilization, possible paralog of lacY CGSC |
||
|
envN |
4.2 |
Envelope |
Affects envelope; defects osmotically remedied CGSC |
||
|
envP |
90.4 |
Envelope |
Affects envelope; defects osmotically remedied CGSC |
||
|
envQ |
60.7 |
Envelope |
Affects envelope; defects osmotically remedied CGSC |
||
|
envT |
14.2 |
Envelope |
Affects envelope; defects osmotically remedied CGSC |
||
|
epp |
E-pentapeptide |
Minigene within 23S rRNA encoding functional pentapeptide; erythromycin resistance CGSC |
|||
|
esp |
17.3 |
Efficiency site for phage |
Site for efficient packaging of phage T1 CGSC |
||
|
exbC |
61.5 |
Export |
Uptake of enterochelin; resistance or sensitivity to colicins CGSC |
||
|
expA |
22.2 |
Export |
Expression of a group of export proteins CGSC |
||
|
fatA |
71.7 |
Fatty acid |
Utilization of trans unsaturated fatty acids CGSC |
||
|
fcsA |
86.9 |
Filamentous, cold sensitive |
Cold-sensitive cell division mutant CGSC |
||
|
fexB |
86.7 |
F exclusion |
Affects ArcA phenotype CGSC |
||
|
fhlB |
95.1 |
Formate hydrogen-lyase |
Formate hydrogen-lyase; activated by fhlA CGSC |
||
|
fipB |
86.0 |
F1 phage |
Morphogenesis of phage F1 CGSC |
||
|
fipC |
75.0 |
F1 phage |
Morphogenesis of phage F1 CGSC |
||
|
flkB |
95.4 |
FKBP-like |
Periplasmic PPIase, of FK506-binding protein type (EC 5.2.1.8); contains pipecolic acid residue CGSC |
||
|
gadR |
79.6 |
Glutamate deCase |
Regulatory gene for gat? CGSC |
||
|
garA |
15.8 |
Glucarate |
D-Glucarate utilization CGSC |
||
|
garB |
3.6 |
Glucarate |
D-Glucarate utilization CGSC |
||
|
glmX |
26.2 |
Glucosamine |
Affects suppression of glmS mutations by nagB CGSC |
||
|
gltE |
81.4 |
Glutamate |
Glutamyl-tRNA synthetase; possible regulatory subunit CGSC |
||
|
gltH |
21.8 |
Glutamate |
Growth on glutamate CGSC |
||
|
gltR |
92.3 |
Glutamate |
Growth on glutamate at 42C CGSC |
||
|
gprA |
0.3 |
Growth of phage, replication |
Replication of certain lambdoid phage CGSC |
||
|
gprB |
0.2 |
Growth of phage, replication |
Replication of certain lambdoid phage CGSC |
||
|
gurC |
18.0 |
Glucuronide |
Utilization of glucuronides CGSC |
||
|
het |
84.6 |
Heterogeneous size |
cop; possibly structural gene for DNA-binding protein; near ori CGSC |
||
|
hslC |
19.9 |
Heat shock locus |
Protein expressed as heat shock regulon member CGSC |
||
|
hslD |
24.1 |
Heat shock locus |
Protein expressed as heat shock regulon member CGSC |
||
|
hslK |
40.7 |
Heat shock locus |
Protein expressed as heat shock regulon member CGSC |
||
|
hslW |
94.2 |
Heat shock locus |
Heat-inducible; regulatory gene, near groE CGSC |
||
|
ilvF |
57.0 |
Isoleucine-valine (requirement) |
Production of valine-resistant acetolactate synthase activity CGSC |
||
|
ilvR |
99.9 |
Isoleucine-valine |
|||
|
ilvU |
6.4 |
Isoleucine-valine (requirement) |
Regulation of ileS and modification of Ile tRNA2 and Val tRNA2 CGSC |
||
|
inm |
79.0 |
Insensitive NG mutagenesis |
Susceptibility to mutagenesis by nitrosoguanidine CGSC |
||
|
isfA |
86.0 |
Inhibits SOS function |
Regulatory gene; SOS-related CGSC |
||
|
ksgB |
37.7 |
Kasugamycin |
High-level resistance to kasugamycin CGSC |
||
|
ksgC |
12.0 |
Kasugamycin |
Resistance to kasugamycin; affects ribosomal protein S2 CGSC |
||
|
ksgD |
30.9 |
Kasugamycin |
Resistance to kasugamycin CGSC |
||
|
leuJ |
13.7 |
Leucine (biosynthesis) |
flr; regulation of leu and ilv operons CGSC |
||
|
leuR |
79.3 |
Leucine |
Regulates level of leucyl-tRNA synthetase CGSC |
||
|
leuY |
9.5 |
Leucine |
Regulates level of leucyl-tRNA synthetase CGSC |
||
|
lev |
9.0 |
Levallorphan |
Resistance to levallorphan CGSC |
||
|
linB |
29.3 |
Lincomycin |
