metI:Gene Product(s): Difference between revisions

Standard name	MetI
Synonyms	DL-methionine transporter subunit^[1], membrane component protein of ABC superfamily^[1], B0198^[2]^[1], MetD^[2]^[1], MetI^[2]^[1], YaeE^[2]^[1]
Product description	MetI^[2]^[3]; Component of L- and D-methionine uptake ABC permease^[2]^[3] L,D-methionine transporter, membrane permease component; methionine sulfoximine sensitivity^[4]
EC number (for enzymes)
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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier	GO ID	GO term name	Reference(s)	Evidence Code	with/from	Aspect	Notes	Status
	GO:0005215	transporter activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000515	F	Seeded from EcoCyc ^[5]	complete
	GO:0006865	amino acid transport	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0029	P	Seeded from EcoCyc 12.5 ^[6]	complete
	GO:0016020	membrane	GO_REF:0000002 GO_REF:0000004 GO_REF:0000004	IEA: Inferred from Electronic Annotation	InterPro:IPR000515 SP_KW:KW-0397 SP_KW:KW-0472	C	Seeded from EcoCyc 12.5 ^[6]	complete
	GO:0016021	integral to membrane	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0812	C	Seeded from EcoCyc 12.5 ^[6]	complete
	GO:0005886	plasma membrane	GO_REF:0000004 GO_REF:0000004 GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_KW:KW-0997 SP_KW:KW-1003 SP_SL:SL-0037	C	Seeded from EcoCyc ^[5]	complete
	GO:0006810	transport	GO_REF:0000002 GO_REF:0000004	IEA: Inferred from Electronic Annotation	InterPro:IPR000515 SP_KW:KW-0813	P	Seeded from EcoCyc ^[5]	complete
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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type	Partner	Notes	References	Evidence
Protein	Subunits of L- and D-methionine uptake ABC permease	could be indirect
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment	Description	Evidence	Notes
plasma membrane	C-terminus localized in the cytoplasm with 5 predicted transmembrane domains	Daley et al. (2005) ^[7]
plasma membrane			From EcoCyc^[3]
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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence	at EcoCyc MSEPMMWLLV RGVWETLAMT FVSGFFGFVI GLPVGVLLYV TRPGQIIANA KLYRTVSAIV NIFRSIPFII LLVWMIPFTR VIVGTSIGLQ AAIVPLTVGA APFIARMVEN ALLEIPTGLI EASRAMGATP MQIVRKVLLP EALPGLVNAA TITLITLVGY SAMGGAVGAG GLGQIGYQYG YIGYNATVMN TVLVLLVILV YLIQFAGDRI VRAVTRK
Mol. Wt	23.26 kDa (calc) ^[2]
pI
Extinction coefficient	28420 (calc based on 8 Y, 3 W, and 0 C residues)
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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type	Residues	Description	Notes
Domain	13 - 204	ABC transmembrane type-1	UniProt:P31547
Domain	181 - 203	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[8]
Domain	144 - 166	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[8]
Domain	18 - 40	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[8]
Domain	60 - 78	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[8]
Domain	82 - 104	Predicted membrane-spanning helix.	TMD predicted by TMHMM^[8]
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Click the image to view raw output from TMHMM.

Structure See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

Models

View models at:

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type	Source	Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database	Accession	Notes
EcoCyc (EcoliWiki Page)	EcoCyc:METI-MONOMER
UniProt (EcoliWiki Page)	UniProt:P31547
PFAM (EcoliWiki Page)	PFAM:PF00528
RefSeq (EcoliWiki Page)	RefSeq:NP_414740
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Notes

Links

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Name	URL	Comments
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References

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↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 ^2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ ^3.0 ^3.1 ^3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
↑ ^5.0 ^5.1 ^5.2 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
↑ ^6.0 ^6.1 ^6.2 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ Daley, DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308 1321-3 PubMed
↑ ^8.0 ^8.1 ^8.2 ^8.3 ^8.4 Krogh, A et al. (2001) Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. J. Mol. Biol. 305 567-80 PubMed

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 Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
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-complete
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-GO:0006810
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-transport
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-GO_REF:0000002<br />GO_REF:0000004
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-IEA: Inferred from Electronic Annotation
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-InterPro:IPR000515<br />SP_KW:KW-0813
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-P
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-Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
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 complete
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 C
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+Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
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+complete
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+GO:0006810
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+transport
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+GO_REF:0000002<br />GO_REF:0000004
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+IEA: Inferred from Electronic Annotation
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+InterPro:IPR000515<br />SP_KW:KW-0813
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+P
 |
 Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>

metI:Gene Product(s): Difference between revisions

Revision as of 04:40, 12 March 2009

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

Links

References

Categories

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metI:Gene Product(s): Difference between revisions

Revision as of 04:40, 12 March 2009

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

Links

References

Categories

Navigation menu

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