tqsA:Gene Product(s): Difference between revisions

Standard name	YdgG
Synonyms	predicted inner membrane protein^[1], B1601^[2]^[1], YdgG^[2]^[1], TqsA^[2]^[1]
Product description	transporter of quorum signal AI-2^[2]^[3] Pheromone AI-2 transporter; mutants have increased intracellular AI-2 and decreased extracellular AI-2; controls biofilm formation^[4]
EC number (for enzymes)
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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier	GO ID	GO term name	Reference(s)	Evidence Code	with/from	Aspect	Notes	Status
	GO:0016021	integral to membrane	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0812	C	Seeded from EcoCyc ^[5]	complete
	GO:0016020	membrane	GO_REF:0000004 GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0397 SP_KW:KW-0472	C	Seeded from EcoCyc 12.5 ^[6]	complete
	GO:0006810	transport	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0813	P	Seeded from EcoCyc	complete
	GO:0005886	plasma membrane	GO_REF:0000004 GO_REF:0000004 GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_KW:KW-0997 SP_KW:KW-1003 SP_SL:SL-0037	C	Seeded from EcoCyc ^[5]	complete
	GO:0009372	quorum sensing	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0673	P	Seeded from EcoCyc ^[5]	complete
	GO:0005886	plasma membrane	GO_REF:0000004 GO_REF:0000004 GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_KW:KW-0997 SP_KW:KW-1003 SP_SL:SL-0037	C	Seeded from EcoCyc	complete
	GO:0009372	quorum sensing	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0673	P	Seeded from EcoCyc	complete
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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type	Partner	Notes	References	Evidence
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment	Description	Evidence	Notes
plasma membrane	C-terminus localized in the cytoplasm with 8 predicted transmembrane domains	Daley et al. (2005) ^[7]
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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence	at EcoCyc MAKPIITLNG LKIVIMLGML VIILCGIRFA AEIIVPFILA LFIAVILNPL VQHMVRWRVP RVLAVSILMT IIVMAMVLLL AYLGSALNEL TRTLPQYRNS IMTPLQALEP LLQRVGIDVS VDQLAHYIDP NAAMTLLTNL LTQLSNAMSS IFLLLLTVLF MLLEVPQLPG KFQQMMARPV EGMAAIQRAI DSVSHYLVLK TAISIITGLV AWAMLAALDV RFAFVWGLLA FALNYIPNIG SVLAAIPPIA QVLVFNGFYE ALLVLAGYLL INLVFGNILE PRIMGRGLGL STLVVFLSLI FWGWLLGPVG MLLSVPLTII VKIALEQTAG GQSIAVLLSD LNKE
Length	344
Mol. Wt	37.54 kDa (calc) ^[2]
pI
Extinction coefficient	37930 - 38055 (calc based on 7 Y, 5 W, and 1 C residues)
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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type	Residues	Description	Notes
Domain	62 - 84	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[8]
Domain	144 - 166	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[8]
Domain	196 - 218	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[8]
Domain	222 - 244	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[8]
Domain	257 - 279	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[8]
Domain	299 - 321	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[8]
Domain	7 - 29	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[8]
Domain	33 - 55	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[8]
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<motif_map/>

Click the image to view raw output from TMHMM.

Structure See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

Models

View models at:

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type	Source	Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database	Accession	Notes
EcoCyc (EcoliWiki Page)	EcoCyc:G6859-MONOMER
UniProt (EcoliWiki Page)	UniProt:P0AFS5
PFAM (EcoliWiki Page)	PFAM:PF01594
RefSeq (EcoliWiki Page)	RefSeq:NP_416118
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Notes

Links

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Name	URL	Comments
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References

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↑ ^1.0 ^1.1 ^1.2 ^1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
↑ ^5.0 ^5.1 ^5.2 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
↑ EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ Daley, DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308 1321-3 PubMed
↑ ^8.0 ^8.1 ^8.2 ^8.3 ^8.4 ^8.5 ^8.6 ^8.7 Krogh, A et al. (2001) Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. J. Mol. Biol. 305 567-80 PubMed

tqsA:Gene Product(s): Difference between revisions

Revision as of 07:39, 22 May 2009

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

Links

References

Categories

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 Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
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+complete
+|-
+|
+|
+GO:0006810
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+transport
+|
+GO_REF:0000004
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+IEA: Inferred from Electronic Annotation
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+SP_KW:KW-0813
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+P
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+Seeded from EcoCyc
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 complete
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-GO:0006810
+GO:0009372
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-transport
+quorum sensing
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 GO_REF:0000004
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 IEA: Inferred from Electronic Annotation
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-SP_KW:KW-0813
+SP_KW:KW-0673
 |
 P

tqsA:Gene Product(s): Difference between revisions

Revision as of 07:39, 22 May 2009

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

Links

References

Categories

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