High-level lincomycin resistance CGSC |
||
|
lpcB |
68.0 |
Lipopolysaccharide core |
mrc, pon; T-phage resistance, novobiocin sensitivity CGSC |
||
|
lrb |
7.3 |
L-Ribose (utilization) |
Affects NADPH-linked L-ribose reductase activity CGSC |
||
|
lysX |
63.3 |
Lysine |
Lysine excretion CGSC |
||
|
lytA |
60.6 |
Lytic |
Tolerance to -lactams; autolysis CGSC |
||
|
mafA |
0.9 |
Maintenance of F |
Maintenance of F-like plasmids CGSC |
||
|
mafB |
1.9 |
Maintenance of F |
Maintenance of F-like plasmids CGSC |
||
|
mbrB |
88.6 |
Mothball resistant |
Resistance to camphor vapors; coupling of cell division and replication, growth rate and partitioning CGSC |
||
|
meb |
78.7 |
malE bypass |
Suppressor of malE secB-defective transport of mal-binding protein CGSC |
||
|
mglR |
16.9 |
Methyl-galactoside |
R-MG; regulatory gene CGSC |
||
|
mng |
40.0 |
Manganese |
Manganese resistance CGSC |
||
|
mraA |
2.0 |
Murein cluster a |
D-Alanine carboxypeptidase CGSC |
||
|
mul |
83.1 |
Mutability lambda |
Mutability in UV-radiated lambda phage CGSC |
||
|
murH |
99.3 |
Murein |
Terminal stage in peptidoglycan synthesis, incorporating disaccharide peptide units into wall CGSC |
||
|
mutG |
43.7 |
Mutator |
Mutation causes high C-to-T mutation in second C of CCAGG; near but distinct from vsr; provisionally termed mutG CGSC |
||
|
nalB |
60.2 |
Nalidixic acid |
Sensitivity to nalidixic acid (NAL) CGSC |
||
|
neaB |
75.0 |
Neamine |
Neamine sensitivity CGSC |
||
|
nfnA |
80.8 |
Nitrofurantoin |
Nitrofurantoin sensitivity CGSC |
||
|
nfrD |
54.2 |
N4 (phage) resistant |
Phage N4 susceptibility CGSC |
||
|
non |
45.7 |
Nonmucoid |
Affects capsule formation CGSC |
||
|
oppE |
98.9 |
Oligopeptide permease |
Oligopeptide transport CGSC |
||
|
opr |
19.0 |
rpo reversed |
Rate of degradation of aberrant RNAP-subunit proteins CGSC |
||
|
ops |
66.1 |
Overproduction of polysaccharide |
Level of exopolysaccharide production CGSC |
||
|
oriJ |
30.5 |
Origin of replication |
Locus in defective prophage rac CGSC |
||
|
pac |
31.0 |
Phenylacetate |
Phenylacetate degradation CGSC |
||
|
phxB |
17.0 |
Phage X |
Adsorption of X154 CGSC |
||
|
poaR |
65.9 |
Proline oxidase |
Regulation of proline oxidase production CGSC |
||
|
popD |
0.2 |
Porphyrin |
5-Aminolevulinate dehydratase (EC 4.2.1.24) CGSC |
||
|
prlZ |
71.4 |
Protein localization |
Suppresses export defects in signal sequence mutations CGSC |
||
|
proT |
83.8 |
Proline |
Proline transport carrier protein, putative CGSC |
||
|
pus |
20.6 |
Reverse of sup (amber) |
Reverses accentuation effects of amber suppressor on relB mutations CGSC |
||
|
qin |
35.1 |
Q independent |
kim; cryptic lambdoid phage CGSC |
||
|
qmeC |
75.3 |
Q membrane |
Glycine resistance; penicillin sensitivity; membrane defect CGSC |
||
|
qmeD |
64.4 |
Q membrane |
Glycine resistance; penicillin sensitivity; membrane defect CGSC |
||
|
qmeE |
37.9 |
Q membrane |
Glycine resistance; penicillin sensitivity; membrane defect CGSC |
||
|
ras |
9.9 |
Radiation sensitive |
Sensitive to X rays and UV CGSC |
||
|
rdgA |
16.1 |
RecA-dependent growth |
Dependence of growth upon recA gene product CGSC |
||
|
relX |
62.8 |
Relaxed |
Control of ppGpp synthesis CGSC |
||
|
rer |
89.9 |
Resistance to radiation |
Resistance to UV and gamma radiation CGSC |
||
|
ridA |
73.1 |
Rifampin dependence |
Rifampin resistance and dependence CGSC |
||
|
ridB |
85.5 |
Rifampin dependence |
Transcription and translation; rifampin (rifamycin) sensitivity CGSC |
rho | |
|
rimB |
38.9 |
Ribosomal modification |
50S ribosomal subunit maturation CGSC |
||
|
rimC |
26.2 |
Ribosomal modification |
50S ribosomal subunit maturation CGSC |
||
|
