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Standard Name


Gene Synonym(s)

ECK0060, b0059, JW0058, rapA, yabA, hepA[1], hepA, yabA

Product Desc.

RNA Polymerase (RNAP)-binding ATPase and RNAP recycling factor[2][3]

RNA polymerase binding protein; mutants are UV-S; mutant biofilms have less polysaccharide and are antibiotic sensitive; ATPase and putative helicase[4]

Product Synonyms(s)

RNA polymerase-associated helicase protein (ATPase and RNA polymerase recycling factor)[1], B0059[2][1], YabA[2][1], RapA[2][1], RapA[2][1] , ECK0060, hepA, JW0058, yabA, b0059

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): rluA[2], rapA[2]

Quick Links

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HepA has sequence similarity to SWI2/SNF2 helicases. hepA is downstream of polB, but is not under lexA control. The mutant phentypes may be indirect since other genes, e.g. yeeZ and aaeA(yhcQ), are downregulated in hepA(rapA) mutants (Lynch, 2007).[4]


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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.