exuT:Gene Product(s): Difference between revisions

Standard name	ExuT
Synonyms	hexuronate transporter^[1], B3093^[2]^[1], ExuT^[2]^[1]
Product description	ExuT hexuronate MFS transporter^[2]^[3] Hexuronate permease, for glucuronate and galacturonate^[4]
EC number (for enzymes)
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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier	GO ID	GO term name	Reference(s)	Evidence Code	with/from	Aspect	Notes	Status
	GO:0016021	integral to membrane	GO_REF:0000002 GO_REF:0000002 GO_REF:0000004	IEA: Inferred from Electronic Annotation	InterPro:IPR004744 InterPro:IPR007114 SP_KW:KW-0812	C	Seeded from EcoCyc ^[5]	complete
	GO:0016020	membrane	GO_REF:0000004 GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0397 SP_KW:KW-0472	C	Seeded from EcoCyc 12.5 ^[6]	complete
	GO:0006810	transport	GO_REF:0000002 GO_REF:0000002 GO_REF:0000004	IEA: Inferred from Electronic Annotation	InterPro:IPR004744 InterPro:IPR007114 SP_KW:KW-0813	P	Seeded from EcoCyc ^[5]	complete
	GO:0005215	transporter activity	GO_REF:0000002 GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR004744 InterPro:IPR007114	F	Seeded from EcoCyc ^[5]	complete
	GO:0019698	D-galacturonate catabolic process	PMID:6450743^[7]	IMP: Inferred from Mutant Phenotype		P	Seeded from EcoCyc ^[5]	complete
	GO:0015292	uniporter activity				F	Seeded from EcoCyc 11.1^[3].	required fields missing
	GO:0005886	plasma membrane	GO_REF:0000004 GO_REF:0000004 GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_KW:KW-0997 SP_KW:KW-1003 SP_SL:SL-0037	C	Seeded from EcoCyc ^[5]	complete
	GO:0005215	transporter activity	GO_REF:0000002 GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR004744 InterPro:IPR007114	F	Seeded from EcoCyc	complete
	GO:0005886	plasma membrane	GO_REF:0000004 GO_REF:0000004 GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_KW:KW-0997 SP_KW:KW-1003 SP_SL:SL-0037	C	Seeded from EcoCyc	complete
	GO:0016052	carbohydrate catabolic process				P	Seeded from EcoCyc 11.1^[3].	required fields missing
	GO:0006810	transport	GO_REF:0000002 GO_REF:0000002 GO_REF:0000004	IEA: Inferred from Electronic Annotation	InterPro:IPR004744 InterPro:IPR007114 SP_KW:KW-0813	P	Seeded from EcoCyc	complete
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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type	Partner	Notes	References	Evidence
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment	Description	Evidence	Notes
plasma membrane	C-terminus localized in the cytoplasm with 11 predicted transmembrane domains	Daley et al. (2005) ^[8]
plasma membrane			From EcoCyc^[3]
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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence	at EcoCyc MATFGACRFF FGYPVVTNIF SLWRDDGRAS CGYNKTMRFY MRKIKGLRWY MIALVTLGTV LGYLTRNTVA AAAPTLMEEL NISTQQYSYI IAAYSAAYTV MQPVAGYVLD VLGTKIGYAM FAVLWAVFCG ATALAGSWGG LAVARGAVGA AEAAMIPAGL KASSEWFPAK ERSIAVGYFN VGSSIGAMIA PPLVVWAIVM HSWQMAFIIS GALSFIWAMA WLIFYKHPRD QKHLTDEERD YIINGQEAQH QVSTAKKMSV GQILRNRQFW GIALPRFLAE PAWGTFNAWI PLFMFKVYGF NLKEIAMFAW MPMLFADLGC ILGGYLPPLF QRWFGVNLIV SRKMVVTLGA VLMIGPGMIG LFTNPYVAIM LLCIGGFAHQ ALSGALITLS SDVFGRNEVA TANGLTGMSA WLASTLFALV VGALADTIGF SPLFAVLAVF DLLGALVIWT VLQNKPAIEV AQETHNDPAP QH
Length	472
Mol. Wt	51.57 kDa (calc) ^[2]
pI
Extinction coefficient	113330 - 113955 (calc based on 17 Y, 16 W, and 5 C residues)
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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type	Residues	Description	Notes
Domain	430 - 452	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[9]
Domain	47 - 66	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[9]
Domain	87 - 109	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[9]
Domain	119 - 141	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[9]
Domain	176 - 198	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[9]
Domain	203 - 225	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[9]
Domain	272 - 294	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[9]
Domain	309 - 331	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[9]
Domain	344 - 363	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[9]
Domain	368 - 390	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[9]
Domain	403 - 425	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[9]
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<motif_map/>

Click the image to view raw output from TMHMM.

Structure See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

Models

View models at:

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type	Source	Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database	Accession	Notes
EcoCyc (EcoliWiki Page)	EcoCyc:EXUT-MONOMER
UniProt (EcoliWiki Page)	UniProt:P0AA78
PFAM (EcoliWiki Page)	PFAM:PF07690
RefSeq (EcoliWiki Page)	RefSeq:NP_417564
ModBase (EcoliWiki Page)	ModBase:P0AA78
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Notes

Links

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Name	URL	Comments
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References

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↑ ^1.0 ^1.1 ^1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
↑ ^2.0 ^2.1 ^2.2 ^2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ ^3.0 ^3.1 ^3.2 ^3.3 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
↑ ^5.0 ^5.1 ^5.2 ^5.3 ^5.4 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
↑ EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ Ritzenthaler, P et al. (1981) Molecular cloning of Escherichia coli K-12 hexuronate system genes: exu region. J. Bacteriol. 145 181-90 PubMed
↑ Daley, DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308 1321-3 PubMed
↑ ^9.00 ^9.01 ^9.02 ^9.03 ^9.04 ^9.05 ^9.06 ^9.07 ^9.08 ^9.09 ^9.10 Krogh, A et al. (2001) Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. J. Mol. Biol. 305 567-80 PubMed

exuT:Gene Product(s): Difference between revisions

Revision as of 00:04, 22 May 2009

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

Links

References

Categories

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@@ Line 226: / Line 226: @@
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 F
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+Seeded from EcoCyc
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+complete
+|-
+|
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+GO:0005886
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+plasma membrane
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+GO_REF:0000004<br />GO_REF:0000004<br />GO_REF:0000023
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+IEA: Inferred from Electronic Annotation
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+SP_KW:KW-0997<br />SP_KW:KW-1003<br />SP_SL:SL-0037
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+C
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 Seeded from EcoCyc
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-GO:0005886
+GO:0006810
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-plasma membrane
+transport
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-GO_REF:0000004<br />GO_REF:0000004<br />GO_REF:0000023
+GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000004
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 IEA: Inferred from Electronic Annotation
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-SP_KW:KW-0997<br />SP_KW:KW-1003<br />SP_SL:SL-0037
+InterPro:IPR004744<br />InterPro:IPR007114<br />SP_KW:KW-0813
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-C
+P
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 Seeded from EcoCyc

exuT:Gene Product(s): Difference between revisions

Revision as of 00:04, 22 May 2009

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

Links

References

Categories

Navigation menu

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