rimD |
87.7 |
Ribosomal modification |
50S ribosomal subunit maturation CGSC |
||
|
rimE |
74.1 |
Ribosomal modification |
Ribosomal protein modification CGSC |
||
|
rimH |
13.6 |
Ribosomal modification |
stsB; ribosomal modification CGSC |
||
|
rit |
89.2 |
Ribosomal thermolability |
Affects thermolability of 50S ribosomal subunit CGSC |
||
|
rorB |
85.1 |
Roentgen resistance |
Sensitivity to ionizing radiation, mitomycin C CGSC |
||
|
sds |
30.4 |
Suppresses disulfide bond |
Motility defects CGSC |
||
|
semA |
40.5 |
Sensitivity to microcin |
Sensitivity to microcin E492 CGSC |
||
|
serR |
2.3 |
Serine |
Regulates level of seryl-tRNA synthetase CGSC |
||
|
sfiC |
25.8 |
Septum formation inhibition |
Element of e14, inhibitor of cell division CGSC |
||
|
sipC |
82.6 |
Suppressor of increased permeability |
Mutations reverse the susceptibility to vancomycin and other hydrophobic antibiotics caused by TraT plasmid gene CGSC |
||
|
sipD |
82.7 |
Suppressor of increased permeability |
Same phenotype as that produced by sipC CGSC |
||
|
sir |
61.2 |
SOS-independent repair |
SOS-independent repair of mitomycin C-induced DNA damage CGSC |
||
|
sloB |
75.0 |
Slow growth |
Tolerance for amidinopenicillin and nalidixic acid; slow growth rate CGSC |
||
|
slrR |
60.9 |
Sorbitol |
gutR; regulatory gene for srl CGSC |
||
|
srnA |
9.4 |
Stable RNA |
Degradation of stable RNA CGSC |
||
|
ssaE |
52.5 |
Suppression secA |
Suppresses secA mutations CGSC |
||
|
ssaG |
41.8 |
Suppression secA |
Suppresses secA mutations CGSC |
||
|
ssaH |
94.1 |
Suppression secA |
Suppresses secA mutations CGSC |
||
|
ssyD |
3.0 |
Suppression of secY |
Suppressor of secY mutation CGSC |
||
|
stfZ |
2.3 |
fts in reverse |
Antisense RNA blocks ftsZ mRNA translation, inhibits cell division CGSC |
||
|
stkA |
77.5 |
Suppressor of transposase killing |
Suppresses cell aberrations and death caused by Tn5 transposase overexpression CGSC |
||
|
stkB |
86.1 |
Suppressor of transposase killing |
Suppresses cell aberrations and death caused by Tn5 transposase overexpression CGSC |
||
|
stkC |
98.5 |
Suppressor of transposase killing |
Suppresses cell aberrations and death caused by Tn5 transposase overexpression CGSC |
||
|
stkD |
28.6 |
Suppressor of transposase killing |
Suppresses cell aberrations and death caused by Tn5 transposase overexpression CGSC |
||
|
strC |
7.0 |
Streptomycin |
strB; low-level streptomycin resistance; modifies ribosome structure CGSC |
||
|
strM |
78.3 |
Streptomycin |
asuF?; control of ribosomal ambiguity CGSC |
||
|
stsA |
84.7 |
Altered RNase activity CGSC |
|||
|
suhA |
78.4 |
Suppressor heat-shock proteins |
Induction of heat shock genes CGSC |
||
|
tabC |
86.3 |
T4 abortion |
Mutants fail to support growth of T4 CGSC |
||
|
tanA |
41.6 |
Trehalose, anaerobic |
Anaerobic growth on trehalose CGSC |
||
|
tanB |
68.1 |
Trehalose, anaerobic |
Anaerobic growth on trehalose CGSC |
||
|
tdi |
4.3 |
Transduction inhibition |
Affects transduction, transformation, and rates of mutation CGSC |
||
|
thdA |
10.5 |
Thiophene degradation |
Degradation of furans and thiophenes; may be tlnA? CGSC |
||
|
psu |
1.3 min |
polarity suppressor |
|||
|
thdC |
94.2 |
Thiophene degradation |
Degradation of furans and thiophenes CGSC |
||
|
thdD |
99.8 |
Thiophene degradation |
Degradation of furans and thiophenes CGSC |
||
|
ackB |
39 min |
acetate kinase |
Ack- mutants were defective in aerobic growth on acetate or glucose as well as acetate accumulation from glucose & mapped near 39' (ackA mapped to ~50'). PMID:7033467[6] CGSC |
||
|
tlnA |
10.5 |
Thiolutin |
tlnI; resistance or sensitivity to thiolutin; may be thdA? CGSC |
||
|
alaB |
alanine-glutamate transaminase |
alaB was found to be capable of multi-copy suppression of an alanine auxotrophy. PMID:2890623[7] |
|||
|
tnm |
92.0 |
Tn migration |
Transposition of Tn9 and other transposons, development of phage Mu CGSC |
||
|
dgd |
D-galactose dehydrogenase |
||||
|
tolD |
22.9 |
Tolerance |
Bacteriocin tolerant; tolerance to colicins E2, E3, and ampicillin CGSC |
||
|
treE |
catabolic trehalose-6-phosphate phosphatase |
In the absence of osmotic stress, trehalose induces converstion to free glucose and a glucose polymer, in a pathway involving TreE. PMID:8391102[8] |
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|
tolE |
22.9 |
Tolerance |
Bacteriocin tolerant; tolerance to colicins E2, E3, and ampicillin CGSC |
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|
tolI |
0.1 |
Tolerance |
Bacteriocin tolerant; sensitivity to colicins Ia and Ib CGSC |
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|
tolJ |
0.1 |
Tolerance |
Bacteriocin tolerant; sensitivity to L, A, S4, E, and K CGSC |
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|
tsmA |
40.1 |
Thymine suppression modifier |
Affects suppression efficiency for nonsense and frameshift mutations of Thy strains CGSC |
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|
ups |
27.1 |
Up-suppression? |
Efficiency of nonsense suppressors; see prfA PMID:6265322[9] CGSC |
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|
uvh |
90.2 |
UV hyperresistant to UVC |
Resistance to UVC, peroxide and antibiotics; may affect SOS repair PMID:8988611[10] CGSC |
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|
uvs |
91.1 |
UV sensitivity |
UV-sensitive mutants, locus linked to uvr PMID:8988611[10] CGSC |
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| edit table |
References
See Help:References for how to manage references in EcoliWiki.
- ↑ Berlyn, MK (1998) Linkage map of Escherichia coli K-12, edition 10: the traditional map. Microbiol. Mol. Biol. Rev. 62 814-984 PubMed
- ↑ 2.0 2.1 Guardiola, J et al. (1974) Mutations affecting the different transport systems for isoleucine, leucine, and valine in Escherichia coli K-12. J. Bacteriol. 117 393-405 PubMed
- ↑ Wada, C et al. (1977) Replication of Fpoh+ plasmid in mafA mutants of Escherichia coli defective in plasmid maintenance. Mol. Gen. Genet. 152 211-7 PubMed
- ↑ 4.0 4.1 Wada, C & Yura, T (1979) Escherichia coli mutants incapable of supporting replication of F-like plasmids at high temperature: isolation and characterization of mafA and mafB mutants. J. Bacteriol. 140 864-73 PubMed
- ↑ Ephrati-Elizur, E (1993) A mutation in a new gene of Escherichia coli, psu, requires secondary mutations for survival: psu mutants express a pleiotropic suppressor phenotype. J. Bacteriol. 175 207-13 PubMed
- ↑ Pascal, MC et al. (1981) Mutants of Escherichia coli K12 with defects in anaerobic pyruvate metabolism. J. Gen. Microbiol. 124 35-42 PubMed
- ↑ Wang, MD et al. (1987) Cloning of genes that suppress an Escherichia coli K-12 alanine auxotroph when present in multicopy plasmids. J. Bacteriol. 169 5610-4 PubMed
- ↑ Strøm, AR & Kaasen, I (1993) Trehalose metabolism in Escherichia coli: stress protection and stress regulation of gene expression. Mol. Microbiol. 8 205-10 PubMed
- ↑ Cowman, A & Beacham, IR (1980) Molecular cloning of the gene (ush) from Escherichia coli specifying periplasmic UDP-sugar hydrolase (5'-nucleotidase). Gene 12 281-6 PubMed
- ↑ 10.0 10.1 Ahmad, SI (1996) A mutant of Escherichia coli hyper-resistant to a number of DNA damaging agents: location of the mutational site. J. Photochem. Photobiol. B, Biol. 36 47-53 PubMed